摘要
目的探讨动脉瘤性蛛网膜下腔出血患者不同时段认知功能的变化。方法对2015年7月至2017年12月符合纳入标准的122例动脉瘤性蛛网膜下腔出血患者在术前、早期(术后2周)、中期(术后2月)、远期(术后1年)采用简易精神状态量表(MMSE)进行认知功能评价;进行统计学分析。结果术前、早期、中期、远期的MMSE评分分别为:23.30±5.06、20.80±5.68、25.53±3.62、27.79±2.05,F=58.19,P<0.05;认知功能障碍发生率分别为63.11%、80.33%、53.28%、22.95%。结论动脉瘤性蛛网膜下腔出血患者认知功能在不同时段变化,术后早期认知功能障碍最严重,在术后2月恢复到术前水平,在术后1年仍部分存在认知功能障碍,术后2周~1年是认知功能快速恢复阶段。
Objective To investigate the changes of cognitive function in patients with aneurysmal subarachnoid hemorrhage. Methods 122 patients with aneurysmal subarachnoid hemorrhage who met the inclusion criteria from July 2015 to December 2017 were enrolled. Mini-mental state scale(MMSE) were evaluated before operation, early(2 weeks after operation), middle period(2 months after operation) and long term(one year after operation). Results The MMSE scores respectively were 23.30 ±5.06, 20.80 ±5.68, 25.53 ±3.62, 27.79 ±2.05, F =58.19, P <0.05, and the incidence of cognitive dysfunction respectively were 63.11%, 80.33%, 53.28, 22.95%. Conclusion The cognitive function of patients with aneurysmal subarachnoid hemorrhage changed in different time periods, the most serious cognitive dysfunction was in the early postoperative period,and recovered to the preoperative level at 2 months after operation. There was still some cognitive dysfunction in patients one year after operation.From 2 weeks to 1 year after operation, the cognitive function recovered rapidly.
引文
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