Keratron角膜超声测厚仪和Pentacam测量内蒙古地区屈光不正患者中央角膜厚度的差异性研究
|
摘要
目的比较Keratron角膜超声测厚仪与Pentacam测量内蒙古地区屈光不正患者中央角膜厚度的差异,为内蒙古地区屈光不正患者角膜生物力学相关参数分析提供参考,为准分子手术安全性提供依据。方法随机抽取2015年3月～2016年11月在内蒙古医科大学附属医院近视眼激光治疗中心就诊的屈光不正患者140例,其中蒙古族70例(137眼),汉族70例(140眼)。应用Pentacam和Keratron角膜超声测厚仪测量内蒙古地区蒙古族及汉族屈光不正患者中央角膜厚度,并对测量结果进行数据分析。结果 Keratron角膜超声测厚仪所测蒙古族患者的中央角膜厚度为(549.02±33.55)μm,汉族屈光不正患者的中央角膜厚度为(575.92±37.19)μm;Pentacam所测蒙古族屈光不正患者的中央角膜厚度为(538.34±32.61)μm,汉族屈光不正患者的中央角膜厚度为(557.75±31.99)μm。同一仪器测量不同民族中央角膜厚度比较,同一民族不同仪器中央角膜厚度比较,差异均有高度统计学意义(P <0.01)。结论 Pentacam测量中央角膜厚度较Keratron角膜超声测厚仪薄,研究对象中蒙古族屈光不正患者中央角膜厚度较汉族患者薄。
Objective To compare the difference in central corneal thickness measurement of patients with refractive error in Inner Mongolia Region performed with Keratron corneal ultrasound thickness gauge and Pentacam, and provide reference for the analysis of corneal biomechanical parameters and basis for the safety of excimer laser surgery. Methods From March 2015 to November 2016, 140 patients with refractive error were randomly selected from the Myopia Laser Treatment Center of the Affiliated Hospital of Inner Mongolia Medical University, including 70 Mongolian(137 eyes)and 70 Han(140 eyes) patients. Pentacam and Keratron corneal ultrasound thickness gauge were used to measure the central corneal thickness of Mongolian and Han patients with refractive error in Inner Mongolia Region, and the data of the measurement results were analyzed. Results The central corneal thickness of Mongolians patients was(549.02±33.55) μm,that of Han patients was(575.92±37.19) μm measured with Keratron, the central corneal thickness of Mongolians patients was(538.34±32.61) μm, that of Han patients was(557.75±31.99) μm measured with Pentacam, there were high statistically significant differences in central corneal thickness for the different nationalities measured with same equipment and for the same nationality measured with different equipment(P < 0.01). Conclusion The thickness of the central cornea measured by Pentacam was thinner than that of Keratron corneal ultrasound thickness gauge, and the thickness of the central cornea of the Mongolian patients in the study objects is thinner than that of the Han patients.
Objective To compare the difference in central corneal thickness measurement of patients with refractive error in Inner Mongolia Region performed with Keratron corneal ultrasound thickness gauge and Pentacam, and provide reference for the analysis of corneal biomechanical parameters and basis for the safety of excimer laser surgery. Methods From March 2015 to November 2016, 140 patients with refractive error were randomly selected from the Myopia Laser Treatment Center of the Affiliated Hospital of Inner Mongolia Medical University, including 70 Mongolian(137 eyes)and 70 Han(140 eyes) patients. Pentacam and Keratron corneal ultrasound thickness gauge were used to measure the central corneal thickness of Mongolian and Han patients with refractive error in Inner Mongolia Region, and the data of the measurement results were analyzed. Results The central corneal thickness of Mongolians patients was(549.02±33.55) μm,that of Han patients was(575.92±37.19) μm measured with Keratron, the central corneal thickness of Mongolians patients was(538.34±32.61) μm, that of Han patients was(557.75±31.99) μm measured with Pentacam, there were high statistically significant differences in central corneal thickness for the different nationalities measured with same equipment and for the same nationality measured with different equipment(P < 0.01). Conclusion The thickness of the central cornea measured by Pentacam was thinner than that of Keratron corneal ultrasound thickness gauge, and the thickness of the central cornea of the Mongolian patients in the study objects is thinner than that of the Han patients.
引文
[1] Park SH,Choi SK,Lee D,et al. Corneal thickness measurement using Orbscan,Pentacam,Galilei,and ultrasound in normal and post-femtosecond laser in situ keratomileusis eyes[J]. Cornea,2012,31(9):978-982.
[2] Randleman JB,Lynn MJ,Perez-Straziota CE,et al. Comparison of central and peripheral corneal thickness measurements with scanning-slit,Scheimpflug and Fourierdomain ocular coherence tomography[J]. Br J Ophthalmol,2015,99(9):1176-1181.
[3] Rio-Cristobal A,Martin R. Corneal assessment technologies:current status[J]. Surv Ophthalmol,2014,59(6):599-614.
[4] Yap TE,Archer TJ,Gobbe M,et al. Comparison of central corneal thickness between fourier-domain oct,very highfrequency digital ultrasound,and Scheimpflug imaging systems[J]. J Refract Surg,2016,32(2):110-116.
[5] Maloca PM,Studer HP,Ambrósio R,et al. Interdevice variability of central corneal thickness measurement[J]. PLoS One,2018,13(9):e0203884.
[6] Feizi S,Jafarinasab MR,Karimian F,et al. Central and peripheral corneal thickness measurement in normal and keratoconic eyes using three corneal pachymeters[J]. J Ophthalmic Vis Res,2014,9(3):296-304.
[7] Yildirim Y,Olcucu O,Agca A,et al. Topographic and biomechanical evaluation of corneas in patients with ocular rosacea[J]. Cornea,2015,34(3):313-317.
[8] Beutelspacher SC,Serbecic N,Scheuerle AF. Assessment of central corneal thickness using OCT,ultrasound,optical low coherence reflectometry and Scheimpflug pachymetry[J].Eur J Ophthalmol,2011,21(2):132-137.
[9]王霁雪,吴荒,杨隆艳,等. Orbscan-Ⅱ、Pentacam及超声测厚仪角膜厚度测量值的比较[J].中华眼视光学与视觉科学杂志,2010,12(1):64-67.
[10]王淑荣,肖鹏柁,刘鑫,等.角膜厚度测量影响因素研究进展[J].中国实验诊断学,2015,19(10):1805-1808.
[11]李坤,陆蓓,崇晓霞,等.麻醉剂和泪膜对健康人角膜厚度的影响[J].眼视光学杂志,2004,6(4):244-246.
[12]王华玲,赖江龙.不同表面麻醉剂在眼科A超检查中对角膜上皮的损伤研究[J].国际眼科杂志,2014,20(11):29-34.
[13] Niimi J,Tan B,Chang J,et al. Diurnal Pattern of Tear Osmolarity and Its Relationship to Corneal Thickness and Deswelling[J]. Cornea,2013,32(10):1305-1310.
[14] Zhao HX,Zhang L,Guan WY,et al. Difference in normal corneal thickness and curvature between Mongolian and Han nationalities[J]. Int J Ophthalmol,2015,8(2):399-402.
[15] Naderan M,Shoar S,Naderan M,et al. Comparison of corneal measurements in keratoconic eyes using rotating Scheimpflug camera and scanning-slit topography[J]. Int J Ophthalmol,2015,8(2):275-280.
[16] Wongchaisuwat N,Metheetrairat A,Chonpimai P,et al.Comparison of central corneal thickness measurements in corneal edema using ultrasound pachymetry,Visante anterior-segment optical coherence tomography,Cirrus optical coherence tomography,and Pentacam Scheimpflug camera tomography[J]. Clin Ophthalmol,2018,25(12):1865-1873.
[17] Nassiri N,Sheibani K,Safi S,et al. Central corneal thickness in highly myopic eyes:inter-device agreement of ultrasonic pachymetry,pentacamand orbscanⅡbefore and after photorefractive keratectomy[J]. J Ophthalmic Vis Res,2014,9(1):14-21.
[18] Nemeth G,Hassan Z,Szalai E,et al. Anterior segment parameters measured with 2 optical devices compared to ultrasonic data[J]. Eur J Ophthalmol,2013,23(2):177-182.
[19] Faria-Correia F,Ramos I,Valbon B,et al. Scheimpflugbased tomography and biomechanical assessment in pressure-induced stromal keratopathy[J]. J Refract Surg,2013,29(5):356-358.
[20] Sedaghat MR,Daneshvar R,Kargozar A,et al. Comparison of central corneal thickness measurement usingultrasonic pachymetry,rotating Scheimpflug camera,and scanning-slit topography[J]. Am J Ophthalmol,2010,150(6):780-789.
[21]郝更生,曾莉,李玉茹,等.Pentacam系统与A超角膜测厚仪测量中央角膜厚度的一致性和重复性[J].中华眼科杂志,2011,47(2):142-145.
[2] Randleman JB,Lynn MJ,Perez-Straziota CE,et al. Comparison of central and peripheral corneal thickness measurements with scanning-slit,Scheimpflug and Fourierdomain ocular coherence tomography[J]. Br J Ophthalmol,2015,99(9):1176-1181.
[3] Rio-Cristobal A,Martin R. Corneal assessment technologies:current status[J]. Surv Ophthalmol,2014,59(6):599-614.
[4] Yap TE,Archer TJ,Gobbe M,et al. Comparison of central corneal thickness between fourier-domain oct,very highfrequency digital ultrasound,and Scheimpflug imaging systems[J]. J Refract Surg,2016,32(2):110-116.
[5] Maloca PM,Studer HP,Ambrósio R,et al. Interdevice variability of central corneal thickness measurement[J]. PLoS One,2018,13(9):e0203884.
[6] Feizi S,Jafarinasab MR,Karimian F,et al. Central and peripheral corneal thickness measurement in normal and keratoconic eyes using three corneal pachymeters[J]. J Ophthalmic Vis Res,2014,9(3):296-304.
[7] Yildirim Y,Olcucu O,Agca A,et al. Topographic and biomechanical evaluation of corneas in patients with ocular rosacea[J]. Cornea,2015,34(3):313-317.
[8] Beutelspacher SC,Serbecic N,Scheuerle AF. Assessment of central corneal thickness using OCT,ultrasound,optical low coherence reflectometry and Scheimpflug pachymetry[J].Eur J Ophthalmol,2011,21(2):132-137.
[9]王霁雪,吴荒,杨隆艳,等. Orbscan-Ⅱ、Pentacam及超声测厚仪角膜厚度测量值的比较[J].中华眼视光学与视觉科学杂志,2010,12(1):64-67.
[10]王淑荣,肖鹏柁,刘鑫,等.角膜厚度测量影响因素研究进展[J].中国实验诊断学,2015,19(10):1805-1808.
[11]李坤,陆蓓,崇晓霞,等.麻醉剂和泪膜对健康人角膜厚度的影响[J].眼视光学杂志,2004,6(4):244-246.
[12]王华玲,赖江龙.不同表面麻醉剂在眼科A超检查中对角膜上皮的损伤研究[J].国际眼科杂志,2014,20(11):29-34.
[13] Niimi J,Tan B,Chang J,et al. Diurnal Pattern of Tear Osmolarity and Its Relationship to Corneal Thickness and Deswelling[J]. Cornea,2013,32(10):1305-1310.
[14] Zhao HX,Zhang L,Guan WY,et al. Difference in normal corneal thickness and curvature between Mongolian and Han nationalities[J]. Int J Ophthalmol,2015,8(2):399-402.
[15] Naderan M,Shoar S,Naderan M,et al. Comparison of corneal measurements in keratoconic eyes using rotating Scheimpflug camera and scanning-slit topography[J]. Int J Ophthalmol,2015,8(2):275-280.
[16] Wongchaisuwat N,Metheetrairat A,Chonpimai P,et al.Comparison of central corneal thickness measurements in corneal edema using ultrasound pachymetry,Visante anterior-segment optical coherence tomography,Cirrus optical coherence tomography,and Pentacam Scheimpflug camera tomography[J]. Clin Ophthalmol,2018,25(12):1865-1873.
[17] Nassiri N,Sheibani K,Safi S,et al. Central corneal thickness in highly myopic eyes:inter-device agreement of ultrasonic pachymetry,pentacamand orbscanⅡbefore and after photorefractive keratectomy[J]. J Ophthalmic Vis Res,2014,9(1):14-21.
[18] Nemeth G,Hassan Z,Szalai E,et al. Anterior segment parameters measured with 2 optical devices compared to ultrasonic data[J]. Eur J Ophthalmol,2013,23(2):177-182.
[19] Faria-Correia F,Ramos I,Valbon B,et al. Scheimpflugbased tomography and biomechanical assessment in pressure-induced stromal keratopathy[J]. J Refract Surg,2013,29(5):356-358.
[20] Sedaghat MR,Daneshvar R,Kargozar A,et al. Comparison of central corneal thickness measurement usingultrasonic pachymetry,rotating Scheimpflug camera,and scanning-slit topography[J]. Am J Ophthalmol,2010,150(6):780-789.
[21]郝更生,曾莉,李玉茹,等.Pentacam系统与A超角膜测厚仪测量中央角膜厚度的一致性和重复性[J].中华眼科杂志,2011,47(2):142-145.