针刺治疗病理性网络使用的机制探讨
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摘要
随着社会的发展及电脑、手机的普及,更多的人沉迷于网络之中,而长时间无节制地使用网络会导致心理、生理、社会功能明显受损。目前,对网络成瘾的治疗方法仍存在许多不足,笔者分析后认为,针刺可以作为一种疗效好且安全性高的治疗该病的新手段。同时,还从脏腑功能、神经递质与基因表达等方面来探讨针刺治疗的作用原理和机制。
With the social progress and the popularity of smartphones and laptops, more and more people are obsessed with the use of Internet. However, excessive and uncontrolled use of Internet would bring harms to people's psychological, physiological and social functions. At present, there are still many defects in the treatment of Internet addiction. Based on a scientific analysis, we believe that acupuncture can be used as a new means of treatment with high safety and effectiveness. In addition, we explore the function, principle and working mechanism of acupuncture from the aspects of viscera function, neurotransmitter and gene expression.
With the social progress and the popularity of smartphones and laptops, more and more people are obsessed with the use of Internet. However, excessive and uncontrolled use of Internet would bring harms to people's psychological, physiological and social functions. At present, there are still many defects in the treatment of Internet addiction. Based on a scientific analysis, we believe that acupuncture can be used as a new means of treatment with high safety and effectiveness. In addition, we explore the function, principle and working mechanism of acupuncture from the aspects of viscera function, neurotransmitter and gene expression.
引文
[1]林绚晖.网络成瘾现象研究概述[J].中国临床心理学杂志,2002,10(1):74-76.
[2]Young KS.Internet addiction:the emergence of a new clinical disorder[J].Cyberpsychol Behav,1996,1(3):237-244.
[3]Alavi SS,Alaghemandan H,Maracy MR,et al.Impact of addiction to internet on a number of psychiatric symptoms in students of Isfahan universities,Iran,2010[J].Int J Prev Med,2012,3(2):122-127.
[4]Yeh YC,Ko HC,Wu JY,et al.Gender differences in relationships of actual and virtual social support to Internet addiction mediated through depressive symptoms among college students in Taiwan[J].Cyberpsychol Behav,2008,11(4):485-487.
[5]宋珺,杨凤池.网络成瘾研究进展[J].中国心理卫生杂志,2006,20(11):758-760.
[6]陈西希.电针对IAD患者脑功能影响的f MRI研究[D].成都:成都中医药大学,2012.
[7]张落明.电针对网络瘾患者焦虑状态及静息态脑功能改变的影响[D].成都:成都中医药大学,2012.
[8]张沁园,王晓红,胡春雨.从气血理论探讨网络成瘾的发病机制[J].中医学报,2015,30(12):1764-1766.
[9]杨常青,袁菲,简荣荣.电针联合认知行为疗法治疗互联网成瘾综合征32例[J].中医研究,2014,27(10):56-58.
[10]黄史乐,张春霞,袁梅,等.网络成瘾形成与心的关系及中医辨治探讨[J].新中医,2006(9):8-9.
[11]吴鎏桢,阎俊娟,韩济生.2/100Hz经皮穴位电刺激对27例青少年网络成瘾症的治疗作用[J].中国药物依赖性杂志,2007,16(1):32-35.
[12]唐胜修.针灸治疗网络成瘾障碍的探讨[J].中华实用中西医杂志,2007,20(21):1907.
[13]齐印宝.网络成瘾者前额叶功能异常:事件相关电位MMN和静息态f MRI的研究[D].合肥:安徽医科大学,2011.
[14]Dong G,Devito E,Huang J,et al.Diffusion tensor imaging reveals thalamus and posterior cingulate cortex abnormalities in internet gaming addicts[J].J Psychiatr Res,2012,46(9):1212-1216.
[15]Dong G,Huang J,Du X.Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts[J].Behav Brain Funct,2012,8:41
[16]赵立刚,史榕荇,吴茜,等.电针四神聪穴治疗失眠疗效及脑电地形图观察[J].针灸临床杂志,2011,27(6):35-36.
[17]胡玲香,李雪青,薛斌.药物依赖与脾脏关系的中医理论探讨[J].中国中医基础医学杂志,2004,10(11):10.
[18]王米渠,汪卫东,陈聪,等.鸟瞰七情的病机证治及研究角度[J].现代中西医结合杂志,2006,15(12):1569-1570.
[19]庞隐.中西医结合治疗少年网络成瘾综合征[J].现代中西医结合杂志,2009,18(4):362-363.
[20]Liu MY,Ren YP,Wei WL,et al.Changes of Serotonin(5-HT),5-HT2A receptor,and 5-HT transporter in the SpragueDawley rats of depression,myocardial infarction and myocardial infarction co-exist with depression[J].Chin Med J,2015,128(14):1905.
[21]Lee BW,Stapinski LA.Seeking safety on the internet:relationship between social and problematic internet use[J].J Anxiety Disord,2012,26(1):197-205.
[22]Zhang HX,Jiang WQ,Lin ZG,et al.Comparison of psychological symptoms and serum levels of neurotransmitters in Shanghai adolescents with and without internet addiction disorder:a case-control study[J].PLo S One,2013,8(5):e63089.
[23]Mithell P.Internet addiction:genuine diagnosis or not?[J].Lancet,2000,355(9204):632.
[24]朱天民,金荣疆,陈骥,等.电针对互联网成瘾综合征患者抑郁状态及血清5-HT变化影响的研究[J].中国康复医学杂志,2008,23(10):940-942.
[25]朱天民,金荣疆,钟晓鸣,等.电针结合心理干预对网瘾患者焦虑状态及血清NE变化的影响[J].中国针灸,2008,28(8):561-564.
[26]蔡丽,刘毅.针刺对卒中后抑郁大鼠行为学及单胺类神经递质影响的实验研究[J].江苏中医药,2013,45(10):71-73.
[27]张璐,刘懿萱,段丽萍.肠道菌群与脑—肠轴功能相互影响的研究进展[J].胃肠病学,2014,19(9):563-565.
[28]贾宝辉.电针对慢性应激模型大鼠下丘脑—垂体—肾上腺(HPA)轴调节作用的机理研究[D].北京:北京中医药大学,2005.
[29]Hong SB,Zalesky A,Cocchi,et al.Decreased functional brain connectivity in adolescents with addiction[J].PLo S One,2013,8(2):e57831.
[30]Cash H,Rae CD,Steel AH,et al.Internet addiction:a brief summary of research and practice[J].Curr Psychiatry Rev,2012,8(4):292-298.
[31]陈丽婷,陈燕惠.下丘脑—垂体—肾上腺皮质轴与多巴胺系统的相互调节作用[J].中国儿童保健杂志,2012(12):1098-1100.
[32]Morsinka MC,Van Uemert NU,Steenbergena PJ,et al.Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes[J].Brain Res,2007,11(50):14-20.
[33]马骏,王彦春,甘水咏.电针对帕金森病大鼠行为学及多巴胺能神经元的影响[J].中国针灸,2006,26(9):655-657.
[34]Pitchot W,Herrera C,Ansseau M.HPA axis dysfunction in major depression:relationship to 5-HT(l A)receptor activity[J].Neuropsychobiology,2001,44(2):74-77.
[35]李陕区,杨博,许昌泰.神经递质5-羟色胺研究现状[J].临床医学工程,2010,17(5):145-147.
[36]穆朝娟,王延祜,翟静,等.5-HT与孤独性障碍[J].山东精神医学,2002,15(3):189-191.
[37]Goridis C,Rohrer H.Specfication of catecholaminergic and serotonergic neurons[J].Nat Rev Neurosci,2002,3(7):531-541.
[38]王含彦,唐珍,邓志霖,等.氟西汀对慢性不可预知性轻度应激抑郁模型大鼠下丘脑—垂体—肾上腺轴的影响[J].兰州大学学报:医学版,2016,42(1):16-20.
[39]李喆,孙学礼.下丘脑—垂体—肾上腺轴与抑郁症的相关性[J].中国临床康复,2006(42):130-133
[40]江励华,徐斌,王玲玲.电针与电针合并氟西汀治疗抑郁症的基因谱表达异同的研究[J].时珍国医国药,2010(11):3000-3004.
[41]江励华,王玲玲.电针治疗抑郁症的全基因组表达谱芯片数据分析[J].针刺研究,2010,35(2):83-89.
[42]冯秀梅,陈淑萍,王俊英,等.电针对神经痛和负性情绪大鼠杏仁核内痛感觉和情绪成分相关促皮质激素释放因子受体等基因表达的影响[J].针刺研究,2014,39(6):448-455.
[43]周雨青,刘星,马兰.药物成瘾的神经生物学机制研究[J].生命科学,2014,26(6):593-602.
[44]Mc Quown SC,Wood MA.Epigenetic regulation in substance use disorders[J].Curr Psychiatry Rep,2010,12(2):145-153.
[45]李飞,周美启,胡玲.针灸的基因表达调控效应研究进展[J].安徽中医学院学报,2004(3):62-64.
[2]Young KS.Internet addiction:the emergence of a new clinical disorder[J].Cyberpsychol Behav,1996,1(3):237-244.
[3]Alavi SS,Alaghemandan H,Maracy MR,et al.Impact of addiction to internet on a number of psychiatric symptoms in students of Isfahan universities,Iran,2010[J].Int J Prev Med,2012,3(2):122-127.
[4]Yeh YC,Ko HC,Wu JY,et al.Gender differences in relationships of actual and virtual social support to Internet addiction mediated through depressive symptoms among college students in Taiwan[J].Cyberpsychol Behav,2008,11(4):485-487.
[5]宋珺,杨凤池.网络成瘾研究进展[J].中国心理卫生杂志,2006,20(11):758-760.
[6]陈西希.电针对IAD患者脑功能影响的f MRI研究[D].成都:成都中医药大学,2012.
[7]张落明.电针对网络瘾患者焦虑状态及静息态脑功能改变的影响[D].成都:成都中医药大学,2012.
[8]张沁园,王晓红,胡春雨.从气血理论探讨网络成瘾的发病机制[J].中医学报,2015,30(12):1764-1766.
[9]杨常青,袁菲,简荣荣.电针联合认知行为疗法治疗互联网成瘾综合征32例[J].中医研究,2014,27(10):56-58.
[10]黄史乐,张春霞,袁梅,等.网络成瘾形成与心的关系及中医辨治探讨[J].新中医,2006(9):8-9.
[11]吴鎏桢,阎俊娟,韩济生.2/100Hz经皮穴位电刺激对27例青少年网络成瘾症的治疗作用[J].中国药物依赖性杂志,2007,16(1):32-35.
[12]唐胜修.针灸治疗网络成瘾障碍的探讨[J].中华实用中西医杂志,2007,20(21):1907.
[13]齐印宝.网络成瘾者前额叶功能异常:事件相关电位MMN和静息态f MRI的研究[D].合肥:安徽医科大学,2011.
[14]Dong G,Devito E,Huang J,et al.Diffusion tensor imaging reveals thalamus and posterior cingulate cortex abnormalities in internet gaming addicts[J].J Psychiatr Res,2012,46(9):1212-1216.
[15]Dong G,Huang J,Du X.Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts[J].Behav Brain Funct,2012,8:41
[16]赵立刚,史榕荇,吴茜,等.电针四神聪穴治疗失眠疗效及脑电地形图观察[J].针灸临床杂志,2011,27(6):35-36.
[17]胡玲香,李雪青,薛斌.药物依赖与脾脏关系的中医理论探讨[J].中国中医基础医学杂志,2004,10(11):10.
[18]王米渠,汪卫东,陈聪,等.鸟瞰七情的病机证治及研究角度[J].现代中西医结合杂志,2006,15(12):1569-1570.
[19]庞隐.中西医结合治疗少年网络成瘾综合征[J].现代中西医结合杂志,2009,18(4):362-363.
[20]Liu MY,Ren YP,Wei WL,et al.Changes of Serotonin(5-HT),5-HT2A receptor,and 5-HT transporter in the SpragueDawley rats of depression,myocardial infarction and myocardial infarction co-exist with depression[J].Chin Med J,2015,128(14):1905.
[21]Lee BW,Stapinski LA.Seeking safety on the internet:relationship between social and problematic internet use[J].J Anxiety Disord,2012,26(1):197-205.
[22]Zhang HX,Jiang WQ,Lin ZG,et al.Comparison of psychological symptoms and serum levels of neurotransmitters in Shanghai adolescents with and without internet addiction disorder:a case-control study[J].PLo S One,2013,8(5):e63089.
[23]Mithell P.Internet addiction:genuine diagnosis or not?[J].Lancet,2000,355(9204):632.
[24]朱天民,金荣疆,陈骥,等.电针对互联网成瘾综合征患者抑郁状态及血清5-HT变化影响的研究[J].中国康复医学杂志,2008,23(10):940-942.
[25]朱天民,金荣疆,钟晓鸣,等.电针结合心理干预对网瘾患者焦虑状态及血清NE变化的影响[J].中国针灸,2008,28(8):561-564.
[26]蔡丽,刘毅.针刺对卒中后抑郁大鼠行为学及单胺类神经递质影响的实验研究[J].江苏中医药,2013,45(10):71-73.
[27]张璐,刘懿萱,段丽萍.肠道菌群与脑—肠轴功能相互影响的研究进展[J].胃肠病学,2014,19(9):563-565.
[28]贾宝辉.电针对慢性应激模型大鼠下丘脑—垂体—肾上腺(HPA)轴调节作用的机理研究[D].北京:北京中医药大学,2005.
[29]Hong SB,Zalesky A,Cocchi,et al.Decreased functional brain connectivity in adolescents with addiction[J].PLo S One,2013,8(2):e57831.
[30]Cash H,Rae CD,Steel AH,et al.Internet addiction:a brief summary of research and practice[J].Curr Psychiatry Rev,2012,8(4):292-298.
[31]陈丽婷,陈燕惠.下丘脑—垂体—肾上腺皮质轴与多巴胺系统的相互调节作用[J].中国儿童保健杂志,2012(12):1098-1100.
[32]Morsinka MC,Van Uemert NU,Steenbergena PJ,et al.Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes[J].Brain Res,2007,11(50):14-20.
[33]马骏,王彦春,甘水咏.电针对帕金森病大鼠行为学及多巴胺能神经元的影响[J].中国针灸,2006,26(9):655-657.
[34]Pitchot W,Herrera C,Ansseau M.HPA axis dysfunction in major depression:relationship to 5-HT(l A)receptor activity[J].Neuropsychobiology,2001,44(2):74-77.
[35]李陕区,杨博,许昌泰.神经递质5-羟色胺研究现状[J].临床医学工程,2010,17(5):145-147.
[36]穆朝娟,王延祜,翟静,等.5-HT与孤独性障碍[J].山东精神医学,2002,15(3):189-191.
[37]Goridis C,Rohrer H.Specfication of catecholaminergic and serotonergic neurons[J].Nat Rev Neurosci,2002,3(7):531-541.
[38]王含彦,唐珍,邓志霖,等.氟西汀对慢性不可预知性轻度应激抑郁模型大鼠下丘脑—垂体—肾上腺轴的影响[J].兰州大学学报:医学版,2016,42(1):16-20.
[39]李喆,孙学礼.下丘脑—垂体—肾上腺轴与抑郁症的相关性[J].中国临床康复,2006(42):130-133
[40]江励华,徐斌,王玲玲.电针与电针合并氟西汀治疗抑郁症的基因谱表达异同的研究[J].时珍国医国药,2010(11):3000-3004.
[41]江励华,王玲玲.电针治疗抑郁症的全基因组表达谱芯片数据分析[J].针刺研究,2010,35(2):83-89.
[42]冯秀梅,陈淑萍,王俊英,等.电针对神经痛和负性情绪大鼠杏仁核内痛感觉和情绪成分相关促皮质激素释放因子受体等基因表达的影响[J].针刺研究,2014,39(6):448-455.
[43]周雨青,刘星,马兰.药物成瘾的神经生物学机制研究[J].生命科学,2014,26(6):593-602.
[44]Mc Quown SC,Wood MA.Epigenetic regulation in substance use disorders[J].Curr Psychiatry Rep,2010,12(2):145-153.
[45]李飞,周美启,胡玲.针灸的基因表达调控效应研究进展[J].安徽中医学院学报,2004(3):62-64.