布地奈德、异丙托溴铵气雾剂联合雾化吸入治疗对肺气肿患者肺功能及血液相关指标的影响
|
摘要
目的探究布地奈德、异丙托溴铵气雾剂联合雾化吸入治疗对肺气肿患者肺功能及血液相关指标的影响。方法以抽签分组法将我院接收的50例肺气肿患者分成A组(n=26)和B组(n=24),其中B组采用异丙托溴铵雾化吸入治疗,而A组采用布地奈德与异丙托溴铵联合雾化吸入治疗。比较两组患者肺功能及血液相关指标的改善效果。结果 A组治疗后肺功能改善情况优于B组,并且A组治疗后PaO2(12.44±0.86)kPa和SaO2(92.15±4.55)kPa均高于B组的PaO2(9.37±0.41)kPa和SaO2(83.66±3.14)k Pa,差异有统计学意义(P<0.05)。结论对肺气肿患者实施治疗期间联合使用布地奈德和异丙托溴铵气雾剂实施雾化治疗,有助于提高患者肺功能水平,有利于改善患者PaO2及SaO2,疗效可靠。
Objective To investigate the effects of budesonide and ipratropium bromide aerosol combined with nebulized inhalation on pulmonary function and blood related indexes in patients with emphysema. Methods 50 patients with emphysema received by our hospital were divided into group A(n=26) and group B(n=24) by batch method. Group B was treated with ipratropium bromide atomized inhalation, while group A was used.Inhalation therapy with budesonide and ipratropium bromide. The improvement of lung function and blood related indicators in the two groups was compared. Results The improvement of lung function in group A was better than that in group B, and PaO2(12.44±0.86) k Pa and SaO2(92.15±4.55)kPa in group A were higher than those in group B(9.37±0.41) kPa and SaO2(83.66±3.14) k Pa, the difference was statistically significant(P<0.05).Conclusion The combination of budesonide and ipratropium bromide aerosol in the treatment of emphysema patients can improve the lung function of patients and improve the patient's PaO2 and SaO2.
Objective To investigate the effects of budesonide and ipratropium bromide aerosol combined with nebulized inhalation on pulmonary function and blood related indexes in patients with emphysema. Methods 50 patients with emphysema received by our hospital were divided into group A(n=26) and group B(n=24) by batch method. Group B was treated with ipratropium bromide atomized inhalation, while group A was used.Inhalation therapy with budesonide and ipratropium bromide. The improvement of lung function and blood related indicators in the two groups was compared. Results The improvement of lung function in group A was better than that in group B, and PaO2(12.44±0.86) k Pa and SaO2(92.15±4.55)kPa in group A were higher than those in group B(9.37±0.41) kPa and SaO2(83.66±3.14) k Pa, the difference was statistically significant(P<0.05).Conclusion The combination of budesonide and ipratropium bromide aerosol in the treatment of emphysema patients can improve the lung function of patients and improve the patient's PaO2 and SaO2.
引文
[1]吴清松,饶平.不同剂量布地奈德联合异丙托溴铵对AECOPD患者主观症状、肺功能及动脉血气指标的影响[J].中国药房,2016,27(20):2816-2819.
[2]杨娟.布地奈德气雾剂与异丙托溴铵气雾剂联合吸入用乙酰半胱氨酸对慢性阻塞性肺疾病患者肺功能及生活质量的影响研究[J].实用心脑肺血管病杂志,2017,4(3):164-166.
[3]茆金星,刘登河.布地奈德与异丙托溴铵联合雾化吸入对慢性阻塞性肺疾病急性加重期肺功能、血气指标及炎症因子的影响[J].中国卫生检验杂志,2017,9(17):2539-2541.
[4]王鹏程,张晓.布地奈德沙丁胺醇联合异丙托溴铵雾化吸入治疗支气管哮喘急性发作临床效果观察[J].河北医学,2015,9(7):1099-1102.
[5]李爱平.布地奈德异丙托溴铵气雾剂联合雾化吸入治疗老年阻塞性肺气肿临床效果观察[J].河北医学,2016,22(5):814-816.
[6]王爽,郑秀艳,孙文华,等.异丙托溴铵与布地奈德对COPD合并Ⅱ型呼吸衰竭患者MDA,SOD,GSH-Px水平及肺功能的影响[J].现代生物医学进展,2015,15(33):6512-6515.
[7]热西汗·依不拉音,夏迪娅·夏木西丁.异丙托溴铵联合布地奈德呼吸机雾化吸入治疗COPD急性加重期患者的疗效观察[J].河北医学,2016,22(11):1774-1776.
[8]侯艳,李继东,薛庆亮,等.布地奈德分别联合异丙托溴铵和沙丁胺醇两种吸入治疗方法对慢性阻塞性肺疾病的疗效及不良反应比较[J].临床军医杂志,2015,43(2):123-125.
[2]杨娟.布地奈德气雾剂与异丙托溴铵气雾剂联合吸入用乙酰半胱氨酸对慢性阻塞性肺疾病患者肺功能及生活质量的影响研究[J].实用心脑肺血管病杂志,2017,4(3):164-166.
[3]茆金星,刘登河.布地奈德与异丙托溴铵联合雾化吸入对慢性阻塞性肺疾病急性加重期肺功能、血气指标及炎症因子的影响[J].中国卫生检验杂志,2017,9(17):2539-2541.
[4]王鹏程,张晓.布地奈德沙丁胺醇联合异丙托溴铵雾化吸入治疗支气管哮喘急性发作临床效果观察[J].河北医学,2015,9(7):1099-1102.
[5]李爱平.布地奈德异丙托溴铵气雾剂联合雾化吸入治疗老年阻塞性肺气肿临床效果观察[J].河北医学,2016,22(5):814-816.
[6]王爽,郑秀艳,孙文华,等.异丙托溴铵与布地奈德对COPD合并Ⅱ型呼吸衰竭患者MDA,SOD,GSH-Px水平及肺功能的影响[J].现代生物医学进展,2015,15(33):6512-6515.
[7]热西汗·依不拉音,夏迪娅·夏木西丁.异丙托溴铵联合布地奈德呼吸机雾化吸入治疗COPD急性加重期患者的疗效观察[J].河北医学,2016,22(11):1774-1776.
[8]侯艳,李继东,薛庆亮,等.布地奈德分别联合异丙托溴铵和沙丁胺醇两种吸入治疗方法对慢性阻塞性肺疾病的疗效及不良反应比较[J].临床军医杂志,2015,43(2):123-125.