早期综合保健干预配合母婴喂养对早产儿智力、运动功能及预后的影响
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摘要
目的:探讨早期综合保健干预配合母婴喂养对早产儿智力、运动功能及预后的影响。方法:选取2015年1月至2016年6月陕西省西安市儿童医院收治的早产儿110例,随机分为研究组和对照组,每组55例。对照组给予常规喂养,研究组给予早期综合保健干预及母婴喂养。比较两组早产儿3个月、6个月及12个月的智力发育指数(MDI)、运动发育指数(PDI),以及1岁内的预后(后遗症)发生率。结果:研究组早产儿6个月、12个月的头围、身长、体重均高于对照组(均P<0.05);研究组早产儿3个月、6个月和12个月的MDI及PDI均高于对照组,差异均具有统计学意义(均P<0.05);研究组后遗症发生率为3.64%,低于对照组的14.55%(P<0.05)。结论:早期综合保健干预配合母婴喂养可促进早产儿的体格、智力和运动发育,减少后遗症的发生,值得推广应用。
Objective:To investigate the effects of early comprehensive health care interventions combined with breastfeeding on intellectual and motor development and prognosis of premature infants.Methods:One hundred and ten preterm infants admitted in our hospital during January 2015 to June 2016 were randomly divided into a study group and a control group,with 55 cases in each group.The infants in the control group were given conventional feeding,while those in the study group were given early comprehensive health care interventions combined with breastfeeding.The mental development index(MDI)and psychomotive development index(PDI)at 3,6 and 12 months as well as the sequelae incidence were compared between the two groups.Results:The head circumference,body length and weight in the study group were higher than those in the control group at 6 and 12 months(P<0.05).The MDI and PDI at 3,6 and 12 months in the study group were higher than those in the control group(P<0.05).The incidence of sequelae in the study group was lower than that in the control group(3.64%vs.14.55%,P<0.05).Conclusion:Early comprehensive health care intervention combined with breastfeeding could improve the physical,intellectual and motor development,and reduce the sequelae incidence of premature infants.
Objective:To investigate the effects of early comprehensive health care interventions combined with breastfeeding on intellectual and motor development and prognosis of premature infants.Methods:One hundred and ten preterm infants admitted in our hospital during January 2015 to June 2016 were randomly divided into a study group and a control group,with 55 cases in each group.The infants in the control group were given conventional feeding,while those in the study group were given early comprehensive health care interventions combined with breastfeeding.The mental development index(MDI)and psychomotive development index(PDI)at 3,6 and 12 months as well as the sequelae incidence were compared between the two groups.Results:The head circumference,body length and weight in the study group were higher than those in the control group at 6 and 12 months(P<0.05).The MDI and PDI at 3,6 and 12 months in the study group were higher than those in the control group(P<0.05).The incidence of sequelae in the study group was lower than that in the control group(3.64%vs.14.55%,P<0.05).Conclusion:Early comprehensive health care intervention combined with breastfeeding could improve the physical,intellectual and motor development,and reduce the sequelae incidence of premature infants.
引文
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[15]万桂莲.早期护理干预措施对早产儿生长发育影响的研究[J].检验医学与临床,2014(8):1111-1113.
[16]MENON R T,SHRESTHA A K,SHIVANNA B.Hyperoxia exposure disrupts adrenomedullin signaling in newborn mice:implications for lung development in premature infants[J].Biochem Biophys Res Commun,2017,487(3):666-671.
[2]李慧丽,卫国,王强,等.早期综合干预对早产儿智能发育的影响[J].中国儿童保健杂志,2014,22(6):654-656.
[3]王小兰,罗华英,黎瑞春,等.多学科早期干预对早产儿体格发育和智力影响的研究[J].中国实用妇科与产科杂志,2016(2):188-191.
[4]RAJPUT N,FILIPOVSKA J,HEWSON M.The effects of routine administration of probiotics on the length of central venous line usage in extremely premature infants[J].Turk J Pediatr,2017,59(1):20-27.
[5]汤淑斌,杜亚梅,胡春维,等.早期综合干预对早产儿早期发育商的影响[J].中国儿童保健杂志,2014,22(12):1331-1333.
[6]HERNANDEZ-DIAZ S,MCELRATH T F,PENNELLP B,et al.Fetal growth and premature delivery in pregnant women on antiepileptic drugs[J].Ann Neurol,2017,82(3):457-465.
[7]PIRIS B S,LOPEZ M M,TORRES VALDIVIESOM J,et al.Improving nutritional practices in premature infants can increase their growth velocity and the breastfeeding rates[J].Acta Paediatr,2017,106(5):768-772.
[8]田园,于广军.早期干预改善早产儿发育结局的研究进展[J].国际儿科学杂志,2014,41(1):94-97.
[9]COSTELLO E K,SUN C L,CARLISLE E M,et al.Candidatus Mycoplasma girerdii replicates,diversifies,and co-occurs with Trichomonas vaginalis in the oral cavity of a premature infant[J].Sci Rep,2017,7(1):3764.
[10]韩炳娟,邹卉,韩炳超,等.早产儿早期干预的研究进展[J].中国妇幼保健,2015,30(7):1146-1148.
[11]ANDESCAVAGE N N,DUPLESSIS A,MCCARTERR,et al.Cerebrospinal fluid and parenchymal brain development and growth in the healthy fetus[J].Dev Neurosci,2016,38(6):420-429.
[12]杨海虹,梁晓红,张露.新生儿窒息早期干预及发育障碍保健康复的临床价值[J].中国药物经济学,2015(7):131-133.
[13]HOGEWIND-SCHOONENBOOM J E,ROVEKAMP-ABELS L W W,DE WIJS-MEIJLER D P M,et al.The effect of maternal milk on tolerance and growth in premature infants:a hypothesis-generating study[J].J Pediatr Gastroenterol Nutr,2017,64(6):971-974.
[14]王爱平,丁春艳,郑莉莉,等.92例早产儿早期干预的效果分析[J].中国妇幼健康研究,2015(3):474-476.
[15]万桂莲.早期护理干预措施对早产儿生长发育影响的研究[J].检验医学与临床,2014(8):1111-1113.
[16]MENON R T,SHRESTHA A K,SHIVANNA B.Hyperoxia exposure disrupts adrenomedullin signaling in newborn mice:implications for lung development in premature infants[J].Biochem Biophys Res Commun,2017,487(3):666-671.