从中西医角度浅述2型糖尿病与恶性肿瘤的关系
摘要
<正>恶性肿瘤与2型糖尿病(type 2 diabetes m ellitus,T2DM)均是威胁人类健康的两大疾病,多年来二者的发病率都呈持续上升趋势。流行病学研究表明,与非糖尿患者群相比,T2DM患者肿瘤发生更为常见。早在20世纪初,就有学者[1]提出T2DM与肿瘤的发生存在统计学上的相关性。20世纪30年代,Wilson等[2]提出T2DM与肿瘤发生有关。至1960年,人群研究提示,T2DM和肿瘤之间可能存在一定的相关
引文
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[2]Wilson EB,Maher HC.Cancer and tuberculosis with some conmments on cancer and other diseases[J].Am J Cancer,1932,16(2):227-250.
[3]Herdan G.The frequency of cancer in diabetes mellitus.Br JCancer,1960,14(4):49-56.
[4]Jee SH,Ohrr H,Sull JW,et al.Fasting serum glucose level and cancer risk in Korean men and women[J].JAMA,2005,293(2):194-202.
[5]Rapp K,Schroeder J,Klenk J,et al.Fasting blood glucose and cancer risk in a cohort of more than 140 000 adults in Austria[J].Diabetologia,2006,49(5):945-952.
[6]Davila JA,Morgan RO,Shaib Y,et al.Diabetes increa-ses therisk of hepatocellular carcinoma in the United States:a population based case control study.Gut,2005,54:533-539.
[7]Ren X,Zhang X,Zhang X,et al Type 2 diabetes mellitus associated with in creased risk for colorectal cancer:evidence from an international ecological study and population-based risk analysis in China[J].Public Health,2009,123(8):540-5441.
[8]Kasper JS,Gionvannucci E.A meta-analysis of diabetes mellitus and the risk of prostate cancer[J].Cancer Epidemiol Biomarkers Prev,2006,15(11):2056-2062.
[9]Edward Giovannucci MD,David M,Harlan MD,et al.Diabetes and Cancer:A Consensus Report[J].A Cancer Journal for Clinicians,2010,60(4):207-221.
[10]王爱萍,刘超,蒋克春,等.关于2型糖尿病患者合并恶性肿瘤临床特点的调查[J].南京医科大学学报,2009,29,(1)102.105.
[11]Vigneri P,Frasca F,SciaccaL,et a.l Diabetes and cancer[J].Endocr Relat Cancer,2009,16(4):1103-1123.
[12]Gupta K,Krishnaswamy G,Karnad A,Peiris AW.Type 2 diabetes mellitus as risk factor for colorectal cancer[J].Am J Med Sci,2002,323(3):140-145.
[13]Parekh N,Okada T,Lu-Yao GL.Obesity,Insulin Resistance,and Cancer Prognosis:Implications for Practice for Providing Careamong Cancer Survivors[J].J Am Diet Assoc,2009,109(8):1346-1353.
[14]Chang CK,Ulrich CM.Hyperinsulinaemia and hyperglycaemia:possible risk factors of colorectal cancer among diabetic patients[J].Diabbetologia,2003,46(5):595-607.
[15]Giovannucci E,Harlon DM,Archer MC,et a1.Diabetes and Cancer:A consensus report.Diabetes Care,2010,33:1674-1685.
[16]Vigneri P,Frasca F,SciaccaL,et a.l Diabetes and cancer[J].Endocr Relat Cancer,2009,16(4):1103-1123.
[17]陈四清.周仲瑛教授从癌毒辨治肿瘤经验[J].新中医,2004,36(2):7-9.
[18]凌昌全.“癌毒”是恶性肿瘤之根本[J].中西医结合学报,2008,6(2):112-113.
[19]张青,王笑民.基于“癌毒”的肿瘤发生发展规律探讨[C].第三届国际中医、中西医结合肿瘤学术交流大会暨第十二届全国中西医结合肿瘤学术大会论文汇编,2010.
[20]袁海燕,李素娟.恶性肿瘤血瘀证研究[J].辽宁中医杂志,2005,32(7):663-664.