阿司匹林联合硫酸氢氯吡格雷治疗脑梗死的临床价值
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摘要
目的探讨阿司匹林联合硫酸氢氯吡格雷口服治疗脑梗死的临床价值。方法选取我院2015年1月—2018年1月收治的106例脑梗死患者作为研究对象,以随机数字法,将其分成两组。每组各53例,其中,对照组采用阿斯匹林药物治疗,观察组采用阿司匹林联合硫酸氢氯吡格雷口服治疗,比较两组患者的临床疗效。结果治疗后,观察组患者的治疗总有效率为96.23%,对照组患者治疗的总有效率为84.91%,两组对比,观察组更优,差异具有统计学意义(P <0.05);治疗前,两组患者的神经功能缺损评分比较,差异无统计学意义(P> 0.05);治疗后,观察组优于对照组,差异具有统计学意义(P <0.05);观察组的不良反应总发生率为3.77%,对照组为13.21%,两组对比,观察组更优,差异具有统计学意义(P <0.05)。结论在临床医学中,阿司匹林联合硫酸氢氯吡格雷口服治疗脑梗死效果极佳,有良好的临床应用价值。
Objective To probe into the clinical value of aspirin combined with clopidogrel sulfate in the treatment of cerebral infarction. Methods 106 patients with cerebral infarction admitted to our hospital from January 2015 to January 2018 were selected as the research objects. They were divided into two groups by random number method. There were 53 cases in each group. The control group was treated with aspirin. The observation group was treated with aspirin combined with clopidogrel bisulfate orally. The clinical effects of the two groups were compared. Results After treatment,the total effective rate was 96.23% in the observation group and 84.91% in the control group. Compared with the two groups, the observation group was better and the difference was statistically significant(P < 0.05). Before treatment, there was no significant difference in neurological deficit scores between the two groups(P > 0.05). After treatment, the observation group was better than the control group(P < 0.05); the total incidence of adverse reactions was 3.77% in the observation group and 13.21% in the control group, and the two groups were better than the observation group(P <0.05). Conclusion In clinical medicine, the effects of aspirin combined with clopidogrel sulfate in the treatment of cerebral infarction are good,which it has good clinical application value.
Objective To probe into the clinical value of aspirin combined with clopidogrel sulfate in the treatment of cerebral infarction. Methods 106 patients with cerebral infarction admitted to our hospital from January 2015 to January 2018 were selected as the research objects. They were divided into two groups by random number method. There were 53 cases in each group. The control group was treated with aspirin. The observation group was treated with aspirin combined with clopidogrel bisulfate orally. The clinical effects of the two groups were compared. Results After treatment,the total effective rate was 96.23% in the observation group and 84.91% in the control group. Compared with the two groups, the observation group was better and the difference was statistically significant(P < 0.05). Before treatment, there was no significant difference in neurological deficit scores between the two groups(P > 0.05). After treatment, the observation group was better than the control group(P < 0.05); the total incidence of adverse reactions was 3.77% in the observation group and 13.21% in the control group, and the two groups were better than the observation group(P <0.05). Conclusion In clinical medicine, the effects of aspirin combined with clopidogrel sulfate in the treatment of cerebral infarction are good,which it has good clinical application value.
引文
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[9]冯文,初丽,马红梅,等.针对性护理配合对腔镜甲状腺切除术中相关并发症的影响[J].实用临床医药杂志,2017,21(18):63-65.
[10]王江华,崔雅清.手术室护理干预对甲状腺手术患者心理状态及生命体征的效果[J].实用临床医药杂志,2017,21(14):72-74.
[11]钟敏,蔡珺,何敏芝,等.术中神经监测在复杂性甲状腺手术中的应用及护理体会[J].浙江医学,2017,39(11):928-929.
[12]王勇,孙毅群,杨玉和,等.甲状腺次全切除术术后感染相关因素分析[J].中华医院感染学杂志,2017,27(9):2032-2034.
[2]梁茜茜,张庆,李莉,等.阿司匹林联合氯吡格雷治疗急性脑梗死的临床研究[J].中国临床药理学杂志,2016,32(16):1446-1448.
[3]韦宁.氯吡格雷联合阿司匹林治疗进展型脑梗死的疗效及对神经和凝血功能的影响[J].蚌埠医学院学报,2013,38(7):844-846.
[4]郭静.阿司匹林、硫酸氢氯吡格雷联合膳食干预治疗脑梗死患者的临床效果[J].中国医药导报,2018,15(8):72-75.
[5]叶宝惠,张连玉,杨金花.甲状腺手术患者的手术室护理分析[J].基层医学论坛, 2017,21(24):3291-3293.
[6]张波.探讨阿斯匹林联合硫酸氢氯吡格雷口服治疗脑梗塞的有效性及安全性[J].医药前沿,2016,22(4):54-55.
[7]王振兴.阿斯匹林联合硫酸氢氯吡格雷口服治疗脑梗塞的有效性和安全性观察[J].世界最新医学信息文摘(连续型电子期刊),2017,17(28):746-746.
[8]毛云海,刘瑶,余文兴,等.手术室个性化舒适护理在甲状腺癌手术患者中的应用[J].肿瘤预防与治疗,2017,30(3):191-197.
[9]冯文,初丽,马红梅,等.针对性护理配合对腔镜甲状腺切除术中相关并发症的影响[J].实用临床医药杂志,2017,21(18):63-65.
[10]王江华,崔雅清.手术室护理干预对甲状腺手术患者心理状态及生命体征的效果[J].实用临床医药杂志,2017,21(14):72-74.
[11]钟敏,蔡珺,何敏芝,等.术中神经监测在复杂性甲状腺手术中的应用及护理体会[J].浙江医学,2017,39(11):928-929.
[12]王勇,孙毅群,杨玉和,等.甲状腺次全切除术术后感染相关因素分析[J].中华医院感染学杂志,2017,27(9):2032-2034.