无醇双胍手消毒液在医院CSSD应用效果观察
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摘要
目的观察一种盐酸聚六亚甲基双胍手消毒液用于医院消毒供应中心(CSSD)人员手消毒效果。方法采用悬液定量杀菌试验方法和现场调查法,对该双胍类手消毒液用于医院CSSD人员手消毒效果及满意度进行观察。结果该手消毒液含聚六亚甲基双胍盐酸盐5 300 mg/L,为不含醇的水溶液。用该手消毒液原液作用0. 5 min,对悬液内金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌的杀灭对数值均> 5. 00,对悬液内白色念珠菌的杀灭对数值> 4. 00。用该手消毒液原液擦拭消毒双手,对手上自然菌杀灭对数均值> 1. 00。经调查,医院CSSD使用者均觉得手感满意。结论该双胍类手消毒液对细菌繁殖体和真菌具有快速杀灭效果,对CSSD人员手消毒效果符合卫生手消毒要求,手感满意。
Objective To observe the disinfection effect of polyhexamethylene biguanidine hydrochloride hand antisepsis used in hospital central sterile supply department( CSSD). Methods Using suspension quantitative disinfection test method and on-site investigation method,the disinfection effect and satisfaction of this biguanide hand disinfectant used in staff of hospital CSSD were observed. Results The hand disinfectant contained 5 300 mg/L polyhexamethylene biguanide hydrochloride,which was an alcohol-free aqueous solution. With the stock solution of hand disinfectant for 0. 5 min,the killing logarithmic values of Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli in suspension were all > 5. 00,and the killing logarithmic value of Candida albicans in suspension was > 4. 00. The killing logarithmic mean value of natural bacteria was > 1. 00 by wiping hands with the stock solution of hand disinfectant. The CSSD users of the surveyed hospitals were satisfied. Conclusion The biguanide hand disinfectant has a rapid killing effect on bacterial propagules and fungi. The disinfection effect on CSSD personnel is satisfactory and can meet the requirements of sanitary hand disinfection.
Objective To observe the disinfection effect of polyhexamethylene biguanidine hydrochloride hand antisepsis used in hospital central sterile supply department( CSSD). Methods Using suspension quantitative disinfection test method and on-site investigation method,the disinfection effect and satisfaction of this biguanide hand disinfectant used in staff of hospital CSSD were observed. Results The hand disinfectant contained 5 300 mg/L polyhexamethylene biguanide hydrochloride,which was an alcohol-free aqueous solution. With the stock solution of hand disinfectant for 0. 5 min,the killing logarithmic values of Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli in suspension were all > 5. 00,and the killing logarithmic value of Candida albicans in suspension was > 4. 00. The killing logarithmic mean value of natural bacteria was > 1. 00 by wiping hands with the stock solution of hand disinfectant. The CSSD users of the surveyed hospitals were satisfied. Conclusion The biguanide hand disinfectant has a rapid killing effect on bacterial propagules and fungi. The disinfection effect on CSSD personnel is satisfactory and can meet the requirements of sanitary hand disinfection.
引文
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[9]丁晓静.高效液相色谱在复方化学消毒剂有效成分检测中的应用[J].中国消毒学杂志,2017,34(7):667-674.
[2]邱小华.消毒供应中心护理人员手卫生依从性差的原因分析及干预措施[J].实用临床护理学电子杂志,2017,2(18):172,181.
[3]中华人民共和国卫生部.消毒技术规范[S].2002.
[4]李杨,李付刚.聚六亚甲基双胍盐酸盐的合成及应用[J].精细化工原料及中间体,2011,2:27-29.
[5]张先菊,苏裕心,任哲,等.聚六亚甲基双胍盐酸盐的杀菌活性及现场空气消毒效果观察[J].中国消毒学杂志,2013,30(11):1016-1018.
[6]宋金武,吴清平,邓金花,等.胍类消毒剂的制备、性能与应用[J].广东化工,2009,36(197):58-61.
[7]崔迎春,乔卫红.双胍盐杀菌剂的研究及应用进展[J].中国洗涤用品工业,2009,6:68-71.
[8]王仲,方伟.聚六亚甲基双胍盐酸盐免洗洁手凝胶消毒剂配方设计与质量研究[J].中国消毒学杂志,2017,34(6):507-509.
[9]丁晓静.高效液相色谱在复方化学消毒剂有效成分检测中的应用[J].中国消毒学杂志,2017,34(7):667-674.