半夏白术天麻汤治疗前庭性偏头痛临床观察
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摘要
目的观察半夏白术天麻汤治疗前庭性偏头痛的临床效果。方法回顾性分析我院2017年1月—2018年2月收治的130例前庭性偏头痛患者的临床资料。根据用药情况分为观察组70例和对照组60例。对照组给予甲磺酸倍他司汀口服,观察组在对照组基础上给予半夏白术天麻汤治疗。观察2组临床疗效,比较2组治疗前后累计发病次数和天数,眩晕残障评分(DHI)、健康状况评分量表(SF-36)、汉密尔顿焦虑量表(HAMA)及抑郁量表(HRSD)评分变化情况。结果观察组总有效率高于对照组(P<0.05)。治疗后2组DHI、HAMA和HRSD评分均较治疗前降低,累计发病次数与天数较治疗前减少,SF-36评分较治疗前升高,且观察组改善情况优于对照组(P<0.05)。结论中西医联合治疗前庭性偏头痛效果显著,可明显提高患者生活质量。
Objective To observe clinical effect of Banxia Baizhu Tianma Decoction in Treatment of patients with vestibular migraine(VM). Methods Clinical data of 130 patients with VM admitted during January 2017 and February 2018 was retrospectively analyzed, and the patients were divided into observation group(n=70) and control group(n=60) according to different medications. Control group was treated with Betahistine Mesylate orally, while observation group was added with Banxia Baizhu Tianma Decoction on the basis of treatment for control group. In two groups, clinical effects were observed, and changes of cumulative incidence times and days, scores of vertigo handicap inventory(DHI) scale, health status scale(SF-36), Hamilton anxiety(HAMA) scale and Hamilton rating scale for depression(HRSD) were compared before and after treatment. Results The total effective rate in observation group was significantly higher than that in control group(P<0.05). After treatment, DHI, HAMA and HRSD scores were significantly lower, and cumulative incidence times and days were decreased, while SF-36 scores were increased compared with those before treatment in two groups, and the improved conditions in observation group were superior than those in control group(P<0.05). Conclusion Combination of traditional Chinese medicine and western medicine may achieve good effect and significantly improve quality of life of patients with vestibular migraine.
Objective To observe clinical effect of Banxia Baizhu Tianma Decoction in Treatment of patients with vestibular migraine(VM). Methods Clinical data of 130 patients with VM admitted during January 2017 and February 2018 was retrospectively analyzed, and the patients were divided into observation group(n=70) and control group(n=60) according to different medications. Control group was treated with Betahistine Mesylate orally, while observation group was added with Banxia Baizhu Tianma Decoction on the basis of treatment for control group. In two groups, clinical effects were observed, and changes of cumulative incidence times and days, scores of vertigo handicap inventory(DHI) scale, health status scale(SF-36), Hamilton anxiety(HAMA) scale and Hamilton rating scale for depression(HRSD) were compared before and after treatment. Results The total effective rate in observation group was significantly higher than that in control group(P<0.05). After treatment, DHI, HAMA and HRSD scores were significantly lower, and cumulative incidence times and days were decreased, while SF-36 scores were increased compared with those before treatment in two groups, and the improved conditions in observation group were superior than those in control group(P<0.05). Conclusion Combination of traditional Chinese medicine and western medicine may achieve good effect and significantly improve quality of life of patients with vestibular migraine.
引文
[1] 张艺馨,孔庆韬,何增柳,等.神经内科门诊前庭性偏头痛临床特征分析[J].重庆医科大学学报,2015,40(5):708-711.
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[10] 袁庆,刘得龙,余力生,等.氟桂利嗪预防性治疗前庭性偏头痛眩晕发作的前瞻性随机对照研究[J].临床耳鼻咽喉头颈外科杂志,2016,30(10):805-810.
[11] 蒋子栋.关注前庭性偏头痛[J].中华医学杂志,2016,96(5):321-323.
[12] 侯莉,王琦.甲磺酸倍他司汀与尼莫地平治疗神经性耳鸣疗效对比[J].中国药业,2015,24(12):42-43.
[13] 张隆铿.倍他司汀合用尼莫地平治疗偏头痛临床观察[J].河北医学,2006,12(7):680-681.
[14] 张明发,沈雅琴.半夏及其炮制品对神经和循环系统的药理作用研究进展[J].抗感染药学,2017,14(9):1643-1648.
[15] 黄红,刘新民,吕光华.天麻防治神经精神疾病的研究进展[J].中草药,2018,49(9):2188-2194.
[16] 王治中,安永东,杨英,等.半夏白术天麻汤临床应用及实验研究现状[J].西部中医药,2014,27(8):162-164.
[17] Steiner T J,Birbeck G L,Jensen R H,et al.Headache disorders are third cause of disability worldwide[J].J Headache Pain,2015,16:58.
[18] 赵娜,任凤龙.偏头痛并发焦虑抑郁等精神心理症状的相关因素分析[J].中国实用神经疾病杂志,2015,18(1):82-83.
[2] 沙娟娟,靳爱相,姚力.氟桂利嗪联合低频重复经颅磁刺激治疗偏头痛46例[J].陕西医学杂志,2016,45(6):744-745.
[3] 蒋子栋.前庭性偏头痛相关问题再探讨[J].中华耳科学杂志,2016,14(4):486-489.
[4] Formeister E J,Rizk H G,Kohn M A,et al.The Epidemiology of Vestibular Migraine:A Population-based Survey Study[J].Otol Neurotol,2018,39:1037-1044.
[5] 华驾略,李焰生,Lempert T,等.前庭性偏头痛:诊断标准--Barany学会及国际头痛学会共识文件[J].神经病学与神经康复学杂志,2013,10(3):176-178.
[6] 中华中医药学会.中医内科常见病诊疗指南中医病证部分[M].北京:中国中医药出版社,2008:43.
[7] 邹静,冯智英,李颖,等.偏头痛性眩晕临床诊治的前瞻性研究[J].神经病学与神经康复学杂志,2009,6(1):13-16.
[8] Muelleman T,Shew M,Subbarayan R,et al.Epidemiology of dizzy patient population in a neurotology clinic and predictors of peripheral etiology[J].Otol Neurotol,2017,38:870-875.
[9] 姜树军,马维娅.从神经内科角度看头晕及眩晕临床研究的一些新进展[J].中国神经免疫学和神经病学杂志,2015,22(1):1-3,8.
[10] 袁庆,刘得龙,余力生,等.氟桂利嗪预防性治疗前庭性偏头痛眩晕发作的前瞻性随机对照研究[J].临床耳鼻咽喉头颈外科杂志,2016,30(10):805-810.
[11] 蒋子栋.关注前庭性偏头痛[J].中华医学杂志,2016,96(5):321-323.
[12] 侯莉,王琦.甲磺酸倍他司汀与尼莫地平治疗神经性耳鸣疗效对比[J].中国药业,2015,24(12):42-43.
[13] 张隆铿.倍他司汀合用尼莫地平治疗偏头痛临床观察[J].河北医学,2006,12(7):680-681.
[14] 张明发,沈雅琴.半夏及其炮制品对神经和循环系统的药理作用研究进展[J].抗感染药学,2017,14(9):1643-1648.
[15] 黄红,刘新民,吕光华.天麻防治神经精神疾病的研究进展[J].中草药,2018,49(9):2188-2194.
[16] 王治中,安永东,杨英,等.半夏白术天麻汤临床应用及实验研究现状[J].西部中医药,2014,27(8):162-164.
[17] Steiner T J,Birbeck G L,Jensen R H,et al.Headache disorders are third cause of disability worldwide[J].J Headache Pain,2015,16:58.
[18] 赵娜,任凤龙.偏头痛并发焦虑抑郁等精神心理症状的相关因素分析[J].中国实用神经疾病杂志,2015,18(1):82-83.