五拗汤加味联合头孢噻肟钠治疗老年慢性支气管炎急性加重期疗效观察
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摘要
目的:探讨五拗汤加味联合头孢噻肟治疗老年慢性支气管炎急性加重期的临床疗效。方法:选取2016-2018年笔者所在医院收治的82例老年慢性支气管炎急性加重期患者,随机分为研究组(41例)、对照组(41例)。对照组在头孢噻肟钠基础上口服强力枇杷露进行治疗,研究组在此基础上联合五拗汤进行治疗,治疗1周后观察两组临床疗效及治疗前、后肺功能变化。结果:研究组临床总有效率为97.56%,相较于对照组的87.80%明显更高,差异有统计学意义(P<0.05);治疗前两组FEV1、FVC、PEF等肺功能指标差异无统计学意义(P>0.05),治疗后研究组FEV1、FVC、PEF等指标均显著高于对照组,差异均有统计学意义(P<0.05)。结论:对老年慢性支气管炎患者而言,五拗汤联合头孢噻肟钠是一种理想的治疗方式,可进一步增强临床疗效,改善患者肺功能,促进临床症状及体征的消失,在临床上具有切实可行性及安全性。
Objective:To study the clinical efficacy of modified Wu'Ao Decoction combined with Cefotaxime Sodium in acute exacerbation of chronic bronchitis.Method:A total of 82 elderly patients with acute exacerbation of chronic bronchitis treated from 2016 to 2018 in our hospital were selected.Patients were randomly assigned to two groups,41 cases each group.The control group took Cefotaxime Sodium and Qiangli Pipa syrup,the study group took Wut'Ao Decoction with Cefotaxime Sodium.After 1 w of treatment,the clinical efficacy and pulmonary function were probed.Result:The total effective rate in the study group(97.56%) was significantly higher than 87.80% of control group(P<0.05).Before treatment,there were no significant differences in the pulmonary function indicators of FEV1(Forced Expiratory Volume in the first second),FVC(forced vital capacity) and PEF(peak expiratory flow) between two groups(P>0.05),after treatment,the values of FEV1,FVC and PEF in the study group were significantly higher than control group(P<0.05).Conclusion:The Wu'Ao Decoction combined with Cefotaxime Sodium can better increase the clinical efficacy,improve the pulmonary function and relieve the clinical symptoms and signs.It is practicable,feasible and safe in clinical practice.
Objective:To study the clinical efficacy of modified Wu'Ao Decoction combined with Cefotaxime Sodium in acute exacerbation of chronic bronchitis.Method:A total of 82 elderly patients with acute exacerbation of chronic bronchitis treated from 2016 to 2018 in our hospital were selected.Patients were randomly assigned to two groups,41 cases each group.The control group took Cefotaxime Sodium and Qiangli Pipa syrup,the study group took Wut'Ao Decoction with Cefotaxime Sodium.After 1 w of treatment,the clinical efficacy and pulmonary function were probed.Result:The total effective rate in the study group(97.56%) was significantly higher than 87.80% of control group(P<0.05).Before treatment,there were no significant differences in the pulmonary function indicators of FEV1(Forced Expiratory Volume in the first second),FVC(forced vital capacity) and PEF(peak expiratory flow) between two groups(P>0.05),after treatment,the values of FEV1,FVC and PEF in the study group were significantly higher than control group(P<0.05).Conclusion:The Wu'Ao Decoction combined with Cefotaxime Sodium can better increase the clinical efficacy,improve the pulmonary function and relieve the clinical symptoms and signs.It is practicable,feasible and safe in clinical practice.
引文
[1]孙洪伟,刘雪林,宋春艳,等.五拗汤加味联合头孢噻肟钠治疗老年慢性支气管炎急性加重期疗效观察[J].河北医学,2016,22(4):651-653.
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[4]刘春花,周志愉,孙法莹,等.左氧氟沙星联合润肺膏治疗慢性支气管炎的疗效分析[J].中国药房,2016,27(33):4649-4651.
[5]姜芊竹,孙静,邢露茗,等.清金化痰汤加减治疗痰热郁肺型慢性支气管炎急性发作期的临床研究[J].现代中西医结合杂志,2018,27(2):157-159.
[6]任庆伟.疏风解毒胶囊联合抗生素治疗慢性支气管炎急性加重期临床观察[J].中国中医急症,2016,25(8):1571-1573.
[7]陈一丹,周隽,喻朝宁,等.老年慢性支气管炎合并真菌感染患者的临床治疗[J].中华医院感染学杂志,2016,26(9):1958-1960.
[8]白文梅,王兵,杜丽娟,等.中西医结合治疗慢性支气管炎急性加重期临床观察[J].实用中医药杂志,2017,33(8):927-928.
[9]王林梅.研究痰热清联合头孢呋辛治疗老年慢性支气管炎急性加重期的临床疗效[J].中国继续医学教育,2016,8(15):193-194.
[10]安玉英,张风林,角灿武,等.阿奇霉素联合头孢噻肟钠对肺部感染患者炎性状态的控制效果观察[J].中华医院感染学杂志,2017,27(1):95-97.
[11]王萌嘉,张晓星,王丽哲,等.中西医联合治疗慢性支气管炎的临床观察[J].中国卫生标准管理,2016,7(11):153-155.
[12]苏岚.中西医结合治疗慢性支气管炎急性发作期的临床价值分析[J/OL].中西医结合心血管病电子杂志,2017,5(19):150-151.
[13]崔惠娟.五拗汤加味辅助治疗老年慢性支气管炎急性加重期的疗效观察[J].云南中医中药杂志,2017,38(3):53-54.
[2]白惠芙.中西医结合治疗慢性支气管炎急性发作的临床观察[J].中国中医急症,2015,24(5):881-883.
[3]张振海,李玉华.慢性支气管炎急性加重期的中医临床研究[J/OL].中西医结合心血管病电子杂志,2017,5(20):145.
[4]刘春花,周志愉,孙法莹,等.左氧氟沙星联合润肺膏治疗慢性支气管炎的疗效分析[J].中国药房,2016,27(33):4649-4651.
[5]姜芊竹,孙静,邢露茗,等.清金化痰汤加减治疗痰热郁肺型慢性支气管炎急性发作期的临床研究[J].现代中西医结合杂志,2018,27(2):157-159.
[6]任庆伟.疏风解毒胶囊联合抗生素治疗慢性支气管炎急性加重期临床观察[J].中国中医急症,2016,25(8):1571-1573.
[7]陈一丹,周隽,喻朝宁,等.老年慢性支气管炎合并真菌感染患者的临床治疗[J].中华医院感染学杂志,2016,26(9):1958-1960.
[8]白文梅,王兵,杜丽娟,等.中西医结合治疗慢性支气管炎急性加重期临床观察[J].实用中医药杂志,2017,33(8):927-928.
[9]王林梅.研究痰热清联合头孢呋辛治疗老年慢性支气管炎急性加重期的临床疗效[J].中国继续医学教育,2016,8(15):193-194.
[10]安玉英,张风林,角灿武,等.阿奇霉素联合头孢噻肟钠对肺部感染患者炎性状态的控制效果观察[J].中华医院感染学杂志,2017,27(1):95-97.
[11]王萌嘉,张晓星,王丽哲,等.中西医联合治疗慢性支气管炎的临床观察[J].中国卫生标准管理,2016,7(11):153-155.
[12]苏岚.中西医结合治疗慢性支气管炎急性发作期的临床价值分析[J/OL].中西医结合心血管病电子杂志,2017,5(19):150-151.
[13]崔惠娟.五拗汤加味辅助治疗老年慢性支气管炎急性加重期的疗效观察[J].云南中医中药杂志,2017,38(3):53-54.