盆腔炎汤保留灌肠联合小剂量氟罗沙星治疗慢性盆腔炎临床疗效研究
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摘要
目的:观察盆腔炎汤保留灌肠联合小剂量氟罗沙星治疗慢性盆腔炎的临床疗效。方法:将80例患者随机分为观察组和对照组,每组40例,对照组服用氟罗沙星,0.4 g/次,1次/d,晨起顿服;观察组使用盆腔炎汤保留灌肠联合减半剂量氟罗沙星治疗,比较2组临床症状缓解时间、不良反应发生率及诺丁汉健康调查问卷评分。结果:腰骶疼痛、白带量多且气臭色黄、神疲乏力等临床症状的缓解时间观察组均早于对照组,2组比较差异有统计学意义(P<0.05)。不良反应发生率观察组为7.5%,对照组为30.0%,2组比较差异有统计学意义(P<0.05)。患者精力、疼痛程度、情感变化、睡眠质量、社会生活适应能力及躯体活动能力诺丁汉健康调查问卷评分,2组比较差异均有统计学意义(P<0.05)。结论:盆腔炎汤保留灌肠联合小剂量氟罗沙星能有效改善患者临床症状,减少不良反应,提高其生活质量。
Objective: To observe clinical effects of PenQiangYan decoction retention enema and small dosage of fleroxacin in treating chronic pelvic inflammation(CPI). Methods: Eighty patients were randomized into the observation group and the control group, 40 cases each group. The control group took fleroxacin, once each day,0.4 g each time, once each day, in the morning; the observation group were treated by PenQiangYan decoction retention enema and half of the dosage of fleroxacin, Nottingham health questionnaire score, the incidence of adverse reaction and the mitigation time of clinical symptoms were compared between both groups. Results: The observation group was earlier than the control group in the mitigation time of clinical symptoms including lumbosacral pain, leukorrhagia, smell and yellow, physical fatigue and feeble, the difference had statistical meaning(P<0.05). The incidence of adverse reaction in the observation group was 7.5%, lower than 30.0% of the control group, and the difference showed statistical meaning(P <0.05). The difference had statistical meaning in the comparisons of Nottingham health questionnaire scores including energy, pain degrees, emotional changes, sleep quality, social life adaptability and somatic activity ability and others(P<0.05). Conclusion: PenQiangYan decoction retention enema and small dosage of fleroxacin could effectively improve clinical symptoms of the patient, reduce therapeutic adverse reaction and improve quality of life.
Objective: To observe clinical effects of PenQiangYan decoction retention enema and small dosage of fleroxacin in treating chronic pelvic inflammation(CPI). Methods: Eighty patients were randomized into the observation group and the control group, 40 cases each group. The control group took fleroxacin, once each day,0.4 g each time, once each day, in the morning; the observation group were treated by PenQiangYan decoction retention enema and half of the dosage of fleroxacin, Nottingham health questionnaire score, the incidence of adverse reaction and the mitigation time of clinical symptoms were compared between both groups. Results: The observation group was earlier than the control group in the mitigation time of clinical symptoms including lumbosacral pain, leukorrhagia, smell and yellow, physical fatigue and feeble, the difference had statistical meaning(P<0.05). The incidence of adverse reaction in the observation group was 7.5%, lower than 30.0% of the control group, and the difference showed statistical meaning(P <0.05). The difference had statistical meaning in the comparisons of Nottingham health questionnaire scores including energy, pain degrees, emotional changes, sleep quality, social life adaptability and somatic activity ability and others(P<0.05). Conclusion: PenQiangYan decoction retention enema and small dosage of fleroxacin could effectively improve clinical symptoms of the patient, reduce therapeutic adverse reaction and improve quality of life.
引文
[1]施慧,王靓,龙子江,等.桂枝茯苓胶囊保留灌肠治疗慢性盆腔炎的实验研究[J].实验中医药学,2013,14(1):11-13.
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[12]梁娜,张阳,刘瑞芬,等.综合疗法对慢性盆腔炎患者生存质量影响的研究[J].辽宁中医杂志,2013,38(10):1946-1947.
[13]卢彩珠,罗秀霞.左氧氟沙星与替硝唑联合保留灌肠治疗慢性盆腔炎的临床观察[J].中外医学研究,2013,11(5):40-41.
[14]潘敏.中医治疗慢性盆腔炎进展[J].实用中医药杂志,2014,30(4):371-372.
[15]白秀萍,尹姝心,张兰华.中药盆腔炎汤剂保留灌肠治疗慢性盆腔炎的临床观察[J].实用中西医结合临床,2013,10(1):51-52.
[16]贾春霞,朱志红.中药保留灌肠在妇科病中的应用[J].中国乡村医药杂志,2014,18(4):78-79.
[17]陶剑飞,卢兴宏.中药内服外用治疗慢性盆腔炎35例[J].辽宁中医杂志,2014,38(7):1389-1390.
[2]徐金凤,贾雪玲.传统与改良保留灌肠法治疗慢性盆腔炎的效果比较[J].慢性病学杂志,2014,15(6):500-501.
[3]王秀宝,陈月玲,张季青,等.不同插管深度对中药保留灌肠治疗盆腔炎性疾病临床疗效的影响[J].中国中医药信息杂志,2013,20(4):78-79.
[4]符琼娥,符晶莹.奥硝唑胶囊配合盆炎汤保留灌肠加腹部热疗治疗宫外孕术后盆腔炎的临床分析[J].中国妇幼保健,2014,29(7):1059-1061.
[5]陆珏瑾.盆腔炎性疾病的病因及诊治进展[J].中国优生优育,2014,20(5):337-340.
[6]陈月玲,张季青,王秀宝,等.盆炎灌肠方对盆腔炎性疾病的镇痛作用及对免疫功能的影响[J].中医中药,2013,10(6):88-90.
[7]谢辛,苟文丽.妇产科学[M].北京:人民卫生出版社,2013:171.
[8]史明娟.中药保留灌肠配合离子导入治疗盆腔炎40例疗效观察[J].西部中医药,2012,25(8):94-95.
[9]言兰枝.中药保留灌肠结合下腹部中药熨烫治疗盆腔炎性疾病后遗症例[J].河南中医,2013,33(10):1817-1818.
[10]杨安娜.中药保留灌肠联合中药熨烫治疗盆腔炎的临床研究[J].中医学报,2013,28(7):1032-1033.
[11]康玉英.中药保留灌肠加中药离子导入治疗盆腔炎性疾病后遗症的护理[J].中国医药指南,2012,10(6):274-276.
[12]梁娜,张阳,刘瑞芬,等.综合疗法对慢性盆腔炎患者生存质量影响的研究[J].辽宁中医杂志,2013,38(10):1946-1947.
[13]卢彩珠,罗秀霞.左氧氟沙星与替硝唑联合保留灌肠治疗慢性盆腔炎的临床观察[J].中外医学研究,2013,11(5):40-41.
[14]潘敏.中医治疗慢性盆腔炎进展[J].实用中医药杂志,2014,30(4):371-372.
[15]白秀萍,尹姝心,张兰华.中药盆腔炎汤剂保留灌肠治疗慢性盆腔炎的临床观察[J].实用中西医结合临床,2013,10(1):51-52.
[16]贾春霞,朱志红.中药保留灌肠在妇科病中的应用[J].中国乡村医药杂志,2014,18(4):78-79.
[17]陶剑飞,卢兴宏.中药内服外用治疗慢性盆腔炎35例[J].辽宁中医杂志,2014,38(7):1389-1390.