武汉市杨园社区居民糖调节受损人群危险因素分析
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摘要
目的了解社区人群糖调节受损(impaired glueose regulation,IGR)的临床特征,探讨其主要危险因素,为制定预防和干预措施提供依据。方法选取武汉市杨园社区卫生服务中心2015年健康档案中IGR人群260例和正常人群100例,比较分析各组间临床特征,运用单因素和多因素非条件Logistic回归分析,探讨影响IGR发生的危险因素。结果单因素分析结果显示,糖调节受损人群中在糖尿病家族史、高血脂、高血压、腰臀比超标、体质指数超标等因素方面差异有统计学意义(P<0.05);多因素非条件Logistic回归分析结果提示,糖尿病家族史(χ~2=6.16,P=0.01)、高血脂因素(χ~2=5.57,P=0.02)差异有统计学意义(P<0.05)。结论有糖尿病家族史、高血脂、高血压、腰臀比超标、体质指数超标等为糖调节受损人群相关风险因子,有糖尿病家族史、高血脂为糖调节受损人群的独立危险因素。
Objectives To understand the clinical features of the community population with impaired glucose regulation(IGR),and explore the major risk factors to provide the basis for the development of prevention and intervention measures.Methods 260 cases of IGR residents and 100 cases of heath residents were chosen from the 2015 health record in a community health service center.A comparative analysis of clinical characteristics between groups was made,in which univariate and multivariate unconditional Logistic regression analysis were applied to explore risk factors that affected IGR occurrence.Results Univariate analysis showed that among IGR population:the differences in family history of diabetes,high cholesterol,high blood pressure,excess in waist-hip ratio,excess in body mass index and other factors were statistically significant(P<0.05).Multivariate unconditional logistic regression analysis showed that the differences in family history of diabetes(χ~2=6.16,P=0.01)factor and high blood lipids factor(χ~2=5.57,P=0.02)were statistically significant(P<0.05).Conclusions Family history of diabetes,high cholesterol,and high blood pressure,excess in waist-hip ratio and excess in body mass index are the associated risk factors for people with IGR.Family histories of diabetes and high cholesterol are independent risk factors for people with IGR.
Objectives To understand the clinical features of the community population with impaired glucose regulation(IGR),and explore the major risk factors to provide the basis for the development of prevention and intervention measures.Methods 260 cases of IGR residents and 100 cases of heath residents were chosen from the 2015 health record in a community health service center.A comparative analysis of clinical characteristics between groups was made,in which univariate and multivariate unconditional Logistic regression analysis were applied to explore risk factors that affected IGR occurrence.Results Univariate analysis showed that among IGR population:the differences in family history of diabetes,high cholesterol,high blood pressure,excess in waist-hip ratio,excess in body mass index and other factors were statistically significant(P<0.05).Multivariate unconditional logistic regression analysis showed that the differences in family history of diabetes(χ~2=6.16,P=0.01)factor and high blood lipids factor(χ~2=5.57,P=0.02)were statistically significant(P<0.05).Conclusions Family history of diabetes,high cholesterol,and high blood pressure,excess in waist-hip ratio and excess in body mass index are the associated risk factors for people with IGR.Family histories of diabetes and high cholesterol are independent risk factors for people with IGR.
引文
[1]肖美芳,朱海萍.葡萄糖调节受损的研究进展[J].护理研究,2013,27(3):587-589.
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[8]张淑贞,陈锐亮,陈素婵,等.某市东部沿海地区糖调节受损人群生化指标变化及危险因素分析[J].国际检验医学杂志,2012,33(13):1548-1550.
[9]Li CL,Tsai ST,Chou P.Comparison of metabolic risk profiles between subjects with fasting and 2-hours plasma glucose impairment:the kinmen study[J].J Clin Epidemiol,2002,55(1):19-24.
[10]潘长玉,金文胜.葡萄糖调节受损[J].中华内分泌代谢杂志,2005,21(5):5-8.
[11]王琳,朱德增,张杰等.上海某社区糖调节受损人群的临床特征及其与代谢综合征的关系[J].中国卫生统计,2012,29(2):101-104.
[12]Carnevale Schianca GP,Rossi A,Sainaghi PP,et al.The significance of impaired fasting glucose versus impaired glucose tolerance:importance of insulin secretion and resistance[J].Diabetes Care,2003,26(5):1333-1337.
[13]王申奇,陈惠芬,侯旭宏.糖调节受损患者的临床特征及2年自然转归分析[J].上海交通大学学报(医学版),2011,31(11):1603-1607.
[2]The Diabetes Prevention Program Research Group.The diabetes prevention program:Baseline characteristics of the randomized Cohort[J].Diabetes Care,2000,23(11):1619-1629.
[3]杨宇峰,秦延斌,石岩.益糖康干预糖调节受损的代谢综合征疗效评价[J].中国实验方剂学杂志,2014,22(20):197-199.
[4]阳琰,邓华聪,龙健,等.重庆市居民静坐看电视时间与糖调节受损2型糖尿病的关系[J].重庆医学,2013,42(34):4168-4172.
[5]俞丹,王宏星,华文进,等.代谢综合征高危人群胰岛功能的特点研究[J].中国全科医学,2014,17(5):504-508.
[6]赵世华,王颜刚,王萍,等.山东沿海居民糖尿病及糖尿病前期患病率5年变迁研究[J].中华内分泌代谢杂志,2013,29(1):9-13.
[7]高仲雷,李少丹,沈秋燕,等.温州地区某农村糖代谢异常及危险因素调查分析[J].中国乡村医药杂志,2013,20(5):63-65.
[8]张淑贞,陈锐亮,陈素婵,等.某市东部沿海地区糖调节受损人群生化指标变化及危险因素分析[J].国际检验医学杂志,2012,33(13):1548-1550.
[9]Li CL,Tsai ST,Chou P.Comparison of metabolic risk profiles between subjects with fasting and 2-hours plasma glucose impairment:the kinmen study[J].J Clin Epidemiol,2002,55(1):19-24.
[10]潘长玉,金文胜.葡萄糖调节受损[J].中华内分泌代谢杂志,2005,21(5):5-8.
[11]王琳,朱德增,张杰等.上海某社区糖调节受损人群的临床特征及其与代谢综合征的关系[J].中国卫生统计,2012,29(2):101-104.
[12]Carnevale Schianca GP,Rossi A,Sainaghi PP,et al.The significance of impaired fasting glucose versus impaired glucose tolerance:importance of insulin secretion and resistance[J].Diabetes Care,2003,26(5):1333-1337.
[13]王申奇,陈惠芬,侯旭宏.糖调节受损患者的临床特征及2年自然转归分析[J].上海交通大学学报(医学版),2011,31(11):1603-1607.