补肾活血法干预卵巢储备功能的研究近况
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摘要
[目的]探讨补肾活血法改善卵巢储备功能的疗效及作用机制,为临床治疗提供理论依据。[方法]检索近年来补肾活血法干预卵巢早衰及卵巢储备功能下降的相关文献,从理论研究、临床研究及实验研究3个方面,探讨补肾活血法改善卵巢储备功能的疗效及作用机制。[结果]补肾活血法在改善卵巢储备功能上疗效确切。[结论]近年来补肾活血法改善卵巢功能研究取得进展,对作用机制有较为深入的阐明,但仍需进一步深入地探索和研究。
[Objective] To investigate Bushenhuoxue method to improve the effect and mechanism of ovarian reserve, providing a theoretical basis for clinical treatment. [Methods] The intervention method to retrieve recent Bushenhuoxue premature ovarian failure and decreased ovarian reserve related literature, from theoretical research, clinical research and experimental study three aspects discussed Bushenhuoxue method to improve the effect and mechanism of ovarian reserve. [Results] Invigorating kidney on improving the exact effect of ovarian reserve. [Conclusion] In recent years Bushenhuoxue method research progress in improving ovarian function, mechanism of action has a more in-depth elucidation, but further in-depth exploration and research are still needed.
[Objective] To investigate Bushenhuoxue method to improve the effect and mechanism of ovarian reserve, providing a theoretical basis for clinical treatment. [Methods] The intervention method to retrieve recent Bushenhuoxue premature ovarian failure and decreased ovarian reserve related literature, from theoretical research, clinical research and experimental study three aspects discussed Bushenhuoxue method to improve the effect and mechanism of ovarian reserve. [Results] Invigorating kidney on improving the exact effect of ovarian reserve. [Conclusion] In recent years Bushenhuoxue method research progress in improving ovarian function, mechanism of action has a more in-depth elucidation, but further in-depth exploration and research are still needed.
引文
[1]熊婷婷,黄丽.吴克明教授运用补肾活血法治疗卵巢早衰[J].吉林中医药,2013,33(9):884-885.
[2]陈春晓.卵巢储备功能低下病机探讨[J].山西中医,2013,29(10):61-62.
[3]李珺晔.从中药运用探讨卵巢早衰病机特点[J].长春中医药大学学报,2013,29(3):413-414.
[4]李杏杏.免疫性卵巢早衰的中西医病机研究进展[J].中医学报,2013,28(6):879-881.
[5]王玉东.补肾活血促卵泡发育的临床研究[J].山东中医药大学学报,2001,26(3):207-209.
[6]夏天,金季玲.补肾调冲法治疗卵巢早衰的临床及实验研究进展[J].国医论坛,2010,25(4):51-53.
[7]种丽群.补肾活血化淤法治疗卵巢早衰24例[J].实用中医药杂志,2006,22(11):675.
[8]黄艳辉,梁雪芳.补肾活血法对卵巢子宫内膜异位囊肿剔除术后卵巢储备功能的干预作用[J].广州中医药大学学报,2012,29(3):232-235.
[9]李佶,郑锦.滋肾活血法治疗卵巢储备功能下降50例临床观察[J].中国中西医结合杂志,2011,31(10):1429-1430.
[10]王利平.补肾祛瘀法治疗卵巢功能早衰48例[J].陕西中医,2010,31(3):264-265.
[11]董莉,姜琳.补肾活血方对卵巢早衰患者血清FSH、LH、E2及PRL的影响[J].上海中医药杂志,2007,41(11):48-49.
[12]张文红.滋肾益经活血汤治疗卵巢早衰患者50例临床观察[J].世界中西医结合杂志,2012,7(8):670-675.
[13]许小凤,谈勇.补肾活血中药对卵巢储备功能的影响[J].江苏中医药,2007,39(2):18-20.
[14]侯爱贞,王利平.补肾活血汤治疗卵巢早衰临床研究[J].河南中医,2014,34(2):314-316.
[15]钟丽群.补肾活血化淤法治疗卵巢早衰24例[J].实用中医药杂志,2006,22(11):675.
[16]伍朝霞,李春娣.益肾活血汤口服配合按摩治疗卵巢早衰59例[J].辽宁中医杂志,2010,37(8):1533-1534.
[17]郑纯,余娜.补肾调肝活血方治疗卵巢早衰117例临床观察[J].湖南中医杂志,2012,28(2):17-18.
[18]胡兴文,王维鹏.补肾活血方对小鼠卵泡刺激素及其受体mRNA表达的影响[J].中国免疫学杂志,2010,26(11):1003-1006.
[19]ZhengW,MagidMS,KramerEE.Follicle一stimulating hormone receptor is expressed in human ovarian surface epithelium and falloPian tube[J].Am J Pathol,1996,(148):47.
[20]刘慧萍.补肾活血方对免疫性卵巢早衰小鼠卵泡凋亡相关蛋白的影响[J].湖南中医药大学学报,2012,32(5):28-31.
[21]刘慧萍,雷磊.补肾活血方对免疫性卵巢早衰小鼠外周血抗透明带抗体的影响[J].甘肃中医学院学报,2010,27(3):9-11.
[22]刘慧萍,尤昭玲.补肾活血方对免疫性卵巢早衰小鼠卵泡凋亡调控基因(Bcl-2/Bax)蛋白的影响[J].中华中医药学刊,2010,28(5):1036-1038.
[23]许小凤,谈勇.补肾活血中药对雷公藤致卵巢储备下降大鼠颗粒细胞凋亡的影响[J].中国实验方剂学杂志,2009,38(12):123-125.
[24]许小凤.补肾活血法对卵巢储备功能低下干预的效应机理研究与临床证治探讨[D].南京:南京中医药大学,2010:24-29.
[25]李芳,孙兰,唐传玲.补肾活血方对免疫性卵巢早衰小鼠的影响[J].中国实验方剂学杂志,2011,17(16):137-140.
[2]陈春晓.卵巢储备功能低下病机探讨[J].山西中医,2013,29(10):61-62.
[3]李珺晔.从中药运用探讨卵巢早衰病机特点[J].长春中医药大学学报,2013,29(3):413-414.
[4]李杏杏.免疫性卵巢早衰的中西医病机研究进展[J].中医学报,2013,28(6):879-881.
[5]王玉东.补肾活血促卵泡发育的临床研究[J].山东中医药大学学报,2001,26(3):207-209.
[6]夏天,金季玲.补肾调冲法治疗卵巢早衰的临床及实验研究进展[J].国医论坛,2010,25(4):51-53.
[7]种丽群.补肾活血化淤法治疗卵巢早衰24例[J].实用中医药杂志,2006,22(11):675.
[8]黄艳辉,梁雪芳.补肾活血法对卵巢子宫内膜异位囊肿剔除术后卵巢储备功能的干预作用[J].广州中医药大学学报,2012,29(3):232-235.
[9]李佶,郑锦.滋肾活血法治疗卵巢储备功能下降50例临床观察[J].中国中西医结合杂志,2011,31(10):1429-1430.
[10]王利平.补肾祛瘀法治疗卵巢功能早衰48例[J].陕西中医,2010,31(3):264-265.
[11]董莉,姜琳.补肾活血方对卵巢早衰患者血清FSH、LH、E2及PRL的影响[J].上海中医药杂志,2007,41(11):48-49.
[12]张文红.滋肾益经活血汤治疗卵巢早衰患者50例临床观察[J].世界中西医结合杂志,2012,7(8):670-675.
[13]许小凤,谈勇.补肾活血中药对卵巢储备功能的影响[J].江苏中医药,2007,39(2):18-20.
[14]侯爱贞,王利平.补肾活血汤治疗卵巢早衰临床研究[J].河南中医,2014,34(2):314-316.
[15]钟丽群.补肾活血化淤法治疗卵巢早衰24例[J].实用中医药杂志,2006,22(11):675.
[16]伍朝霞,李春娣.益肾活血汤口服配合按摩治疗卵巢早衰59例[J].辽宁中医杂志,2010,37(8):1533-1534.
[17]郑纯,余娜.补肾调肝活血方治疗卵巢早衰117例临床观察[J].湖南中医杂志,2012,28(2):17-18.
[18]胡兴文,王维鹏.补肾活血方对小鼠卵泡刺激素及其受体mRNA表达的影响[J].中国免疫学杂志,2010,26(11):1003-1006.
[19]ZhengW,MagidMS,KramerEE.Follicle一stimulating hormone receptor is expressed in human ovarian surface epithelium and falloPian tube[J].Am J Pathol,1996,(148):47.
[20]刘慧萍.补肾活血方对免疫性卵巢早衰小鼠卵泡凋亡相关蛋白的影响[J].湖南中医药大学学报,2012,32(5):28-31.
[21]刘慧萍,雷磊.补肾活血方对免疫性卵巢早衰小鼠外周血抗透明带抗体的影响[J].甘肃中医学院学报,2010,27(3):9-11.
[22]刘慧萍,尤昭玲.补肾活血方对免疫性卵巢早衰小鼠卵泡凋亡调控基因(Bcl-2/Bax)蛋白的影响[J].中华中医药学刊,2010,28(5):1036-1038.
[23]许小凤,谈勇.补肾活血中药对雷公藤致卵巢储备下降大鼠颗粒细胞凋亡的影响[J].中国实验方剂学杂志,2009,38(12):123-125.
[24]许小凤.补肾活血法对卵巢储备功能低下干预的效应机理研究与临床证治探讨[D].南京:南京中医药大学,2010:24-29.
[25]李芳,孙兰,唐传玲.补肾活血方对免疫性卵巢早衰小鼠的影响[J].中国实验方剂学杂志,2011,17(16):137-140.