柴芍抗松汤治疗老年原发性骨质疏松症伴抑郁39例
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摘要
目的:观察柴芍抗松汤治疗老年原发性骨质疏松症伴抑郁的临床疗效。方法:将78例患者随机分为观察组和对照组,每组39例。观察组口服柴芍抗松汤,对照组口服阿仑膦酸钠片(福善美),2组均连续治疗4个疗程。观察2组老年原发性骨质疏松症、抑郁障碍临床疗效及老年抑郁量表(GDS)评分。结果:老年原发性骨质疏松症总有效率观察组为92.3%,对照组为84.6%,2组比较差异有统计学意义(P<0.05);抑郁障碍总有效率观察组为89.7%,对照组为74.4%,2组比较差异有统计学意义(P<0.05)。2组随着治疗时间的增加,GDS评分越低;相同时间点2组比较,差异有统计学意义(P<0.05)。结论:采用柴芍抗松汤治疗老年原发性骨质疏松伴抑郁症患者临床疗效显著。
Objective: To observe clinical effects of ChaiShao KangSong decoction in treating senile patients suffering primary osteoporosis accompanying depression. Methods: All 78 patients were randomly allocated to the observation group and the control group, 39 cases each group. The observation group took ChaiShao KangSong decoction, and the control group Alendronate sodium tablets, both groups were treated for four courses consecutively.Geriatric depression scale(GDS) and clinical effects of depression disorder of the patients with primary osteoporosis were observed. Results: Total effective rate of senile patients suffering primary osteoporosis in the observation group was 92.3%, higher than 84.6% of the control group, and the difference had statistical meaning(P <0.05); total effective rate of depressive disorder in the observation group was 89.7%, higher than 74.4% of the control group, and the difference had statistical meaning in the comparisons of clinical effects(P <0.05). As the therapeutic time increased in both group, GDS scales became lower; the difference showed statistical meaning in the comparisons between both groups at the same time point(P<0.05). Conclusion: ChaiShao KangSong decoction is effective in treating the senile patients suffering primary osteoporosis complicated with depression.
Objective: To observe clinical effects of ChaiShao KangSong decoction in treating senile patients suffering primary osteoporosis accompanying depression. Methods: All 78 patients were randomly allocated to the observation group and the control group, 39 cases each group. The observation group took ChaiShao KangSong decoction, and the control group Alendronate sodium tablets, both groups were treated for four courses consecutively.Geriatric depression scale(GDS) and clinical effects of depression disorder of the patients with primary osteoporosis were observed. Results: Total effective rate of senile patients suffering primary osteoporosis in the observation group was 92.3%, higher than 84.6% of the control group, and the difference had statistical meaning(P <0.05); total effective rate of depressive disorder in the observation group was 89.7%, higher than 74.4% of the control group, and the difference had statistical meaning in the comparisons of clinical effects(P <0.05). As the therapeutic time increased in both group, GDS scales became lower; the difference showed statistical meaning in the comparisons between both groups at the same time point(P<0.05). Conclusion: ChaiShao KangSong decoction is effective in treating the senile patients suffering primary osteoporosis complicated with depression.
引文
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[9]黄火剑.补肾益心片对原发性高血压患者的治疗作用及其机制研究[D].广州:广州中医药大学,2011.
[10]谭新,刘芳,叶竹,等.近五年中医药治疗骨质疏松文献分析[J].中国骨质疏松杂志,2011,17(4):359-363.
[2]王忠志.独活寄生汤治疗老年性骨质疏松症48例[J].河南中医,2014,39(8):1612-1613.
[3]邹立,黄宏兴,叶竹,等.补肾壮骨冲剂与阿仑膦酸钠治疗老年男性骨质疏松症疗效比较[J].华南国防医学杂志,2013,32(10):730-734.
[4]苏俊声.从肾防治糖皮质激素性骨质疏松症的理论与临床研究[D].广州:广州中医药大学,2013.
[5]郭菡.补肾益髓埋线法治疗绝经后骨质疏松大鼠的肠钙机制研究[D].广州:广州中医药大学,2013.
[6]胥少汀,葛宝丰.实用骨科[M].北京:人民军医出版社,2005:131.
[7]彭聃龄.普通心理学[M].北京:北京师范大学出版社,2012:173.
[8]马晓薇.针灸督脉为主治疗老年性骨质疏松症临床研究[J].求医问药:下半月,2012,28(7):387-389.
[9]黄火剑.补肾益心片对原发性高血压患者的治疗作用及其机制研究[D].广州:广州中医药大学,2011.
[10]谭新,刘芳,叶竹,等.近五年中医药治疗骨质疏松文献分析[J].中国骨质疏松杂志,2011,17(4):359-363.