磺胺类药物代谢与残留消除以及检测方法研究进展
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摘要
对磺胺类药物在动物和人体内的代谢与残留消除规律以及残留检测方法进行综述,并展望磺胺类药物的代谢研究方向以及残留检测技术的发展,以期为开发新的磺胺类药物残留检测方法提供技术支持和参考。
This paper summarized metabolism and residue elimination and residue detection methods of sulfonamides. Finally,the research direction of sulfonamides metabolism and residues detection technology was discussed. It is expected to provide technical support and reference for the development of new detection methods for sulfonamides residues.
This paper summarized metabolism and residue elimination and residue detection methods of sulfonamides. Finally,the research direction of sulfonamides metabolism and residues detection technology was discussed. It is expected to provide technical support and reference for the development of new detection methods for sulfonamides residues.
引文
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[12]Mengelers M J B,Gogh E R V,Kuiper H A,et al.Pharmacokinetics of sulfadimethoxine and sulfamethoxazole in combination with trimethoprim after intravenous administration to healthy and pneumonic pigs[J].Journal of Veterinary Pharmacology&Therapeutics,2010,18(4):243-253.
[13]刘兆颖,孙志良.兽药比较代谢研究进展[J].西北农林科技大学学报(自然科学版),2011,39(10):35-40.Liu Z Y,Sun Z L.Rsaearch progress of comparative metabolism of veterinary drugs[J].Journal of Northwest A&F University(Nat.Sci.Ed.),2011,39(10):35-40.
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[15]Ginneken V J T V,Nouws J F M,Grondel J L,et al.Pharmacokinetics of sulphadimidine in carp(Cyprinus carpio L.)and rainbow trout(Salmo gairdneri Richardson)acclimated at two different temperature levels[J].Veterinary Quarterly,1991,13(2):88-96.
[16]林伟.不同水温下口灌磺胺甲噁唑在长丝鲈体内的药动学研究[J].科学养鱼,2017,(3):59-60.Lin W.Pharmacokinetics of sulfamethoxazole in the filaments at different water temperatures[J].Scientific Fish Farming,2017,(3):59-60.
[17]Janus K,Deka A,Kostyrska K,et al.Influence of age and time of day on the pharmacokinetics of sulphadimidine in calves[J].Medycyna Weterynaryjna,2004,60(3):292-295.
[18]王伟利,肖贺,姜兰,等.单次和连续药饵投喂方式下复方磺胺嘧啶在吉富罗非鱼体内的代谢消除规律[J].中国渔业质量与标准,2016,6(1):29-35.Wang W L,Xiao H,Jiang L,et al.Pharmacokinetic and residues of compound sulfadiazine in GIFT(Oreochromis niloticus)at single and multiple dosage[J].China Fishery Quality And Standards,2016,6(1):29-35.
[19]艾晓辉,刘长征,周运涛.不同水温和给药方式下磺胺甲噁唑在草鱼体内的药动学研究[J].水生生物学报,2005,29(2):210-214.Ai X H,Liu C Z,Zhou Y T.A study on pharmacokinetic of sulphamethoxazole in grass crap at different temperatures and administration regimes[J].Acta Hydrobiologica Sinica,2005,29(2):210-214.
[20]侯廷龙,张其中,付耀武.磺胺甲噁唑(SMZ)和甲氧苄啶(TMP)在彭泽鲫组织中的残留消除研究[J].生态科学,2017,36(4):52-57.Hou T L,Zhang Q Z,Fu Y W.Studies on residue elimination of sulfamethoxazole(SMZ)and trimethoprim(TMP)in Carassius auratus var.pengze[J].Ecological Science,2017,36(4):52-57.
[21]陈进军,王元,赵姝,等.复方磺胺嘧啶口灌给药在拟穴青蟹(Scylla paramamosain)体内药动学和组织分布与消除[J].渔业科学进展,2017,38(4):104-110.Chen J J,Wang Y,Zhao S,et al.Pharmacokinetics,Tissue Distribution and Elimination of Sulfadiazine and Trimethoprim in Mud Crab(Scylla paramamosain)After Oral Administration[J].Progress In Fishery Sciences,2017,38(4):104-110.
[22]鞠晶,王伟利,姜兰,等.磺胺间甲氧嘧啶在罗非鱼体内的药物代谢动力学及休药期[J].华中农业大学学报,2015,34(1):103-107.Ju J,Wang W L,Jiang L,et al.Pharmacokinetics and withdrawal period of sulfamonomethoxine in tilapia[J].Journal of Huazhong Agricultural University,2015,34(1):103-107.
[23]孙晨明,徐亚亚,颜卫,等.复方磺胺氯吡嗪钠在鸡体内残留消除研究[J].中国家禽,2016,38(20):56-59.Sun C M,Xu Y Y,Yan W,et al.Study on the elimination of compound sulfachloropyrazine sodium in chicken[J].China Poultry,2016,38(20):56-59.
[24]徐维,曾振灵,权丹,等.磺胺对甲氧嘧啶和二甲氧苄啶在肉鸡体内的残留消除[J].动物医学进展,2016,37(8):49-56.Xu W,Zeng Z L,Quan D,et al.Study on Residue Depletions of Sulfametoxydiazine and Diaveridine in Chickens[J].Progress in Veterinary Medicine,2016,37(8):49-56.
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