摘要
<正>肺诺卡菌病是由诺卡菌引起的侵袭肺部的化脓性或肉芽肿性疾病。该病临床比较少见,随着免疫抑制剂及糖皮质激素的使用,造血干细胞移植、恶性肿瘤、糖尿病及HIV感染患者的增多,近年来发病率有上升趋势。肺诺卡菌病临床表现无特异性,易误诊,若诊治不及时,病死率比较高[1-2]。该病诊断的关键
引文
[1]MARTNEZ TOMS R,MENNDEZ VILLANUEVA R,REYES CALZADA S,et al.Pulmonary nocardiosis:risk factors and outcomes[J].Respirology,2007,12(3):394-400.
[2]HARTFORD O A,POTHIAWALA G A,GOLDMAN G D.Ulcerated facial nodules in a renal transplant recipient--quiz case.diagnosis:primary cutaneous nocardiosis.[J].Arch Dermatol,2010,146(1):81-86.
[3]BROWN-ELLIOTT B,BROWN J M,CONVILLE P S,et al.Clinical and laboratory features of the nocardia spp.based on current molecular taxonomy.[J].Clin Microbiol Rev,2006,19(2):259-282.
[4]KANNE J P,YANDOW D R,MOHAMMED T L,et al.CT findings of pulmonary nocardiosis[J].AJR Am J Roentgenol,2011,197(2):W266-W272.
[5]CHEN J J,ZHOU H,XU P F,et al.Clinical and radiographic characteristics of pulmonary nocardiosis:clues to earlier diagnosis[J].PLoS One,2014,9(3):e90724.
[6]SALIPANTE S J,SENGUPTA D J,HOOGESTRAAT D R,et al.Molecular diagnosis of Actinomadura madurae infectionby 16SrRNA deep sequencing[J].J Clin Microbio,2013,51(12):4262-4265.
[7]WILSON J W.Nocardiosis:updates and clinical overview[J].Mayo Clin Proc,2012,87(4):403-407.
[8]AGTEROF M J,VAN DER BRUGGEN T,TERSMETTE M,et al.Nocardiosis:a case series and a mini review of clinical and microbiological features[J].Neth J Med,2007,65(6):199-202.