中医肺胃同治疗法对老年COPD稳定期患者肺功能的影响
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摘要
目的探讨中医肺胃同治疗法对老年COPD稳定期患者肺功能的影响。方法选取本院2014年5月—2016年5月中医内科门诊和住院部收治的确诊为COPD患者80例,采用随机数字表法将其分对照组和治疗组,每组各40例,对照组患者予以常规治疗,治疗组患者予以二陈汤联合厚朴麻黄汤加味治疗,观察2组患者治疗前后后肺功能各项指标改善情况、临床症状和体征积分改善情况及疗效、不良反应、并发症。结果治疗后肺功能、血气指标及咳嗽、咳痰、喘息、胃纳、啰音等临床症状和体征均显著改善,和治疗前比较差异差异均较明显(P<0.05),治疗组改善情况较对照组更为明显,差异有具有统计学意义(P<0.05),且治疗后对照组总有效率为75.00%明显低于治疗组的92.50%,统计学方法检测结果为(χ2=4.5006,P=0.0339),治疗期间2组患者均未发生严重不良反应及并发症。结论中医肺胃同治疗法对老年COPD稳定期患者肺功能及缺氧状态有显著的改善,且疗效显著、安全性高,临床应用前景广阔。
Objective: To investigate the effect of Lung and Stomach Common Therapy on pulmonary function in elderly patients with stable COPD. Methods: 80 COPD patients who were admitted to the department of internal medicine and inpatient department of tradition Chinese medicine from May 2014 to May 2016,were selected and divided into a control group and a treatment group by random number table method,40 cases per group. The control group was treated with conventional method while the treatment group was treated with Erchen Decoction combined with Magnolia officinalis mahuang Decoction. The improvement of lung function index and the improvement of clinical symptoms and signs scores,curative effect,side effects and complications were observed before and after the treatment. Results: After the treatment,the clinical symptoms and signs such as cough,sputum,wheezing,appetite and rale,improved significantly,and the difference was significant( P < 0. 05). The treatment group significantly improved better than the control group( P < 0. 05),and the total effective rate of the control group after the treatment was 75. 00%,significantly lower than 92. 50% of the treatment group. The statistical test results was χ2= 4. 5006,( P < 0. 05),and the difference was statistically significant( P < P = 0. 0339). There were no serious adverse reactions and complications in both groups during the treatment. Conclusion: The lung and stomach common therapy of TCM can improve the pulmonary function and hypoxia of the elderly patients with stable COPD,and the curative effect is obvious and safe and has a wide clinical application prospect.
Objective: To investigate the effect of Lung and Stomach Common Therapy on pulmonary function in elderly patients with stable COPD. Methods: 80 COPD patients who were admitted to the department of internal medicine and inpatient department of tradition Chinese medicine from May 2014 to May 2016,were selected and divided into a control group and a treatment group by random number table method,40 cases per group. The control group was treated with conventional method while the treatment group was treated with Erchen Decoction combined with Magnolia officinalis mahuang Decoction. The improvement of lung function index and the improvement of clinical symptoms and signs scores,curative effect,side effects and complications were observed before and after the treatment. Results: After the treatment,the clinical symptoms and signs such as cough,sputum,wheezing,appetite and rale,improved significantly,and the difference was significant( P < 0. 05). The treatment group significantly improved better than the control group( P < 0. 05),and the total effective rate of the control group after the treatment was 75. 00%,significantly lower than 92. 50% of the treatment group. The statistical test results was χ2= 4. 5006,( P < 0. 05),and the difference was statistically significant( P < P = 0. 0339). There were no serious adverse reactions and complications in both groups during the treatment. Conclusion: The lung and stomach common therapy of TCM can improve the pulmonary function and hypoxia of the elderly patients with stable COPD,and the curative effect is obvious and safe and has a wide clinical application prospect.
引文
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[7]刘晓莹,张伟.从肺胃相关探讨特发性肺纤维化合并胃食管反流的发病机制及其防治[J].湖北中医药大学学报,2016,18(3):65-67.
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[9]文幸,符文彬,王谦,等.COPD稳定期患者中医辨证分型与背俞穴阳性反应点的相关性[J].中国老年学杂志,2013,33(7):1557-1558.
[2]王振伟,杨佩兰,汤杰,等.中医肺康复操对COPD患者肺功能及急性发作的随机对照研究[J].中国中医急症,2013,22(1):23-24,58.
[3]徐卫方,哈木拉提·吾甫尔,李风森,等.基于代谢组学分析COPD肾虚痰瘀证与异常黑胆质证共性特征[J].科技导报,2013,31(24):55-61.
[4]付玲,刘勇.罗玲老师采用肺胃同治法治疗胃食管反流性咳嗽经验[J].内蒙古中医药,2014,33(15):41.
[5]刘炜,葛正行,李波,等.慢性阻塞性肺疾病患者中医体质分布特点及其与证候的关系研究[J].中国中药杂志,2013,38(20):3587-3590.
[6]龙芙蓉,欧璐,苏飞,等.慢性阻塞性肺疾病急性发作期中医护理方案优化与实践研究[J].护士进修杂志,2016,31(13):1160-1162.
[7]刘晓莹,张伟.从肺胃相关探讨特发性肺纤维化合并胃食管反流的发病机制及其防治[J].湖北中医药大学学报,2016,18(3):65-67.
[8]苏庆侦.COPD患者肺功能变化与中医痰、瘀、虚证的关系研究[J].中国继续医学教育,2015,(8):240-241.
[9]文幸,符文彬,王谦,等.COPD稳定期患者中医辨证分型与背俞穴阳性反应点的相关性[J].中国老年学杂志,2013,33(7):1557-1558.