右美托咪定对糖尿病患者全麻诱导期间心率变异性的影响研究
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摘要
目的探究在糖尿病人全麻诱导期间应用右美托咪定对心率变异性的影响。方法选取该院2017年1—12月收治的80例糖尿病患者为对象,实验组使用右美托咪定麻醉诱导;对照组用等量生理盐水替代。比对两组麻醉效果。结果实验组在负荷量结束至插管5 min间HR减缓,MAR降低,与静息时相比差异有统计学意义(P<0.05);实验组患在插管后1 min HR减缓,负荷量结束时MAP降低,与对照组相比差异有统计学意义(P<0.05)。结论在糖尿病患者全麻诱导期间应用右美托咪定不会对心率变异性造成显著影响,其影响较小,对于气道插管反应有一定的抑制作用。
Objective This paper tries to investigate the effect of dexmedetomidine on heart rate variability during general anesthesia induction in diabeti c patients. Methods 80 patients with diabetes in this hospital as subjects from January to December 2017 were selected. The experimental group used dexmedetomidine to induce anesthesia; the control group was replaced with the same amount of normal saline. The anesthetic effects of the two groups were compared. Results In the experimental group, the HR slowed down from the end of the loading to 5 minutes after intubation, and the MAR decreased,which was statistically different from that at rest(P<0.05). The experimental group experienced a slower HR at 1 min after intubation, and decreased MAP at the end of the loading. There was a statistically significant difference compared with the control group(P<0.05). Conclusion The application of dexmedetomidine during the induction of general anesthesia in patients with diabetes will not have a significant effect on heart rate variability, its effect is small, and it has a certain inhibitory effect on airway intubation.
Objective This paper tries to investigate the effect of dexmedetomidine on heart rate variability during general anesthesia induction in diabeti c patients. Methods 80 patients with diabetes in this hospital as subjects from January to December 2017 were selected. The experimental group used dexmedetomidine to induce anesthesia; the control group was replaced with the same amount of normal saline. The anesthetic effects of the two groups were compared. Results In the experimental group, the HR slowed down from the end of the loading to 5 minutes after intubation, and the MAR decreased,which was statistically different from that at rest(P<0.05). The experimental group experienced a slower HR at 1 min after intubation, and decreased MAP at the end of the loading. There was a statistically significant difference compared with the control group(P<0.05). Conclusion The application of dexmedetomidine during the induction of general anesthesia in patients with diabetes will not have a significant effect on heart rate variability, its effect is small, and it has a certain inhibitory effect on airway intubation.
引文
[1]王莉,郝雪莲,孙媛,等.右美托咪定对老年糖尿病患者止血带性心肌损伤的影响[J].中国老年学杂志,2017,37(24):6134-6137.
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[5]刘红燕,王巧荣.右美托咪定对老年增生性糖尿病视网膜病变玻璃体切除术糖化血红蛋白水平影响及其与白细胞介素-18、骨桥蛋白的相关性[J].中国老年学杂志,2017,37(19):4851-4852.
[6]谢淑芬,谢海辉,张曙,等.右美托咪定对老年2型糖尿病患者全麻气管插管期心血管反应的影响[J].中国实用医药,2017,12(8):117-119.
[7]童希忠,陈勇,郎海丽,等.右美托咪定对糖尿病大鼠体液免疫及补体的影响[J].中国老年学杂志,2017,37(3):564-565.
[8]张小龙.右美托咪定预给药对行冠脉搭桥术老年2型糖尿病病人围术期神经系统的影响[J].中西医结合心脑血管病杂志,2016,14(22):2680-2683.
[2]汪忠玉,曾资平,张燕,等.右美托咪定对糖尿病大鼠肺组织的保护作用[J].中国实验诊断学,2017,21(12):2177-2180.
[3]胡静,谷小雨,孟炎,等.右美托咪定后处理对糖尿病大鼠心肌缺血再灌注损伤及炎症反应的影响[J].南方医科大学学报,2017,37(11):1506-1511.
[4]张美兰.右美托咪定对2型糖尿病患者上腹部手术心率变异性的影响研究[J].吉林医学,2017,38(11):2102-2103.
[5]刘红燕,王巧荣.右美托咪定对老年增生性糖尿病视网膜病变玻璃体切除术糖化血红蛋白水平影响及其与白细胞介素-18、骨桥蛋白的相关性[J].中国老年学杂志,2017,37(19):4851-4852.
[6]谢淑芬,谢海辉,张曙,等.右美托咪定对老年2型糖尿病患者全麻气管插管期心血管反应的影响[J].中国实用医药,2017,12(8):117-119.
[7]童希忠,陈勇,郎海丽,等.右美托咪定对糖尿病大鼠体液免疫及补体的影响[J].中国老年学杂志,2017,37(3):564-565.
[8]张小龙.右美托咪定预给药对行冠脉搭桥术老年2型糖尿病病人围术期神经系统的影响[J].中西医结合心脑血管病杂志,2016,14(22):2680-2683.