畜禽产品中抗生素残留主要检测技术及应对策略
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摘要
畜禽养殖中抗生素的不合理使用导致我国畜禽产品中抗生素残留问题时有发生。饲用添加或疾病防治是我国抗生素的主要消耗途径。从技术、管理双层面解决抗生素残留问题具有重要意义。在检测技术层面,当前常用的生物检测法和理化检测法具有检测时间长、前处理复杂、成本高等缺点,急需新型检测技术。作者对新型太赫兹检测技术及其应用潜力进行了探讨,又对解决抗生素残留的全流程监控体系的构建提出了思路。
The unreasonable use of antibiotics in livestock farming has led to the problems of antibiotic residues in animal products in China, Feeding or treatment of livestock diseases is the main consumption route of antibiotics in China. The biological detection method and physical and chemical detection method commonly used for antibiotic residues in animal products have the characteristics of long detection time, complicated front, high cost and etc. Terahertz spectroscopy has fast and non-destructive advantages and has a good application prospect in antibiotic residue detection. Solving the problem of antibiotic residues not only requires efforts in testing methods and monitoring systems, but also needs to strengthen and improve the use of antibiotics and improve the management of animals.
The unreasonable use of antibiotics in livestock farming has led to the problems of antibiotic residues in animal products in China, Feeding or treatment of livestock diseases is the main consumption route of antibiotics in China. The biological detection method and physical and chemical detection method commonly used for antibiotic residues in animal products have the characteristics of long detection time, complicated front, high cost and etc. Terahertz spectroscopy has fast and non-destructive advantages and has a good application prospect in antibiotic residue detection. Solving the problem of antibiotic residues not only requires efforts in testing methods and monitoring systems, but also needs to strengthen and improve the use of antibiotics and improve the management of animals.
引文
[1]中国统计局.中国统计年鉴2017,12-14农业-畜产品产量[EB/OL].http://data.stats.gov.cn/tjsj/ndsj2017/indexch.htm.
[2]郭洋.德国食品领域发生“抗生猪”事件[N].中国食品安全报,2012-02-10.
[3]两会提案:抗生素污染严重亟需出台法律法规[EBOL].http://www.chem17.com/news/detail/89503.html,2016-03-07.
[4]王丹,隋倩,赵文涛,等.中国地表水环境中药物和个人护理品的研究进展[J].科学通报,2014,59(09):743-751.
[5]白晓娟.乳品中残留抗生素及其他兽药的种类及检测监控探讨[J].现代食品,2017(17):11-13.
[6]石建军.肉制品中抗生素残留的危害和控制[J].肉类研究,2009(08):69-71.
[7]李丹妮,贡松松,顾欣,等.生鲜牛乳中抗生素残留检测技术研究进展[J].中国乳品工业,2017,45(05)38-42+58.
[8]沈虎琴.畜禽粪便中喹诺酮类与四环素类抗生素残留检测技术的研究[D].合肥:安徽农业大学,2012.
[9]李晓琍.动物性食品中抗生素类药物的残留污染[J].实用预防医学,2004(06):1304-1306.
[10]农业部畜牧兽医局.农业部发布动物性食品中兽药最高残留限量[J].中国兽药杂志,2003(02):7-9.
[11]周伟娥,张元,李伟青,等.动物源性食品中大环内酯类药物前处理及检测方法研究进展[J].食品与发酵工业,2015,41(12):241-247.
[12]Singh B,Kaur J,Singh K.Biotin-avidin mediated competitive enzyme-linked immunosorbent assay to detect residues of tetracyclines in milk[J].Microchemical Journal,2008,88(1):26-31.
[13]孙晓峥,任柯潼,胡叶军,等.肉鸡组织中氟喹诺酮类抗生素快速检测的胶体金技术研究[J].黑龙江畜牧兽医,2018(19):208-213.
[14]王艳,李艳萍,剡根娇.抗生素类药物残留检测前处理及分析方法研究进展[J].山东工业技术,2016(20):292-293.
[15]Casado-Terrones S,Busi S,Dinelli G,et al.Determination of tetracycline residues in honey by CZE with ultraviolet absorbance detection[J].Electrophoresis,2007,28(16):2882-2887.
[16]Yu H,Tao Y,Chen D,et al.Development of an HPLC-UV method for the simultaneous determination of tetracyclines in muscle and liver of porcine,chicken and bovine with accelerated solvent extraction[J].Food Chemistry,2011,124(3):1131-1138.
[17]卢坤,童群义.动物源性食品中抗生素残留检测技术研究进展[J].广州化工,2015(12):13-14.
[18]Hassouan M K,Ballesteros O,Zafra A,et al.Multiresidue method for simultaneous determinationof quinolone antibacterials in pig kidney samples by liquidchromatography with fluorescencedetection[J].JChromatogr B,2007,859(2):282-288.
[19]张敏,张俊,付海滨,等.超高效液相色谱-串联质谱法测定沼肥中六种喹诺酮类抗生素[J].沈阳农业大学学报,2018,49(04):486-490.
[20]秦坚源.四环素类抗生素的太赫兹光谱检测技术研究[D].杭州:浙江大学,2016.
[21]戴浩,徐开俊,金飚兵,等.β-内酰胺类抗生素药物的太赫兹光谱[J].红外与激光工程,2013,42(1):90-95.
[22]朱思原,张曼,沈京玲.磺苄西林、舒他西林、美洛西林、替卡西林的太赫兹指纹谱[J].红外与激光工程,2013,42(3):626-630.
[23]张曼,朱思原,李庆梅,等.太赫兹技术对头孢菌素类抗生素的研究[J].光谱学与光谱分析,2013,33(2):330-333.
[24]吉特,赵红卫,张增艳,等.D-、L-和DL-青霉胺的太赫兹时域光谱[J].物理化学学报,2006,22(9):1159-1162.
[25]顾冬花.动物性食品中抗生素的残留、危害及防控措施[J].山东畜牧兽医,2015(9):78-79.
[26]张远,陈庆富,王永强.动物性食品中抗生素的残留及对策[J].食品与药品,2005,7(12):29-32.
[27]丁朝宽.浅谈养殖业滥用抗生素带来的危害及应对措施[J].中国畜牧兽医文摘,2013(2):22-22.
[28]杜鹃,谢峻,郑颖城,等.《抗生素耐药:全球监测报告2014》解读与反思[J].华南国防医学杂志,2014(8):814-817.
[29]李轶欣.抗生素何去何从[J].猪业科学,2012(3):32-33.
[30]黄玉华,实力可.抗生素使用安全现状与抗生素残留检测技术研究进展[J].食品安全导刊,2014(11):34-35.
[31]陈婷.集约化畜禽养殖中抗生素的合理应用[J].甘肃畜牧兽医,2016,46(07):114-115.
[2]郭洋.德国食品领域发生“抗生猪”事件[N].中国食品安全报,2012-02-10.
[3]两会提案:抗生素污染严重亟需出台法律法规[EBOL].http://www.chem17.com/news/detail/89503.html,2016-03-07.
[4]王丹,隋倩,赵文涛,等.中国地表水环境中药物和个人护理品的研究进展[J].科学通报,2014,59(09):743-751.
[5]白晓娟.乳品中残留抗生素及其他兽药的种类及检测监控探讨[J].现代食品,2017(17):11-13.
[6]石建军.肉制品中抗生素残留的危害和控制[J].肉类研究,2009(08):69-71.
[7]李丹妮,贡松松,顾欣,等.生鲜牛乳中抗生素残留检测技术研究进展[J].中国乳品工业,2017,45(05)38-42+58.
[8]沈虎琴.畜禽粪便中喹诺酮类与四环素类抗生素残留检测技术的研究[D].合肥:安徽农业大学,2012.
[9]李晓琍.动物性食品中抗生素类药物的残留污染[J].实用预防医学,2004(06):1304-1306.
[10]农业部畜牧兽医局.农业部发布动物性食品中兽药最高残留限量[J].中国兽药杂志,2003(02):7-9.
[11]周伟娥,张元,李伟青,等.动物源性食品中大环内酯类药物前处理及检测方法研究进展[J].食品与发酵工业,2015,41(12):241-247.
[12]Singh B,Kaur J,Singh K.Biotin-avidin mediated competitive enzyme-linked immunosorbent assay to detect residues of tetracyclines in milk[J].Microchemical Journal,2008,88(1):26-31.
[13]孙晓峥,任柯潼,胡叶军,等.肉鸡组织中氟喹诺酮类抗生素快速检测的胶体金技术研究[J].黑龙江畜牧兽医,2018(19):208-213.
[14]王艳,李艳萍,剡根娇.抗生素类药物残留检测前处理及分析方法研究进展[J].山东工业技术,2016(20):292-293.
[15]Casado-Terrones S,Busi S,Dinelli G,et al.Determination of tetracycline residues in honey by CZE with ultraviolet absorbance detection[J].Electrophoresis,2007,28(16):2882-2887.
[16]Yu H,Tao Y,Chen D,et al.Development of an HPLC-UV method for the simultaneous determination of tetracyclines in muscle and liver of porcine,chicken and bovine with accelerated solvent extraction[J].Food Chemistry,2011,124(3):1131-1138.
[17]卢坤,童群义.动物源性食品中抗生素残留检测技术研究进展[J].广州化工,2015(12):13-14.
[18]Hassouan M K,Ballesteros O,Zafra A,et al.Multiresidue method for simultaneous determinationof quinolone antibacterials in pig kidney samples by liquidchromatography with fluorescencedetection[J].JChromatogr B,2007,859(2):282-288.
[19]张敏,张俊,付海滨,等.超高效液相色谱-串联质谱法测定沼肥中六种喹诺酮类抗生素[J].沈阳农业大学学报,2018,49(04):486-490.
[20]秦坚源.四环素类抗生素的太赫兹光谱检测技术研究[D].杭州:浙江大学,2016.
[21]戴浩,徐开俊,金飚兵,等.β-内酰胺类抗生素药物的太赫兹光谱[J].红外与激光工程,2013,42(1):90-95.
[22]朱思原,张曼,沈京玲.磺苄西林、舒他西林、美洛西林、替卡西林的太赫兹指纹谱[J].红外与激光工程,2013,42(3):626-630.
[23]张曼,朱思原,李庆梅,等.太赫兹技术对头孢菌素类抗生素的研究[J].光谱学与光谱分析,2013,33(2):330-333.
[24]吉特,赵红卫,张增艳,等.D-、L-和DL-青霉胺的太赫兹时域光谱[J].物理化学学报,2006,22(9):1159-1162.
[25]顾冬花.动物性食品中抗生素的残留、危害及防控措施[J].山东畜牧兽医,2015(9):78-79.
[26]张远,陈庆富,王永强.动物性食品中抗生素的残留及对策[J].食品与药品,2005,7(12):29-32.
[27]丁朝宽.浅谈养殖业滥用抗生素带来的危害及应对措施[J].中国畜牧兽医文摘,2013(2):22-22.
[28]杜鹃,谢峻,郑颖城,等.《抗生素耐药:全球监测报告2014》解读与反思[J].华南国防医学杂志,2014(8):814-817.
[29]李轶欣.抗生素何去何从[J].猪业科学,2012(3):32-33.
[30]黄玉华,实力可.抗生素使用安全现状与抗生素残留检测技术研究进展[J].食品安全导刊,2014(11):34-35.
[31]陈婷.集约化畜禽养殖中抗生素的合理应用[J].甘肃畜牧兽医,2016,46(07):114-115.