保湿性敷料覆盖肉芽创面自体微粒皮移植术治疗深度烧伤创面临床研究
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摘要
目的:探讨保湿性敷料覆盖肉芽创面自体微粒皮移植术治疗深度烧伤创面的疗效。方法:80例深度烧伤患者,随机分为观察组72例,对照组8例。观察组采用保湿性敷料覆盖肉芽创面自体微粒皮移植术进行治疗,对照组采用生物敷料覆盖削痂植皮术进行治疗。比较两组患者疗效、创面愈合时间和愈合率;观察记录两组患者治疗情况及并发症发生情况。结果:观察组治疗总有效率为97.22%,对照组治疗总有效率为75.00%(P<0.05);观察组创面愈合时间明显低于对照组(P<0.05);10d创面愈合率显著高于对照组(P<0.05);观察组上皮组织完全覆盖创面时间、住院时间及疼痛评分均明显低于对照组(P<0.05);观察并发症发生率显著低于对照组(P<0.05)。结论:深度烧伤患者应用保湿性敷料覆盖肉芽创面自体微粒皮移植术效果显著,并发症少,值得临床推广应用。
Objective:To study Analysis of the clinical application of the skin grafting for deep burn wound with moisturizing dressing.Methods:80 cases of deep burn patients admitted to our hospital from May 2013 to June2015 were selected as the research objects.There were 72 cases in the observation group and 8 in the control group.The observation group was treated with a moisturizing dressing covering the skin grafting of granuloma,and the control group was treated with a biologic dressing to cover the skin grafting.The efficacy,wound healing time and healing rate of the two groups were compared.The treatment and complications of the two groups were observed.Results:The total effective rate of the observation group was 97.22%,and that of the control group was 75.00%(P<0.05).The wound healing time of the observation group was significantly lower than that of the control group(P<0.05).The wound healing rate on day 10 was significantly higher than that of the control group(P<0.05).The time of complete epithelium coverage wound,length of hospitalization and pain score of the observation group were significantly lower than those of the control group(P<0.05).The observed complication rate was significantly lower than the control group(P<0.05).Conclusion:Applying moisturizing dressing to cover granulation wound with autologous microne skin grafting in deep burn patients has remarkable effect and few complications,which is worthy of clinical application.
Objective:To study Analysis of the clinical application of the skin grafting for deep burn wound with moisturizing dressing.Methods:80 cases of deep burn patients admitted to our hospital from May 2013 to June2015 were selected as the research objects.There were 72 cases in the observation group and 8 in the control group.The observation group was treated with a moisturizing dressing covering the skin grafting of granuloma,and the control group was treated with a biologic dressing to cover the skin grafting.The efficacy,wound healing time and healing rate of the two groups were compared.The treatment and complications of the two groups were observed.Results:The total effective rate of the observation group was 97.22%,and that of the control group was 75.00%(P<0.05).The wound healing time of the observation group was significantly lower than that of the control group(P<0.05).The wound healing rate on day 10 was significantly higher than that of the control group(P<0.05).The time of complete epithelium coverage wound,length of hospitalization and pain score of the observation group were significantly lower than those of the control group(P<0.05).The observed complication rate was significantly lower than the control group(P<0.05).Conclusion:Applying moisturizing dressing to cover granulation wound with autologous microne skin grafting in deep burn patients has remarkable effect and few complications,which is worthy of clinical application.
引文
[1]肖厚安,任军勃,王梅,等.自体微粒皮在深度烧伤患者肉芽创面移植的效果观察[J].陕西医学杂志,2014,43(10):1300-1301.
[2]宁勇,刘明锁,刘文文,等.异种脱细胞真皮基质覆盖自体微粒皮治疗大面积深度烧伤疗效观察[J].山东医药,2014,54(44):91-92.
[3] Bijli AH,Bashir SA,Rasool A,et al.Contralateral lumbo-umbilical flap:A versatile technique for volar finger coverage[J].Indian J Plast Surg,2017,50(2):201-206.
[4]张宜澜,彭代智,段小冬,等.自体微粒皮移植术修复深度烧伤创面的临床分析[J].第三军医大学学报,2015,37(9):916-920.
[5]肖厚安,王梅,周小茜,等.自体微粒皮移植治疗慢性难愈性创面98例[J].陕西医学杂志,2015,44(10):1323-1350.
[6]张宜澜,彭代智.微粒皮移植术修复深度烧伤创面的研究进展[J].中华损伤与修复杂志:电子版,2016,11(4):310-313.
[7]占卫兵.改良式异体皮加自体微粒皮移植治疗大面积烧伤的研究[J].中华全科医学,2015,13(4):581-583.
[8] Karki B,Rai SM,Nakarmi KK,et al.Clinical Epidemiology of Acute Burn Injuries at Nepal Cleft and Burn Centre,Kathmandu,Nepal[J].Ann Plast Surg,2018,80(3Suppl 2):S95-S97.
[9]倪少俊,王成,杨军,等.改良式异体皮加自体微粒皮移植治疗大面积烧伤效果观察[J].河南医学研究,2016,25(11):1957-1958.
[10] Kinikoglu B.A comparison of scaffold-free and scaffoldbased reconstructed human skin models as alternatives to animal use[J].Altern Lab Anim,2017,45(6):309-316.
[11]樊红朝.大面积深度烧伤患者自体微粒皮移植异体皮覆盖的手术护理体会[J].世界最新医学信息文摘,2016,16(A0):308-309.
[12]郑小鹏,肖仕初.微粒皮移植现状及展望[J].中华损伤与修复杂志:电子版,2016,11(6):462-464.
[13]宋国栋,石文,高聪,等.大面积深度烧伤的早期切除与皮肤移植[J].中华损伤与修复杂志:电子版,2017,12(1):56-60.
[14]王文雪.微粒皮移植术修复深度烧伤创面进展研究[J].临床医药文献电子杂志,2017,4(76):15047-15048.
[2]宁勇,刘明锁,刘文文,等.异种脱细胞真皮基质覆盖自体微粒皮治疗大面积深度烧伤疗效观察[J].山东医药,2014,54(44):91-92.
[3] Bijli AH,Bashir SA,Rasool A,et al.Contralateral lumbo-umbilical flap:A versatile technique for volar finger coverage[J].Indian J Plast Surg,2017,50(2):201-206.
[4]张宜澜,彭代智,段小冬,等.自体微粒皮移植术修复深度烧伤创面的临床分析[J].第三军医大学学报,2015,37(9):916-920.
[5]肖厚安,王梅,周小茜,等.自体微粒皮移植治疗慢性难愈性创面98例[J].陕西医学杂志,2015,44(10):1323-1350.
[6]张宜澜,彭代智.微粒皮移植术修复深度烧伤创面的研究进展[J].中华损伤与修复杂志:电子版,2016,11(4):310-313.
[7]占卫兵.改良式异体皮加自体微粒皮移植治疗大面积烧伤的研究[J].中华全科医学,2015,13(4):581-583.
[8] Karki B,Rai SM,Nakarmi KK,et al.Clinical Epidemiology of Acute Burn Injuries at Nepal Cleft and Burn Centre,Kathmandu,Nepal[J].Ann Plast Surg,2018,80(3Suppl 2):S95-S97.
[9]倪少俊,王成,杨军,等.改良式异体皮加自体微粒皮移植治疗大面积烧伤效果观察[J].河南医学研究,2016,25(11):1957-1958.
[10] Kinikoglu B.A comparison of scaffold-free and scaffoldbased reconstructed human skin models as alternatives to animal use[J].Altern Lab Anim,2017,45(6):309-316.
[11]樊红朝.大面积深度烧伤患者自体微粒皮移植异体皮覆盖的手术护理体会[J].世界最新医学信息文摘,2016,16(A0):308-309.
[12]郑小鹏,肖仕初.微粒皮移植现状及展望[J].中华损伤与修复杂志:电子版,2016,11(6):462-464.
[13]宋国栋,石文,高聪,等.大面积深度烧伤的早期切除与皮肤移植[J].中华损伤与修复杂志:电子版,2017,12(1):56-60.
[14]王文雪.微粒皮移植术修复深度烧伤创面进展研究[J].临床医药文献电子杂志,2017,4(76):15047-15048.