等离子体聚合改性对医用钛表面性能的影响
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摘要
采用低温等离子体聚合改性技术在医用钛表面聚合丙烯胺单体,沉积一层聚合物改性层,在此过程中,以氮等离子体注入作为预处理,研究等离子体预处理对表面丙烯胺聚合改性层的性能影响。采用扫描电子显微镜、原子力显微镜、以及能谱分析、傅里叶红外光谱分析仪对不同条件下等离子体聚合物表面改性层的形貌、拓扑结构、官能团结构及化学成分进行研究,以及通过表面接触角测试仪分析表面亲水性能。结果显示,低温表面等离子体聚合手段能够在钛合金表面形成一层厚度可以调节的纳米聚合物改性层,电化学测试表明,聚合物改性层能够提高表面耐腐蚀性能;接触角测试表明表面聚合物改性层能够提高钛合金表面的亲水性能;FTIR分析表明低温表面等离子体聚合手段能够很好的保留丙烯胺中的氨基官能团,因此能够改善聚合物层的生物活性,有利于细胞的生长。同时,氮的注入之所以能够提高丙烯胺表面聚合物层与基体的结合效率,是因为氮等离子体注入预处理能够在钛合金表面形成梯度结构的过度TiN层,能够有利于等离子聚合过程中–C–N、C–H、–C–NH2、–O=C–NH2等官能团与基体之间的键合。
We used the low temperature plasma polymerization technique to obtain one layer of propylene amine on the surface of titanium. During this process, for comparison, nitrogen plasma plasma immersion ion implantation(N-PIII) was carried out before polymerization of allylamine polymer. Scanning electron microscope(SEM), atomic force microscopy(AFM) and Fourier infrared spectrum(FTIR) were used to examine the surface characteristics of plasma polymerized Ti, such as surface morphology, topological structure, functional structure and chemical composition. In addition, the surface hydrophilicity and corrosion resistance were also measured by surface contact angle tester and electrochemical potentiodynamic polarization tests, respectively. Results show that a layer of polymerized allylamine formed on the surface of titanium. The hydrophilicity can also be improved. FTIR analysis shows that this layer can keep good amino functional groups of allyl amine, favoring the bioactivity of the polymer layers and the growth of bone cells. Furthermore, the nitrogen injection can improve the combination of allyl amine polymer layer and substrate efficiency, because the nitrogen plasma injection pretreatment can form excessive gradient structure of TiN layer on titanium alloy surface, and help the process of plasma polymerization-C-N,-C-H,-C-NH2,-O=C-NH2 and other functional groups and the bonding between the matrix.
We used the low temperature plasma polymerization technique to obtain one layer of propylene amine on the surface of titanium. During this process, for comparison, nitrogen plasma plasma immersion ion implantation(N-PIII) was carried out before polymerization of allylamine polymer. Scanning electron microscope(SEM), atomic force microscopy(AFM) and Fourier infrared spectrum(FTIR) were used to examine the surface characteristics of plasma polymerized Ti, such as surface morphology, topological structure, functional structure and chemical composition. In addition, the surface hydrophilicity and corrosion resistance were also measured by surface contact angle tester and electrochemical potentiodynamic polarization tests, respectively. Results show that a layer of polymerized allylamine formed on the surface of titanium. The hydrophilicity can also be improved. FTIR analysis shows that this layer can keep good amino functional groups of allyl amine, favoring the bioactivity of the polymer layers and the growth of bone cells. Furthermore, the nitrogen injection can improve the combination of allyl amine polymer layer and substrate efficiency, because the nitrogen plasma injection pretreatment can form excessive gradient structure of TiN layer on titanium alloy surface, and help the process of plasma polymerization-C-N,-C-H,-C-NH2,-O=C-NH2 and other functional groups and the bonding between the matrix.
引文
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[2]Dumas V,Rattner A,Vico L et al.Journal of Biomedical Materials Research Part A[J],2012,100(11):3108
[3]Roguska A,Pisarek M,Andrzejczuk M et al.Journal of Biomedical Materials Research A[J],2012,100(8):1954
[4]Nie F L,Zheng Y F,Wei S et al.Journal of Biomedical Materials Research A[J],2013,101(6):1694
[5]Biesiekierski A,Wang J,Gepreel M A H et al.Acta Biomater[J],2012,8(5):1661
[6]McMahon R E,Ma J,Verkhoturov S V et al.Acta Biomater[J],2012,8(7):2863
[7]Meng G L,Liu J,Pei G X et al.Rare Metal Materials and Engineering[J],2011,40(2):533
[8]Liu X M,Wu S L,Yeung K W K et al.Biomaterials[J],2011,32(2):330
[9]Turkez H,Yousef M I,Geyikoglu F.Food and Chemical Toxicology[J],2010,48:2741
[10]Cavusoglu K,Yalcin E.Journal of Environmental Biology[J],2010,31:661
[11]Wu S L,Liu X M,Chan Y L et al.Journal of Biomedical Materials Research Part A[J],2007,81:948
[12]Liu X Y,Chu P K,Ding C X.Materials Science and Engineering:Reports[R],2004,47(2-4):49
[13]Feng Bo(冯波),Weng Jie(翁杰),Qu Shunxin(屈树新)et al.Rare Metal Materials and Engineering(稀有金属材料与工程)[J],2007,36(10):1693
[14]Kokubo T,Kim H M,Kawashita M et al.Journal of Materials Science:Materials in Medicine[J],2004,15(2):99
[15]Pang Pengshao(庞鹏沙),Chen Liuzhu(陈柳珠),Li Wei(李卫).Materials Review(材料导报)[J],2006,20(3):68
[16]Stevens M M,George J H.Science[J],2005,310:1135
[17]Liu X M,Wu S L,Chu P K et al.Journal of Nanoscience and Nanotechnology[J],2009,9:3449
[18]Liu X M,Wu S L,Chan Y L et al.Materials Science and Engineering A[J],2007,444:192
[19]Liu X M,Wu S L,Chu P K et al.Applied Surface Science[J],2007,253(6):3154
[20]Liu X M,Wu S L,Chan Y L et al.Journal of Biomedical Materials Research A[J],2007,82(2):469
[21]Tocce E J,Broderick A H,Murphy K C et al.Journal of Biomedical Materials Research Part A[J],2012,100(1):84
[22]Ma C F,Nagai A,Yamazaki Y et al.Acta Biomater[J],2012,8(2):860
[23]Terriza A,Diaz-Cuenca A,Yubero F et al.Journal of Biomedical Materials Research A[J],2013,101(4):1026
[24]Li P H,Wu G S,Xu R Z et al.Materials Letters[J],2012,89:5