土大黄提取物及其有效成分药理活性研究进展
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摘要
土大黄药用历史悠久,为维吾尔医常用药材。近年来,国内外学者对土大黄的化学组成、药理活性进行了较为广泛的研究。化学成分分析表明,土大黄以蒽醌类、黄酮类、萘及萘醌类、二苯乙烯类等成分为主;药理实验及临床报道表明,土大黄在抗炎、抗病毒、抗肿瘤、抗氧化和抗免疫等方面具有重要作用。通过查阅国内外相关文献,总结了土大黄提取物及其有效成分的药理活性及作用机制,为该药临床研究提供理论参考,以期为其开发利用提供依据。
Rumex madaio is a common medicine in Uighur medicine with a long history. In recent years,scholars at home and abroad have studied the chemical constituents and pharmacological activities of Rumex madaio.Component analysis showed that there were anthraquinones, flavonoids, naphthalene and naphthoquinones,stilbenes and other components in Rumex madaio. Clinical reports and pharmacological tests showed that Rumex madaio has an important role in anti-inflammatory, antiviral, antitumor, antioxidant and immune suppression.Therefore,it is of clinical significance to review the activities of various active constituents of Rumex madaio. In this paper, the pharmacological activities and mechanisms of different active components of Rumex madaio were summarized through literature review, which provided a theoretical basis for the clinical study of this herbal medicine,and the future basis for its development and utilization.
Rumex madaio is a common medicine in Uighur medicine with a long history. In recent years,scholars at home and abroad have studied the chemical constituents and pharmacological activities of Rumex madaio.Component analysis showed that there were anthraquinones, flavonoids, naphthalene and naphthoquinones,stilbenes and other components in Rumex madaio. Clinical reports and pharmacological tests showed that Rumex madaio has an important role in anti-inflammatory, antiviral, antitumor, antioxidant and immune suppression.Therefore,it is of clinical significance to review the activities of various active constituents of Rumex madaio. In this paper, the pharmacological activities and mechanisms of different active components of Rumex madaio were summarized through literature review, which provided a theoretical basis for the clinical study of this herbal medicine,and the future basis for its development and utilization.
引文
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