布氏杆菌病疫苗研究进展
摘要
布氏杆菌病是由布氏杆菌引起的人兽共患病,患病母畜流产、胎衣滞留、子宫炎、阴道炎和乳腺炎等;患病公畜表现为睾丸发炎、肿大、上缩,精索粗硬,附睾炎、阴囊肿大。而目前防控布氏杆菌病的重要手段就是通过疫苗进行防控,近些年来布氏杆菌病疫苗发展迅速,主要介绍了4类重要的布氏杆菌病疫苗,期望对布氏杆菌病的预防提供帮助。
引文
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[6]KIM W K,MOON J Y,CHO J S,et al.Protective efficacy of an inactivated Brucella abortus vaccine candidate lysed by GI24against brucellosis in Korean black goats[J].Can J Vet Res,2019,83(1):68-74.
[7]CHEN B,LIU B,ZHAO Z,et al.Evaluation of a DNA vaccine encoding Brucella Bvr R in BALB/c mice[J].Mol Med Rep,2019,19(2):1302-1308.
[8]郝新国.布氏杆菌病疫苗的研究进展[J].郑州牧业工程高等专科学校学报,2009,29(4):16-18.
[9]PASQUEVICH K A,ESTEIN S M,SAMARTINO C G,et al.Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+and CD8+T cells as well as systemic and oral protection against Brucella abortus infection[J].Infection and immunity,2009,77(1):436-445.
[10]YANG X,HUDSON M,WALTERS N,et al.Selection of protective epitopes for Brucella melitensis by DNA vaccination[J].Infection and immunity,2005,73(11):7297-7303.
[11]TABATABAI L B,PUGH G W J.Modulation of immune responses in Balb/c mice vaccinated with Brucella abortus CuZn superoxide dismutase synthetic peptide vaccine[J].Vaccine,1994,12(10):919-924.
[2]SCHURIG G G,SRIRANGANATHAN N,CORBEL M J.Brucellosisvaccines:Past,present and future[J].Vet Microbiol,2002,90:479-496.
[3]SCHURIG G G,ND R R,BAGCHI T,et al.Biological properties of RB51;a stable rough strain of Brucella abortus[J].Veterinary microbiology,1991,28(2):171-188.
[4]LALSIAMTHARA J,LEE J H.Development and trial of vaccines against Brucella[J].Journal of veterinary science,2017,18(Suppl 1):281-290.
[5]BLASCO J M,GAMAZO C,WINTER A J,et al.Evaluation of whole cell and subcellular vaccines against Brucella ovis in rams[J].Veterinary immunology&immunopathology,1993,37(3-4):257-270.
[6]KIM W K,MOON J Y,CHO J S,et al.Protective efficacy of an inactivated Brucella abortus vaccine candidate lysed by GI24against brucellosis in Korean black goats[J].Can J Vet Res,2019,83(1):68-74.
[7]CHEN B,LIU B,ZHAO Z,et al.Evaluation of a DNA vaccine encoding Brucella Bvr R in BALB/c mice[J].Mol Med Rep,2019,19(2):1302-1308.
[8]郝新国.布氏杆菌病疫苗的研究进展[J].郑州牧业工程高等专科学校学报,2009,29(4):16-18.
[9]PASQUEVICH K A,ESTEIN S M,SAMARTINO C G,et al.Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+and CD8+T cells as well as systemic and oral protection against Brucella abortus infection[J].Infection and immunity,2009,77(1):436-445.
[10]YANG X,HUDSON M,WALTERS N,et al.Selection of protective epitopes for Brucella melitensis by DNA vaccination[J].Infection and immunity,2005,73(11):7297-7303.
[11]TABATABAI L B,PUGH G W J.Modulation of immune responses in Balb/c mice vaccinated with Brucella abortus CuZn superoxide dismutase synthetic peptide vaccine[J].Vaccine,1994,12(10):919-924.