健脾通络汤合生肌红玉膏治疗Ⅲ～Ⅳ期褥疮临床观察
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摘要
目的:观察健脾通络汤合生肌红玉膏治疗Ⅲ~Ⅳ期褥疮的临床疗效及安全性。方法:将59例Ⅲ~Ⅳ期褥疮患者随机分为治疗组30例和对照组29例,治疗组予自制生肌红玉膏外敷加自拟健脾通络汤内服,对照组以湿润烧伤膏外用,对比观察两组疗效。结果:治疗组脾虚血瘀证候评分改善、肉芽组织生长状态、创面愈合率、愈合时间等方面均优于对照组(P<0.05);治疗组总有效率优于对照组(P<0.05)。结论:生肌红玉膏合健脾通络汤治疗Ⅲ~Ⅳ褥疮临床疗效确切,能改善患者体质,促进肉芽组织生长及创面愈合。
Objective: To investigate the clinical efficacy and safety of Jianpi Tongluo decoction and Shengji Hongyu ointment in the treatment of Ⅲ-Ⅳ decuditus ulcer. Methods: The 59 cases of patients with Ⅲ-Ⅳstages decuditus ulcer were randomly divided into treatment group(n=30) and control group(n=29). The patients were treated by Jianpi Tongluo decoction and Shengji Hongyu ointment in treatment grouo, and moisture exposed burn ointment(MEBO) in control group. The curative effect wa compared between the two groups. Results: The treatment group showed better improvement of spleen deficiency scores, granulation tissue growth state, cure time and healing rates than the control group(P <0.05). The treatment group showed higher total effective rate than the control group(P<0.05). Conclusion: Jianpi Tongluo decoction and Shengji Hongyu ointment showed accurate efficacy on Ⅲ-Ⅳ decuditus ulcer; this treatment can improve the constitution and promote granulation tissue growth and wound healing.
Objective: To investigate the clinical efficacy and safety of Jianpi Tongluo decoction and Shengji Hongyu ointment in the treatment of Ⅲ-Ⅳ decuditus ulcer. Methods: The 59 cases of patients with Ⅲ-Ⅳstages decuditus ulcer were randomly divided into treatment group(n=30) and control group(n=29). The patients were treated by Jianpi Tongluo decoction and Shengji Hongyu ointment in treatment grouo, and moisture exposed burn ointment(MEBO) in control group. The curative effect wa compared between the two groups. Results: The treatment group showed better improvement of spleen deficiency scores, granulation tissue growth state, cure time and healing rates than the control group(P <0.05). The treatment group showed higher total effective rate than the control group(P<0.05). Conclusion: Jianpi Tongluo decoction and Shengji Hongyu ointment showed accurate efficacy on Ⅲ-Ⅳ decuditus ulcer; this treatment can improve the constitution and promote granulation tissue growth and wound healing.
引文
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[10]邹国友,郑闽前,贾伟涛,等.自体富含血小板血浆凝胶治疗Ⅳ期褥疮探讨[J].中华老年医学杂志,2014,33(12):1338-1340.
[11]黄帝内经·素问[M].北京:华文出版社,2010:123.
[12]彭曙辉.京万红软膏联合牛黄解毒片治愈Ⅳ期褥疮1例[J].中医药导报,2011,17(11):94-95.
[13]王静.“褥疮散”外敷结合光子治疗仪治疗Ⅲ期褥疮32例临床研究[J].江苏中药,2016,48(2):49-50.
[14]李克盛,张志勇.半导体激光联合中药外敷治疗慢性下肢静脉性溃疡40例临床观察[J].中医药导报,2013,19(2):49-50.
[15]李铁安.苯扎氯铵联合生肌膏对疮面细菌清除和愈合作用的临床观察[J].天津医药,2013,41(12):1211-1213.
[16]Krasner DL,Me Neil M.Six strategies for minimizing wound pain:translating the results from a US pain survey into clinical practice[J].Extended Care Product News,2008,125(11):16-21.
[2]Rutges JP,Oner FC.An exploratory study of pressure ulcers after spinal cord injury:relationship to protective behaviors and risk gactors[J].Arch Phys Med Rehabil,2001,82(1):107-113.
[3]National Pressure Ulcer Advisory Panel.2007 National Pressure Ulcer staing Definition[J].Wound Counc Enterostm Therap J,2007(3):30-31.
[4]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:361-391.
[5]王朝亮,黄素芳,朱涛,等.复方黄柏液湿敷加半导体激光照射治疗感染性褥疮的疗效观察[J].中华医学杂志,2014,94(31):2455-2459.
[6]李然伟,徐冰,张其慧,等.浅谈中风并发症的护理与康复[J].中医药导报,2011,17(18):87-88.
[7]周银根.生肌愈疡散对老年褥疮的疗效及护理体会[J].中医药导报,2012,18(9):123-124.
[8]Strecker W.Decubitus Ulcers:Pathophysiology and Primary Prevention[J].Deutsch Arztebl Int,2010,107(39):692.
[9]杨春晖,龚君辉,黄文娟.自制封闭式负压引流装置结合生肌玉红膏治疗难愈性褥疮[J].中国中西医结合外科杂志,2015,21(1):80-81.
[10]邹国友,郑闽前,贾伟涛,等.自体富含血小板血浆凝胶治疗Ⅳ期褥疮探讨[J].中华老年医学杂志,2014,33(12):1338-1340.
[11]黄帝内经·素问[M].北京:华文出版社,2010:123.
[12]彭曙辉.京万红软膏联合牛黄解毒片治愈Ⅳ期褥疮1例[J].中医药导报,2011,17(11):94-95.
[13]王静.“褥疮散”外敷结合光子治疗仪治疗Ⅲ期褥疮32例临床研究[J].江苏中药,2016,48(2):49-50.
[14]李克盛,张志勇.半导体激光联合中药外敷治疗慢性下肢静脉性溃疡40例临床观察[J].中医药导报,2013,19(2):49-50.
[15]李铁安.苯扎氯铵联合生肌膏对疮面细菌清除和愈合作用的临床观察[J].天津医药,2013,41(12):1211-1213.
[16]Krasner DL,Me Neil M.Six strategies for minimizing wound pain:translating the results from a US pain survey into clinical practice[J].Extended Care Product News,2008,125(11):16-21.