部分中药材(饮片)中的亚硫酸盐残留检测
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摘要
针对中药饮片中亚硫酸盐残留给人体造成的危害,加强对其中的亚硫酸盐的残留检测,是当前研究的重点。在比较传统检测方法的基础上,以牛膝等多种药材作为样品,美国戴安公司的离子色谱仪作为试验仪器,采用水蒸气蒸馏检测的方式,将样品进行检测,并与传统的酸碱滴定法进行对比。结果表明,该测定方法在对牡丹皮、白果、山药三种中药中的硫酸根离子测定中,平均回收率可分别达到89.7%、95.2%、93.4%,精密度分别为4.6%、4.1%、8.4%,高于传统滴定法得到的平均回收率和精密度,说明具有一定的可行性。
Considering the harm of sulfite residues in Chinese herbal tablets to human body, to strengthen the detection of sulfite residues is the focus of current research in Chinese herbal tablets. On the basis of comparing the traditional detection methods, the achyranthes bidentata and other medicinal materials are used as samples, and the Diane's ion chromatograph is applied as the test instrument, and the samples are detected by steam distillation, then compared with the one which is detected by traditional acid-base titration method. The results show that the average recovery of sul-fate ion in peony bark, white fruit and yam can reach 89.7%, 95.2% and 93.4% respectively, and the precision is 4.6%, 4.1% and 8.4% respectively,which is higher than the average recovery and precision obtained by traditional titration method. And it is concluded that this method is feasible.
Considering the harm of sulfite residues in Chinese herbal tablets to human body, to strengthen the detection of sulfite residues is the focus of current research in Chinese herbal tablets. On the basis of comparing the traditional detection methods, the achyranthes bidentata and other medicinal materials are used as samples, and the Diane's ion chromatograph is applied as the test instrument, and the samples are detected by steam distillation, then compared with the one which is detected by traditional acid-base titration method. The results show that the average recovery of sul-fate ion in peony bark, white fruit and yam can reach 89.7%, 95.2% and 93.4% respectively, and the precision is 4.6%, 4.1% and 8.4% respectively,which is higher than the average recovery and precision obtained by traditional titration method. And it is concluded that this method is feasible.
引文
[1]纪琳,李东翔,彭缨,等.中药材及饮片中二氧化硫残留的研究进展[J].中国现代中药,2015,17(2):185~190.
[2]陈汀,王玳珠,李梅珍.中药及汤剂中亚硫酸盐残留的研究现状[J].天津中医药大学学报,2018,37(4):271~273.
[3]李晓楠,周勇亮,陈宏,等.表面增强拉曼散射光谱法快速鉴别经硫磺熏蒸的中药饮片[J].分析试验室,2016,35(1):102~106.
[4]许玮仪,王琼,于江泳,等. 10种中药材及饮片亚硫酸盐残留检测结果分析[J].中国药事,2014,28(7):735~740.
[5]吴潍.中药材硫磺熏蒸危害及防止方法[J].中国乡村医药,2013,20(13):43.
[6]彭月,李雪莲,银玲,等.中药材硫熏法加工的研究现状及其二氧化硫残留检测方法[J].中药与临床,2012,3(5):5~8.
[7]许玮仪,李耀磊,高芳,等.中药材及饮片中三种亚硫酸盐残留量测定法的比较研究[J].中国药师,2015,18(5):782~783,786.
[2]陈汀,王玳珠,李梅珍.中药及汤剂中亚硫酸盐残留的研究现状[J].天津中医药大学学报,2018,37(4):271~273.
[3]李晓楠,周勇亮,陈宏,等.表面增强拉曼散射光谱法快速鉴别经硫磺熏蒸的中药饮片[J].分析试验室,2016,35(1):102~106.
[4]许玮仪,王琼,于江泳,等. 10种中药材及饮片亚硫酸盐残留检测结果分析[J].中国药事,2014,28(7):735~740.
[5]吴潍.中药材硫磺熏蒸危害及防止方法[J].中国乡村医药,2013,20(13):43.
[6]彭月,李雪莲,银玲,等.中药材硫熏法加工的研究现状及其二氧化硫残留检测方法[J].中药与临床,2012,3(5):5~8.
[7]许玮仪,李耀磊,高芳,等.中药材及饮片中三种亚硫酸盐残留量测定法的比较研究[J].中国药师,2015,18(5):782~783,786.