缬沙坦联合黄葵胶囊治疗高血压合并糖尿病肾病的效果
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摘要
目的:分析缬沙坦联合黄葵胶囊治疗高血压合并糖尿病肾病的效果。方法:以笔者所在医院2016年4月-2017年9月住院治疗的77例高血压合并2型糖尿病肾病患者为观察对象,以随机数字表法将其分为对照组(38例)、研究组(39例),对照组仅服用缬沙坦治疗,研究组在对照组治疗基础上联合服用黄葵胶囊,分析两组治疗情况、不良反应。结果:治疗后,研究组DBP、SBP、24 h尿蛋白定量明显低于对照组,差异均有统计学意义(P<0.05);研究组UAEF低于对照组,差异有统计学意义(P<0.05);研究组CRP、TC、TG水平低于对照组,差异均有统计学意义(P<0.05)。结论:对高血压合并2型糖尿病肾病患者提供缬沙坦联合黄葵胶囊治疗,有助于控制患者血压,维持血糖理想水平,保护肾脏功能。
Objective:To analyze the effect of Valsartan combined with Ambrette Capsule on the treatment of hypertension with diabetic nephropathy.Method:From April 2016 to September 2017,77 patients hospitalized in our hospital with high blood pressure and type 2 diabetic nephropathy were selected as observation object.By the method of random numbers table they were divided into control group(38 cases) and study group(39 cases).The control group was takenValsartan treatment,on this basis,the study group combined Ambrette Capsule.The two groups of treatment effect and adverse reactions were analyzed.Result:After treatment,the DBP,SBP and 24 h urinary protein of the study group were significantly lower than those of the control group,and the differences were statistically significant(P<0.05).UAEF level of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).The levels of CRP,TC and TG in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion:The treatment of Valsartan combined with Huangkui Capsule in patients with hypertension and type 2 diabetic nephropathy can help control blood pressure,maintain ideal blood sugar level and protect kidney function.
Objective:To analyze the effect of Valsartan combined with Ambrette Capsule on the treatment of hypertension with diabetic nephropathy.Method:From April 2016 to September 2017,77 patients hospitalized in our hospital with high blood pressure and type 2 diabetic nephropathy were selected as observation object.By the method of random numbers table they were divided into control group(38 cases) and study group(39 cases).The control group was takenValsartan treatment,on this basis,the study group combined Ambrette Capsule.The two groups of treatment effect and adverse reactions were analyzed.Result:After treatment,the DBP,SBP and 24 h urinary protein of the study group were significantly lower than those of the control group,and the differences were statistically significant(P<0.05).UAEF level of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).The levels of CRP,TC and TG in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion:The treatment of Valsartan combined with Huangkui Capsule in patients with hypertension and type 2 diabetic nephropathy can help control blood pressure,maintain ideal blood sugar level and protect kidney function.
引文
[1]马亚丽,陈芳,时军,等.缬沙坦联合前列地尔对早期糖尿病肾病的临床研究[J].中国临床药理学杂志,2016,32(5):409-411.
[2]高华荣,孙相民,陈英,等.缬沙坦联合黄葵胶囊对高血压合并Ⅱ型糖尿病肾病患者血压血糖水平和肾脏的影响[J].西部医学,2017,29(11):1582-1586.
[3]温丽平.氨氯地平联合缬沙坦治疗老年原发性高血压合并糖尿病的疗效观察[J].中西医结合心脑血管病杂志,2016,14(10):1146-1148.
[4]林彩云,陈武,何淑芬.硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的效果[J].山东医药,2017,57(5):84-86.
[5]肖芝梅,丁晨慧,骆臣.黄葵胶囊治疗慢性肾炎的临床疗效及对血脂代谢、肾功能影响分析[J].临床和实验医学杂志,2017,16(22):2241-2243.
[6]高刺丽.缬沙坦联合吲达帕胺治疗对高血压合并糖尿病患者肾功能的影响研究[J].山西医药杂志,2016,45(2):159-161.
[7]张新丽,靳锋,丁文君,等.补肾活血方联合缬沙坦胶囊治疗糖尿病肾病Ⅲ期30例[J].西部中医药,2017,30(10):99-102.
[8]戴璇,袁连方,李月红.黄葵胶囊联合缬沙坦治疗早期糖尿病肾病的临床疗效及安全性观察[J].天津中医药,2017,34(3):163-164.
[9]陈松,顾波,王汉清,等.硝苯地平控释片联合缬沙坦治疗对2型糖尿病肾病合并高血压患者血清学指标的影响[J].海南医学院学报,2016,22(13):1398-1401.
[10]王彦,唐琳.舒洛地特注射液联合缬沙坦胶囊治疗糖尿病肾病的临床研究[J].中国临床药理学杂志,2016,32(21):1953-1956.
[11]陈玉华.硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的疗效观察[J].糖尿病新世界,2017,20(3):172-173.
[12]朱俊利.黄葵胶囊联合缬沙坦治疗糖尿病肾病对肾功能及炎症因子的影响[J].现代中西医结合杂志,2017,26(17):1925-1926.
[2]高华荣,孙相民,陈英,等.缬沙坦联合黄葵胶囊对高血压合并Ⅱ型糖尿病肾病患者血压血糖水平和肾脏的影响[J].西部医学,2017,29(11):1582-1586.
[3]温丽平.氨氯地平联合缬沙坦治疗老年原发性高血压合并糖尿病的疗效观察[J].中西医结合心脑血管病杂志,2016,14(10):1146-1148.
[4]林彩云,陈武,何淑芬.硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的效果[J].山东医药,2017,57(5):84-86.
[5]肖芝梅,丁晨慧,骆臣.黄葵胶囊治疗慢性肾炎的临床疗效及对血脂代谢、肾功能影响分析[J].临床和实验医学杂志,2017,16(22):2241-2243.
[6]高刺丽.缬沙坦联合吲达帕胺治疗对高血压合并糖尿病患者肾功能的影响研究[J].山西医药杂志,2016,45(2):159-161.
[7]张新丽,靳锋,丁文君,等.补肾活血方联合缬沙坦胶囊治疗糖尿病肾病Ⅲ期30例[J].西部中医药,2017,30(10):99-102.
[8]戴璇,袁连方,李月红.黄葵胶囊联合缬沙坦治疗早期糖尿病肾病的临床疗效及安全性观察[J].天津中医药,2017,34(3):163-164.
[9]陈松,顾波,王汉清,等.硝苯地平控释片联合缬沙坦治疗对2型糖尿病肾病合并高血压患者血清学指标的影响[J].海南医学院学报,2016,22(13):1398-1401.
[10]王彦,唐琳.舒洛地特注射液联合缬沙坦胶囊治疗糖尿病肾病的临床研究[J].中国临床药理学杂志,2016,32(21):1953-1956.
[11]陈玉华.硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的疗效观察[J].糖尿病新世界,2017,20(3):172-173.
[12]朱俊利.黄葵胶囊联合缬沙坦治疗糖尿病肾病对肾功能及炎症因子的影响[J].现代中西医结合杂志,2017,26(17):1925-1926.