热毒宁注射液治疗成人支气管肺炎40例
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摘要
目的:观察热毒宁注射液治疗成人支气管肺炎的临床疗效。方法:将80例患者随机分为观察组和对照组,每组40例。对照组行西药治疗,观察组在对照组治疗的基础上采用热毒宁注射液治疗,2组均连续治疗3天后,比较2组肺功能、临床症状缓解时间及氧化应激因子水平。结果:第一秒用力呼气容积(FEV_1%)、潮气量,并计算第一秒用力肺活量/潮气量比值(FEV_1/FVC)治疗后2组比较差异有统计学意义(P<0.05)。咳嗽咳痰、肺部干湿啰音及气促等临床症状消失时间2组比较,差异有统计学意义(P<0.05)。丙二醛(MDA)、超氧化物歧化酶(SOD)、谷光甘肽过氧化物酶(GSH-px)水平2组比较,差异有统计学意义(P<0.05)。结论:热毒宁注射液治疗成人支气管肺炎,能有效改善患者肺功能,减轻患者临床症状,提高机体抗氧化能力。
Objective:To observe clinical effects of ReDuNing injection in treating adult alveobronchiolitis.Methods: Eighty patients were randomly allocated to the observation group and the control group, 40 cases each group, the control group accepted Western medicine, and the observation group ReDuNing injection based on the therapy of Western medicine, the levels of oxidative stress factor, remission time of clinical symptoms and pulmonary function of both groups were compared after they were treated for three days consecutively. Results: The difference had statistical meaning in the comparisons of FEV_1%, tidal volume and the ratio of forced vital capacity of the first second to tidal volume after treating between both groups(P <0.05). The difference was statistically significant in the comparisons of the disappearing time of clinical symptoms including cough, expectoration, lung dry and wet rale, panting and others between both groups(P<0.05). The difference showed statistical meaning in the comparisons of the levels of MDA, SOD and GSH-px between both groups(P<0.05). Conclusion: ReDuNing injection applied to adult alveobronchiolitis could effectively improve lung function of the patients, rapidly relieve clinical symptoms of the patients and raise antioxidant capacity of adults.
Objective:To observe clinical effects of ReDuNing injection in treating adult alveobronchiolitis.Methods: Eighty patients were randomly allocated to the observation group and the control group, 40 cases each group, the control group accepted Western medicine, and the observation group ReDuNing injection based on the therapy of Western medicine, the levels of oxidative stress factor, remission time of clinical symptoms and pulmonary function of both groups were compared after they were treated for three days consecutively. Results: The difference had statistical meaning in the comparisons of FEV_1%, tidal volume and the ratio of forced vital capacity of the first second to tidal volume after treating between both groups(P <0.05). The difference was statistically significant in the comparisons of the disappearing time of clinical symptoms including cough, expectoration, lung dry and wet rale, panting and others between both groups(P<0.05). The difference showed statistical meaning in the comparisons of the levels of MDA, SOD and GSH-px between both groups(P<0.05). Conclusion: ReDuNing injection applied to adult alveobronchiolitis could effectively improve lung function of the patients, rapidly relieve clinical symptoms of the patients and raise antioxidant capacity of adults.
引文
[1]陈阳,丁银云,曹美华,等.热毒宁注射液辅助治疗儿童支气管肺炎100例疗效分析[J].吉林医学,2014,35(26):5805-5808.
[2]李娜.热毒宁注射液辅助治疗小儿支气管肺炎的疗效分析[J].基层医学论坛,2016,20(27):3782-3783.
[3]祁丽娟,张宏,张旭亚.热毒宁注射液辅助治疗儿童支气管肺炎疗效研究[J].中国实用医药,2014,6(21):172-173.
[4]刘志侠.热毒宁结合头孢噻啶治疗小儿支气管肺炎的疗效观察[J].中国继续医学数育,2015,7(31):215-217.
[5]林金弟,陈德伟.热毒宁注射液联合拉氧头孢钠治疗小儿支气管肺炎的效果评价[J].中国当代医药,2016,23(28):105-107.
[6]陈绪文,刘易芳.热毒宁注射液辅助治疗婴儿急性支气管肺炎71例疗效分析[J].河北联合大学学报:医学版,2015,15(3):379-380.
[7]赵娟,朱媛媛.热毒宁注射液治疗儿童支气管肺炎的疗效观察[J].中国中西医结合儿科学,2015,7(6):625-627.
[8]李郁,周永红,傅存冀,等.热毒宁注射液治疗儿童支气管肺炎的临床观察[J].中国医院用药评价与分析,2014,13(8):725-728.
[9]胡月凤.热毒宁注射液联合头孢地嗪钠治疗儿童支气管肺炎的临床效果分析[J].中国当代医药,2014,21(25):115-117.
[10]陈德祥.热毒宁注射液治疗35例小儿支气管肺炎的临床效果[J].世界最新医学信息文摘,2016,16(17):149-151.
[11]陈现慧.热毒宁注射液治疗小儿支气管肺炎的临床分析[J].临床医药文献杂志,2017,4(1):146-148.
[12]刘须峰.热毒宁注射液治疗小儿支气管肺炎的疗效观察[J].临床合理用药,2014,7(11):52-53.
[13]郭亚波.热毒宁注射液治疗小儿支气管肺炎80例[J].中国中医药现代远程教育,2016,14(5):49-50.
[14]董艳萍.热毒宁注射液治疗小儿支气管肺炎65例[J].河南中医,2014,34(9):1846-1847.
[15]张春霞.热毒宁注射液治疗小儿支气管肺炎疗效观察[J].贵阳中医学院学报,2014,35(6):174-175.
[16]刘磊,刘洁,曾晓红.痰热清及热毒宁治疗小儿支气管肺炎的疗效比较[J].新疆中医药,2014,32(3):14-15.
[17]刘宏丽.热毒宁注射液治疗小儿支气管肺炎的有效性与安全性[J].中国医药指南,2015,17(11):209-210.
[18]杜莹,关惠予.炎琥宁与热毒宁治疗儿童支气管肺炎的疗效及药物经济学比较[J].临床合理用药,2017,10(3):64-65.
[2]李娜.热毒宁注射液辅助治疗小儿支气管肺炎的疗效分析[J].基层医学论坛,2016,20(27):3782-3783.
[3]祁丽娟,张宏,张旭亚.热毒宁注射液辅助治疗儿童支气管肺炎疗效研究[J].中国实用医药,2014,6(21):172-173.
[4]刘志侠.热毒宁结合头孢噻啶治疗小儿支气管肺炎的疗效观察[J].中国继续医学数育,2015,7(31):215-217.
[5]林金弟,陈德伟.热毒宁注射液联合拉氧头孢钠治疗小儿支气管肺炎的效果评价[J].中国当代医药,2016,23(28):105-107.
[6]陈绪文,刘易芳.热毒宁注射液辅助治疗婴儿急性支气管肺炎71例疗效分析[J].河北联合大学学报:医学版,2015,15(3):379-380.
[7]赵娟,朱媛媛.热毒宁注射液治疗儿童支气管肺炎的疗效观察[J].中国中西医结合儿科学,2015,7(6):625-627.
[8]李郁,周永红,傅存冀,等.热毒宁注射液治疗儿童支气管肺炎的临床观察[J].中国医院用药评价与分析,2014,13(8):725-728.
[9]胡月凤.热毒宁注射液联合头孢地嗪钠治疗儿童支气管肺炎的临床效果分析[J].中国当代医药,2014,21(25):115-117.
[10]陈德祥.热毒宁注射液治疗35例小儿支气管肺炎的临床效果[J].世界最新医学信息文摘,2016,16(17):149-151.
[11]陈现慧.热毒宁注射液治疗小儿支气管肺炎的临床分析[J].临床医药文献杂志,2017,4(1):146-148.
[12]刘须峰.热毒宁注射液治疗小儿支气管肺炎的疗效观察[J].临床合理用药,2014,7(11):52-53.
[13]郭亚波.热毒宁注射液治疗小儿支气管肺炎80例[J].中国中医药现代远程教育,2016,14(5):49-50.
[14]董艳萍.热毒宁注射液治疗小儿支气管肺炎65例[J].河南中医,2014,34(9):1846-1847.
[15]张春霞.热毒宁注射液治疗小儿支气管肺炎疗效观察[J].贵阳中医学院学报,2014,35(6):174-175.
[16]刘磊,刘洁,曾晓红.痰热清及热毒宁治疗小儿支气管肺炎的疗效比较[J].新疆中医药,2014,32(3):14-15.
[17]刘宏丽.热毒宁注射液治疗小儿支气管肺炎的有效性与安全性[J].中国医药指南,2015,17(11):209-210.
[18]杜莹,关惠予.炎琥宁与热毒宁治疗儿童支气管肺炎的疗效及药物经济学比较[J].临床合理用药,2017,10(3):64-65.