增强营养支持对老年慢性阻塞性肺疾病患者肺通气功能和运动耐量的影响
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摘要
目的:观察和探讨增强营养支持对老年慢性阻塞性肺疾病(COPD)患者肺通气功能和运动耐量产生的影响。方法:选取我院2016年1月—2017年12月收治的老年COPD患者120例,根据营养方案分为观察组64例和对照组56例,对照组给予常规营养支持,观察组给予加强营养支持,观察两组营养支持前后的营养水平、肺通气功能变化以及运动耐量等指标,并对两组指标进行比较。结果:营养支持前,两组的体重、血清总蛋白(TP)、白蛋白(ALB)、6min步行距离(6WMD)、最大摄氧量(VO_2max)以及用力肺活量(FVC)、第1秒用力呼气容积(FEV1)和FEV1占预计值百分比(FEV1%)等指标无显著差异(P>0.05),营养支持3w后观察组上述指标明显优于对照组(P<0.05或P<0.01)。结论:增强营养支持能明显改善老年COPD患者的肺通气功能和提高运动耐量,值得在临床推广。
Objective To observe and explore the effect of enhanced nutrition support on pulmonary ventilation function and exercise tolerance in elderly patients with chronic obstructive pulmonary disease(COPD).Method We selected 120 cases of senile COPD patients from January 2016 to December 2017,according to the nutrient solution,the patients were divided into observation group and control group,64 cases in the control group and 56 cases in the control group.The control group was given conventional nutritional support,the observation group was given to strengthen nutrition support.The nutrition level,changes in pulmonary ventilation function and exercise tolerance index of two groups before and after nutritional support were observed and compared.Result Before obtaining nutrition support,there was no significant difference in body weight,serum total protein(TP),albumin(ALB),6min walking distance(6WMD),VO_2Max(VO_2max)and forced vital capacity(FVC),forced expiratory volume in first second(FEV1)and FEV1 percentage of expected value(FEV1%),and other indicators between the two groups(P>0.05).The above indicators were significantly better than the control group after three weeks of nutrition support(P<0.05 or P<0.01).Conclusion Enhanced nutritional support can significantly improve the pulmonary ventilation function and increase the exercise tolerance in elderly patients with COPD,and it is worth promoting in clinical practice.
Objective To observe and explore the effect of enhanced nutrition support on pulmonary ventilation function and exercise tolerance in elderly patients with chronic obstructive pulmonary disease(COPD).Method We selected 120 cases of senile COPD patients from January 2016 to December 2017,according to the nutrient solution,the patients were divided into observation group and control group,64 cases in the control group and 56 cases in the control group.The control group was given conventional nutritional support,the observation group was given to strengthen nutrition support.The nutrition level,changes in pulmonary ventilation function and exercise tolerance index of two groups before and after nutritional support were observed and compared.Result Before obtaining nutrition support,there was no significant difference in body weight,serum total protein(TP),albumin(ALB),6min walking distance(6WMD),VO_2Max(VO_2max)and forced vital capacity(FVC),forced expiratory volume in first second(FEV1)and FEV1 percentage of expected value(FEV1%),and other indicators between the two groups(P>0.05).The above indicators were significantly better than the control group after three weeks of nutrition support(P<0.05 or P<0.01).Conclusion Enhanced nutritional support can significantly improve the pulmonary ventilation function and increase the exercise tolerance in elderly patients with COPD,and it is worth promoting in clinical practice.
引文
[1]高艳芳,区燕云,陈妙媛.五禽戏锻炼的出院过渡期慢性阻塞性肺疾病患者肺功能剂运动耐量的影响[J].临床与病理杂志,2017,37(5):975-980.
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[8]李丽娜,李敬会,蔡莉莉,等.增强营养对老年慢性阻塞性肺疾病患者肺通气功能及运动耐量的影响[J].实用临床医药杂志,2018,22(3):28-31.
[9]甘信荣,田黎,张志坚.肺结核合并慢性阻塞性肺病患者营养状况与肺功能的相关性分析[J].海南医学,2014,25(9):1265-1267.
[10]石劢,陈杰,陈禹,等.慢性阻塞性肺疾病患者的营养评估及营养支持现况调查[J].中国食物与营养,2017,23(12):67-70.
[2]仰柯,魏彩虹,张文广,等.家庭无创通气对COPD并呼吸衰竭患者营养状况及免疫功能的影响[J].中国临床研究,2014,27(6):664-666.
[3]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2013年修订版)[J].中华结核和呼吸杂志,2013,36(4):255-264.
[4]吉瑜虹,赵俊平,张晓珂,等.慢阻肺急性加重期病人肠内营养支持的临床观察[J].肠外与肠内营养,2017(4):237-239.
[5]李雷,史佳.临床肠内营养支持对老年慢性阻塞性肺病患者心肺功能影响的干预研究[J].中华老年心脑血管病杂志,2014,16(6):599-601.
[6]Kitaguchi Y,Fujimoto K,Komatsu Y,et al.Additive efficacy of hort-acting bronchodilators on dynamic hyperinflation and exercise tolerance in stable COPD patients treated with long-actingbronchodilators[J].Respir Med,2013,107(3):394-400.
[7]仝海英.高原地区老年慢性阻塞性肺疾病患者营养状况与肺功能的相关性[J].中国老年学杂志,2016,36(12):2970-2972.
[8]李丽娜,李敬会,蔡莉莉,等.增强营养对老年慢性阻塞性肺疾病患者肺通气功能及运动耐量的影响[J].实用临床医药杂志,2018,22(3):28-31.
[9]甘信荣,田黎,张志坚.肺结核合并慢性阻塞性肺病患者营养状况与肺功能的相关性分析[J].海南医学,2014,25(9):1265-1267.
[10]石劢,陈杰,陈禹,等.慢性阻塞性肺疾病患者的营养评估及营养支持现况调查[J].中国食物与营养,2017,23(12):67-70.