本草基因组学在中药材新品种选育中的应用
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  • 英文篇名:Application of Herbgenomics in Breeding of New Varieties of Chinese Herbal Medicines
  • 作者:尉广飞 ; 董林林 ; 陈士林 ; 李孟芝
  • 英文作者:WEI Guang-fei;DONG Lin-lin;CHEN Shi-lin;LI Meng-zhi;Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences;
  • 关键词:本草基因组学 ; 中药材 ; 优质品种 ; 分子辅助选择 ; 选育 ; 分子标记
  • 英文关键词:herbgenomics;;Chinese herbal medicines;;high-quality cultivars;;molecular-assisted selection;;breeding;;molecular markers
  • 中文刊名:ZSFX
  • 英文刊名:Chinese Journal of Experimental Traditional Medical Formulae
  • 机构:中国中医科学院中药研究所;
  • 出版日期:2018-08-23 14:54
  • 出版单位:中国实验方剂学杂志
  • 年:2018
  • 期:v.24
  • 基金:北京市科技新星项目(Z181100006218020);; 云南省科技厅科技人才和平台计划项目(2017IC038);; 国家自然科学基金青年基金项目(81603238)
  • 语种:中文;
  • 页:ZSFX201823002
  • 页数:11
  • CN:23
  • ISSN:11-3495/R
  • 分类号:26-36
摘要
针对中药材传统育种周期长、效率低等问题,本研究团队提出基于本草基因组学辅助中药材优质新品种选育的策略。通过分析中药材的基因组、转录组、简化基因组等,获得大量单核苷酸多态性(SNP),简单重复序列(SSR)等标记,结合中药材高产、优质、抗逆等目标性状,辅助中药材新品种的选育,如紫苏高产新品种"中研肥苏1号"、三七抗病新品种"苗乡抗七1号"等。然而中药材种类繁多,研究基础薄弱,应通过加强中药材组学研究为其新品种优质基因筛选提供标记,同时建立分子育种和传统选育的综合技术,实现分子标记与优良性状的连锁,加快优质中药材的选育进程,以保障中药材的安全有效。
        The issues of traditional breeding of Chinese herbal medicines is long period and low efficiency. Aimed to above problems,our research team puts forward that the herbgenomics assists the breeding of high-quality new cultivars of Chinese medicinal materials. Through the analysis of the genome, transcriptome,simplified genome and others,a large of single nucleotide polymorphism( SNP),simple sequence repeat( SSR)and other makers were obtained,combined with high-yield,high-quality,resistance and other target traits,and then asssisted the breeding of new cultivars,such as high-yield cultivars"Zhongyan Feisu No. 1"and anti-disease cultivars "Miaoxiang Kangqi No. 1 ". However,the cultivars of Chinese herbal medicines are various and the research foundation is weak. It is necessary to provide molecular markers for the screening of high-quality genes by strengthening the study of herbgenomics. At the same time, a comprehensive breeding technique combining molecular breeding with traditional breeding should be established to achieve the linkage of molecular markers and excellent traits,and accelerate the breeding process of high-quality Chinese herbal medicines,so as to ensure the safety and effectiveness of Chinese herbal medicines.
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