老年脑梗死患者心肌酶水平与脑梗死严重程度的临床意义分析
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摘要
目的探讨高龄老年脑梗死患者发病时心肌酶水平与脑梗死严重程度的关系。方法将60例高龄老年脑梗死患者作为观察组,按照病情轻、中、重度分组,每组20例。同时选择60例同期到本院的体检健康的研究者作为对照组。并于入院24 h内测量血清心肌酶水平,比较心肌酶水平差异,并分析其与神经功能缺损程度的相关性。结果观察组的心肌酶水平分别和对照组比较,差异有统计学意义(P<0.05)。重度患者天冬氨酸转氨酶、乳酸脱氢酶、肌酸磷酸激酶及肌酸磷酸激酶同工酶和中度患者比较差异有统计学意义(P <0.05)。中度患者天冬氨酸转氨酶、乳酸脱氢酶、肌酸磷酸激酶及肌酸磷酸激酶同工酶和轻度患者比较差异有统计学意义(P <0.05)。观察组神经功能缺损明显高于对照组患者(P <0.05)。结论急性脑梗死发生时,血清心肌酶变化程度对病情的严重程度有一定的提示作用。
Objective To investigate the relationship between myocardial enzyme level and the severity of cerebral infarction in elderly patients with cerebral infarction. Methods Sixty elderly patients with cerebral infarction were enrolled in the study group. The patients were divided into light, moderate and severe groups, with 20 cases in each group. At the same time, 60 researchers who were in the hospital for physical examination at the same time were selected as the control group. Serum myocardial enzyme levels were measured within 24 hours of admission, and differences in myocardial enzyme levels were compared and analyzed for correlation with neurological deficits. Results The myocardial enzyme levels in the observation group were significantly different from those in the control group(P <0.05). There were significant differences between the patients with severe aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase and creatine phosphokinase isoenzyme and moderate patients(P<0.05). There were significant differences between the moderate patients with aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase and creatine phosphokinase isoenzyme and mild patients(P<0.05). The neurological deficit in the observation group was significantly higher than that in the control group(P<0.05). Conclusion When acute cerebral infarction occurs, the degree of serum myocardial enzyme changes has a certain suggestive effect on the severity of the disease.
Objective To investigate the relationship between myocardial enzyme level and the severity of cerebral infarction in elderly patients with cerebral infarction. Methods Sixty elderly patients with cerebral infarction were enrolled in the study group. The patients were divided into light, moderate and severe groups, with 20 cases in each group. At the same time, 60 researchers who were in the hospital for physical examination at the same time were selected as the control group. Serum myocardial enzyme levels were measured within 24 hours of admission, and differences in myocardial enzyme levels were compared and analyzed for correlation with neurological deficits. Results The myocardial enzyme levels in the observation group were significantly different from those in the control group(P <0.05). There were significant differences between the patients with severe aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase and creatine phosphokinase isoenzyme and moderate patients(P<0.05). There were significant differences between the moderate patients with aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase and creatine phosphokinase isoenzyme and mild patients(P<0.05). The neurological deficit in the observation group was significantly higher than that in the control group(P<0.05). Conclusion When acute cerebral infarction occurs, the degree of serum myocardial enzyme changes has a certain suggestive effect on the severity of the disease.
引文
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[9]李冰,姜艳艳,王静云,等.脑梗死患者血清心肌酶变化60例临床分析[J].中国综合临床,2013,29(9):900-902.
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[11]徐乎,郭桂香,高云春,等.常德市人群脑卒中发病类型的分布特征分析[J].中华神经医学杂志,2013,12(7):707-710.
[12]石宗华,高传玉,刘林刚.急性重症颅脑疾病患者心肌酶谱水平变化[J].中华实用诊断与治疗杂志,2013,27(9):925-926.
[2]王红燕,罗志刚,许加恒,等.盐酸艾司洛尔对伴有心肌酶异常的急性脑梗死患者血浆NT-proBNP、心型脂肪酸结合蛋白及心功能的影响[J].中国生化药物杂志,2015,35(24):138-140.
[3]胡永寸.冠心病患者血清生长分化因子-15和脑钠肽及超敏C反应蛋白水平的变化[J].中华老年医学杂志,2015,34(9):962-963.
[4]严虹,洪素华.心肌肌钙蛋白Ⅰ、肌酸激酶同工酶及高敏C反应蛋白检测与儿童病毒性心肌炎诊断的临床研究[J].中国卫生标准管理,2015,6(12):28-30.
[5]徐晓琳,吴岑,冯娟.急性脑梗死患者90d预后的相关因素分析[J].卒中与神经疾病,2015,22(9):21-24.
[6]陈荣平,高宏章,林鸣.老年脑梗死患者心肌酶水平与脑梗死严重程度临床意义探讨[J].中国实用医药,2015,10(9):83-84.
[7]金士萍.临床急诊检验心肌酶谱检测的意义分析[J].中国实用医药,2015,10(17):112-113.
[8]杨蕊.老年脑梗死患者心肌酶水平与脑梗死严重程度的相关性探讨[J].中华实验外科杂志,2014,20(3):423-425.
[9]李冰,姜艳艳,王静云,等.脑梗死患者血清心肌酶变化60例临床分析[J].中国综合临床,2013,29(9):900-902.
[10]杨蕊.老年脑梗死患者心肌酶水平与脑梗死严重程度的相关性探讨[J].河北医学,2014,20(3):423-425.
[11]徐乎,郭桂香,高云春,等.常德市人群脑卒中发病类型的分布特征分析[J].中华神经医学杂志,2013,12(7):707-710.
[12]石宗华,高传玉,刘林刚.急性重症颅脑疾病患者心肌酶谱水平变化[J].中华实用诊断与治疗杂志,2013,27(9):925-926.