多囊卵巢综合征患者睾酮水平与卵巢超声检测指标的关系分析
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摘要
目的:分析多囊卵巢综合征患者睾酮水平与卵巢超声检测指标的关系。方法:选取2017年1月—2018年10月本院收治的多囊卵巢综合征患者68例为观察组,同时期健康同龄妇女68例为对照组。比较两组血睾酮水平及卵巢超声检测指标(卵巢间质及总面积、卵巢体积、卵泡数、卵巢间质动脉及子宫动脉PI及RI),比较观察组中不同睾酮水平者的上述卵巢超声检测指标,分析患者睾酮水平与卵巢超声检测指标相关性。结果:观察组血睾酮水平、卵巢间质及总面积、卵巢体积、卵泡数、子宫动脉PI及RI均高于对照组,卵巢间质动脉PI及RI均低于对照组,差异均有统计学意义(P<0.05);观察组中不同睾酮水平者的卵巢超声检测各指标比较,差异均有统计学意义(P<0.05);Pearson相关性分析显示,多囊卵巢综合征患者睾酮水平与卵巢间质及总面积、卵巢体积、卵泡数、子宫动脉PI及RI均呈正相关(P<0.05),与卵巢间质动脉PI及RI均呈负相关(P<0.05)。结论:多囊卵巢综合征患者睾酮水平与卵巢超声检测指标均呈现异常的状态,且睾酮水平与卵巢超声检测指标有密切的关系,应重视对多囊卵巢综合征患者睾酮水平与卵巢超声检测指标的监测与调控。
Objective:To analyze the relationship between testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome.Method:A total of 68 patients with polycystic ovary syndrome from January 2017 to October 2018 were selected as observation group,68 healthy women of the same ages at the same time were selected as control group.The blood testosterone level and ovarian ultrasound detection indexes(ovarian stroma and total area,ovarian volume,follicle number,ovarian interstitial artery and uterine artery PI and RI)of two groups were compared,and those ovarian ultrasound detection indexes of observation group with different testosterone levels were compared,the relationship between testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome were analyzed.Result:The blood testosterone level,ovarian stroma and total area,ovarian volume,follicle number,ovarian interstitial artery PI and RI of observation group were higher than those of control group,the uterine artery PI and RI were lower than those of control group,the differences were statistically significant(P<0.05).The ovarian ultrasound detection indexes of observation group with different testosterone levels were compared,the differences were statistically significant(P<0.05).The Pearson correlation analysis showed testosterone level of patients with polycystic ovary syndrome were positively correlated with ovarian stroma and total area,ovarian volume,follicle number,ovarian interstitial artery PI and RI(P<0.05),and it was negatively correlated with uterine artery PI and RI(P<0.05).Conclusion:The testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome all show abnormal state,and the testosterone level have close relationship to the ovarian ultrasound detection indexes,so the testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome should be paid to more attention.
Objective:To analyze the relationship between testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome.Method:A total of 68 patients with polycystic ovary syndrome from January 2017 to October 2018 were selected as observation group,68 healthy women of the same ages at the same time were selected as control group.The blood testosterone level and ovarian ultrasound detection indexes(ovarian stroma and total area,ovarian volume,follicle number,ovarian interstitial artery and uterine artery PI and RI)of two groups were compared,and those ovarian ultrasound detection indexes of observation group with different testosterone levels were compared,the relationship between testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome were analyzed.Result:The blood testosterone level,ovarian stroma and total area,ovarian volume,follicle number,ovarian interstitial artery PI and RI of observation group were higher than those of control group,the uterine artery PI and RI were lower than those of control group,the differences were statistically significant(P<0.05).The ovarian ultrasound detection indexes of observation group with different testosterone levels were compared,the differences were statistically significant(P<0.05).The Pearson correlation analysis showed testosterone level of patients with polycystic ovary syndrome were positively correlated with ovarian stroma and total area,ovarian volume,follicle number,ovarian interstitial artery PI and RI(P<0.05),and it was negatively correlated with uterine artery PI and RI(P<0.05).Conclusion:The testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome all show abnormal state,and the testosterone level have close relationship to the ovarian ultrasound detection indexes,so the testosterone level and ovarian ultrasound detection indexes of patients with polycystic ovary syndrome should be paid to more attention.
引文
[1]王静,王爽.多囊卵巢综合征超声表现与临床病理特点相关性[J].医学研究杂志,2018,47(4):164-166,174.
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[3]梁美艳,王莉.肥胖型与非肥胖型多囊卵巢综合征超声指标与内分泌指标的关系分析[J].临床超声医学杂志,2018,20(3):195-197.
[4]李佩芝.育龄期多囊卵巢综合征患者卵巢超声影像学特征及诊断分析[J].影像研究与医学应用,2017,1(7):81-82.
[5]寇燕妮,马晓梅,冯春香.多囊卵巢综合征不同临床表现患者超声参数与内分泌指标特征分析[J].临床医学工程,2017,24(11):1501-1502.
[6]陶云,张芳,王政强.肥胖型与非肥胖型多囊卵巢综合征患者超声参数与内分泌指标特征比较[J].中国妇幼保健,2017,32(16):3774-3776.
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[8]张杰,张翔,延静,等.多囊卵巢综合征超声影像特征及与性激素、胰岛素抵抗指数的相关性分析[J].医学临床研究,2017,34(3):456-458.
[9]Song D K,Oh J Y,Lee H,et al.Differentiation between polycystic ovary syndrome and polycystic ovarian morphology by means of an anti-Müllerian hormone cutoff value[J].Korean J Intern Med,2016,32(4):690-698.
[10]孙寒冰,刘艳,林澍,等.多囊卵巢综合征的超声形态学特征及量化分析[J].医学综述,2016,22(22):4510-4512,4518.
[11]Sujata K,Swoyam S.2D and 3D Trans-vaginal Sonography to Determine Cut-offs for Ovarian Volume and Follicle Number per Ovary for Diagnosis of Polycystic Ovary Syndrome in Indian Women[J].J Reprod Infertil,2018,19(3):146-151.
[12]马广志.多囊卵巢综合征卵巢超声影像学特征及其与内分泌代谢异常的相关性分析[J/OL].中西医结合心血管病电子杂志,2017,5(2):54-55.
[13]阮郑,寿炎明,田国琴,等.不同表现多囊卵巢综合征患者超声参数与内分泌指标的相关性研究[J].中国性科学,2016,25(5):63-65.
[14]王金玲.多囊卵巢综合征患者彩色多普勒超声血流变化及其与内分泌参数的相关性[J].实用临床医药杂志,2016,20(17):81-84.
[15]郑国华,王爱婷,李文欣,等.多囊卵巢综合征不孕症患者血清睾酮水平变化及与机体氧化应激的关系[J].山东医药,2015,55(11):55-56.
[16]张适恩,侯艺园,赖大行.多囊卵巢综合征的性激素、胰岛素抵抗与超声影像相关性分析[J].国际检验医学杂志,2015,36(14):2036-2037.
[17]陆新虹,杨海燕,罗佐杰,等.不同胰岛素抵抗状态下多囊卵巢综合征患者内分泌指标与卵巢超声特征的相关性研究[J].中国糖尿病杂志,2015,23(1):40-42.
[18]田琪.多囊卵巢综合征彩色多普勒超声诊断的特征及价值[J].深圳中西医结合杂志,2018,28(9):89-90.
[19]张雅冬,许昕.不同证型多囊卵巢综合征与超声下卵巢参数的相关性研究[J].环球中医药,2018,11(7):1018-1021.
[20]薛晓蕊,范春艳.多囊卵巢综合征的超声检查研究进展[J].医学综述,2016,22(19):3863-3867.
[2]姜咏华,丁延华.多囊卵巢综合征患者三维能量多普勒超声参数及血清性激素水平分析[J].中国卫生检验杂志,2018,28(13):1583-1585.
[3]梁美艳,王莉.肥胖型与非肥胖型多囊卵巢综合征超声指标与内分泌指标的关系分析[J].临床超声医学杂志,2018,20(3):195-197.
[4]李佩芝.育龄期多囊卵巢综合征患者卵巢超声影像学特征及诊断分析[J].影像研究与医学应用,2017,1(7):81-82.
[5]寇燕妮,马晓梅,冯春香.多囊卵巢综合征不同临床表现患者超声参数与内分泌指标特征分析[J].临床医学工程,2017,24(11):1501-1502.
[6]陶云,张芳,王政强.肥胖型与非肥胖型多囊卵巢综合征患者超声参数与内分泌指标特征比较[J].中国妇幼保健,2017,32(16):3774-3776.
[7]Dumesic D A,Oberfield S E,Stener-Victorin E,et al.Scientific Statement on the Diagnostic Criteria,Epidemiology,Pathophysiology,and Molecular Genetics of Polycystic Ovary Syndrome[J].Endocr Rev,2015,36(5):487-525.
[8]张杰,张翔,延静,等.多囊卵巢综合征超声影像特征及与性激素、胰岛素抵抗指数的相关性分析[J].医学临床研究,2017,34(3):456-458.
[9]Song D K,Oh J Y,Lee H,et al.Differentiation between polycystic ovary syndrome and polycystic ovarian morphology by means of an anti-Müllerian hormone cutoff value[J].Korean J Intern Med,2016,32(4):690-698.
[10]孙寒冰,刘艳,林澍,等.多囊卵巢综合征的超声形态学特征及量化分析[J].医学综述,2016,22(22):4510-4512,4518.
[11]Sujata K,Swoyam S.2D and 3D Trans-vaginal Sonography to Determine Cut-offs for Ovarian Volume and Follicle Number per Ovary for Diagnosis of Polycystic Ovary Syndrome in Indian Women[J].J Reprod Infertil,2018,19(3):146-151.
[12]马广志.多囊卵巢综合征卵巢超声影像学特征及其与内分泌代谢异常的相关性分析[J/OL].中西医结合心血管病电子杂志,2017,5(2):54-55.
[13]阮郑,寿炎明,田国琴,等.不同表现多囊卵巢综合征患者超声参数与内分泌指标的相关性研究[J].中国性科学,2016,25(5):63-65.
[14]王金玲.多囊卵巢综合征患者彩色多普勒超声血流变化及其与内分泌参数的相关性[J].实用临床医药杂志,2016,20(17):81-84.
[15]郑国华,王爱婷,李文欣,等.多囊卵巢综合征不孕症患者血清睾酮水平变化及与机体氧化应激的关系[J].山东医药,2015,55(11):55-56.
[16]张适恩,侯艺园,赖大行.多囊卵巢综合征的性激素、胰岛素抵抗与超声影像相关性分析[J].国际检验医学杂志,2015,36(14):2036-2037.
[17]陆新虹,杨海燕,罗佐杰,等.不同胰岛素抵抗状态下多囊卵巢综合征患者内分泌指标与卵巢超声特征的相关性研究[J].中国糖尿病杂志,2015,23(1):40-42.
[18]田琪.多囊卵巢综合征彩色多普勒超声诊断的特征及价值[J].深圳中西医结合杂志,2018,28(9):89-90.
[19]张雅冬,许昕.不同证型多囊卵巢综合征与超声下卵巢参数的相关性研究[J].环球中医药,2018,11(7):1018-1021.
[20]薛晓蕊,范春艳.多囊卵巢综合征的超声检查研究进展[J].医学综述,2016,22(19):3863-3867.