PET/CT检查采用不同静脉注射法注射18F-FDG显像剂的准确性和辐射防护影响
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摘要
目的探讨PET/CT检查采用不同静脉注射法注射18F-FDG显像剂的准确性和辐射防护影响。方法选取2017年6—7月在我院接受检查的的70例PET/CT受检者为研究对象,随机将其等分为观察组和对照组,观察组患者采用改良直接注射法,对照组患者采用三通管注射法,显影剂均采用18F-FDG(7. 2±0. 2) m Ci,比较两组患者注射器内残留药物放射性活度,同时,采用活度计测量记录其放射性显影剂时间。结果观察组患者注射器内残余药物放射性明显低于对照组,差异有统计学意义(P <0. 05);但两组患者放射性显像时间比较,差异无统计学意义(P> 0. 05)。结论对于PET/CT检查者采用改良直接法,可有效降低注射器内18F-FDG显像剂的残余量和放射性活度,与三通管注射法相比注射剂量精准,但临床操作中遭受残余药物辐射时间不会增加,值得临床推广应用。
Objective To investigate the effect to accuracy and radiation protection of different intravenous injections of 18 F-FDG imaging agents in PET/CT examination. Methods To compare the residual drug radioactivity in the syringes,and measure and record the time of radioactive developer using a viability meter,70 cases of PET/CT examinees who were examined in our hospital from June to July 2017 were observed,and were randomly divided into study group and control group with equal members. The study group adopted the modified direct injection,while the control group adopted the T-injection.The developer was all 18 F-FDG( 7. 2 ± 0. 2) m Ci. Results The residual drug radioactivity in the syringe of the study group was significantly lower than that of the control group,and the difference was statistically significant( P < 0. 05). There was no statistical significance in the difference of radiographic imaging time between the two groups( P > 0. 05). Conclusion For the PET/CT examiner,the improved direct method could effectively reduce the residual amount and radioactive activity of the 18 F-FDG imaging agent in the syringe. Compared with the T-injection,the injection dose is more accurate,but the radiation exposure time to residual drug during clinical operation will not increase. It was worthy of clinical promotion and application.
Objective To investigate the effect to accuracy and radiation protection of different intravenous injections of 18 F-FDG imaging agents in PET/CT examination. Methods To compare the residual drug radioactivity in the syringes,and measure and record the time of radioactive developer using a viability meter,70 cases of PET/CT examinees who were examined in our hospital from June to July 2017 were observed,and were randomly divided into study group and control group with equal members. The study group adopted the modified direct injection,while the control group adopted the T-injection.The developer was all 18 F-FDG( 7. 2 ± 0. 2) m Ci. Results The residual drug radioactivity in the syringe of the study group was significantly lower than that of the control group,and the difference was statistically significant( P < 0. 05). There was no statistical significance in the difference of radiographic imaging time between the two groups( P > 0. 05). Conclusion For the PET/CT examiner,the improved direct method could effectively reduce the residual amount and radioactive activity of the 18 F-FDG imaging agent in the syringe. Compared with the T-injection,the injection dose is more accurate,but the radiation exposure time to residual drug during clinical operation will not increase. It was worthy of clinical promotion and application.
引文
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[9]王珍,吴湖炳,王全师,等.18F-FDG PET/CT在胆囊癌鉴别诊断及分期中的应用价值[J].中华核医学与分子影像杂志,2016,36(5):402-407.
[10]杨超,丘建燊,张芨,等.18F-FDG PET/CT在肺内多发病灶穿刺部位选择中的临床价值[J].中国临床医学影像杂志,2017,28(1):30-34.
[2]程远,王振光.18F-FDG PET/CT全身显像辐射剂量估计及风险评价[J].中华核医学与分子影像杂志,2017,37(7):430-433.
[3]孔令海,陈玲艳,李雪琴,等.PET/CT检查中18F-FDG所致患者和放射工作人员辐射剂量估算[J].中国职业医学,2017,44(5):646-649.
[4]刘莉,张建,左长京,等.18F-FDG PET/CT双时相显像在胰腺癌与胰腺炎性病变鉴别诊断中的价值[J].中华核医学与分子影像杂志,2017,37(8):449-455.
[5]杨晖,关志伟,富丽萍,等.18F-FDG PET/CT在肝外胆管细胞癌术前诊断及分期中的价值[J].中华核医学与分子影像杂志,2017,37(2):65-69.
[6]李雪娜,李娜,杜补林,等.18F-FDG PET/CT显像对胃肠肿瘤术后肠梗阻病因学的诊断价值[J].中国医科大学学报,2016,45(5):422-425.
[7]付蔷,徐文贵,于筱舟,等.18F-FDG PET/CT在无症状肿瘤标志物升高患者中的应用价值研究[J].中国肿瘤临床,2016,43(23):1026-1030.
[8]Lebriz Uslu,Jessica Donig,Michael Link,等.18F-FDG PET与18F-FDG PET/CT在儿童恶性肿瘤评估中的价值[J].中华核医学与分子影像杂志,2017,37(6):370-381.
[9]王珍,吴湖炳,王全师,等.18F-FDG PET/CT在胆囊癌鉴别诊断及分期中的应用价值[J].中华核医学与分子影像杂志,2016,36(5):402-407.
[10]杨超,丘建燊,张芨,等.18F-FDG PET/CT在肺内多发病灶穿刺部位选择中的临床价值[J].中国临床医学影像杂志,2017,28(1):30-34.