胎儿甲状腺发育异常与母体高危因素Logistic回归分析
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摘要
目的探讨胎儿甲状腺发育异常与母体高危因素的相关性。方法选取胎儿甲状腺发育异常58例为实验组,健康者90例为对照组,分析两组高危因素,并进行Logistic回归分析。结果两组结果显示实验组中母体既往有甲状腺功能异常及甲状腺手术病史、甲状腺肿、甲状腺自身抗体阳性、头颈部放射史、流产和早产病史高危因素者所占比例显著高于对照组(P<0.05)。Logistic分析示,上述高危因素是胎儿甲状腺发育异常的主要因素。结论母体既往有甲状腺功能异常及甲状腺手术病史、甲状腺肿、甲状腺自身抗体阳性、头颈部放射史、流产和早产病史是引起胎儿甲状腺发育异常的主要因素。
Objective To explore the correlation between fetal thyroid dysplasia and maternal risk factors.Methods Select abnormal fetal thyroid ultrasound images as the experimental group(n=58),normal fetal thyroid ultrasound images as control group(n=90).Analysis of high risk factors in both groups and logistic regression analysis.Results The results of the two groups showed that the proportion of maternal thyroid dysfunction and thyroid surgery history,goiter,thyroid autoantibodies,head and neck radiation history,abortion and premature birth risk factors were significantly higher in the experimental group than in the observation group.(P<0.05)Logistic analysis showed that the above-mentioned high risk factors are the main factors of fetal thyroid dysplasia.Conclusions The above five factors are the main factors causing fetal thyroid dysplasia.
Objective To explore the correlation between fetal thyroid dysplasia and maternal risk factors.Methods Select abnormal fetal thyroid ultrasound images as the experimental group(n=58),normal fetal thyroid ultrasound images as control group(n=90).Analysis of high risk factors in both groups and logistic regression analysis.Results The results of the two groups showed that the proportion of maternal thyroid dysfunction and thyroid surgery history,goiter,thyroid autoantibodies,head and neck radiation history,abortion and premature birth risk factors were significantly higher in the experimental group than in the observation group.(P<0.05)Logistic analysis showed that the above-mentioned high risk factors are the main factors of fetal thyroid dysplasia.Conclusions The above five factors are the main factors causing fetal thyroid dysplasia.
引文
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[3]单忠艳.妊娠合并甲状腺功能减退症的进展和争论[J].内科理论与实践,2010,5(2):125-129.
[4]ALAMDARI S,AZIZI F,DELSHAD H,et al.Management of Hyperthyroidism in Pregnancy:Comparison of Recommendations of American Thyroid Association and Endocrine Society[J].Journal of Thyroid Research,2013,(2013-5-22),2013,1-6.
[5]张春艳.成都地区妊娠妇女甲状腺激素正常参考值范围的建立及甲状腺疾病的筛查[D].川北医学院,2014.
[6]高金瑜.自身免疫性抗体谱与复发性流产关系的研究[D].山东大学,2006.
[2]李丽雅,吕国荣,李敏,等.产前超声建立胎儿甲状腺正常参考值[J].中国医学影像技术,2014,30(6):897-900.
[3]单忠艳.妊娠合并甲状腺功能减退症的进展和争论[J].内科理论与实践,2010,5(2):125-129.
[4]ALAMDARI S,AZIZI F,DELSHAD H,et al.Management of Hyperthyroidism in Pregnancy:Comparison of Recommendations of American Thyroid Association and Endocrine Society[J].Journal of Thyroid Research,2013,(2013-5-22),2013,1-6.
[5]张春艳.成都地区妊娠妇女甲状腺激素正常参考值范围的建立及甲状腺疾病的筛查[D].川北医学院,2014.
[6]高金瑜.自身免疫性抗体谱与复发性流产关系的研究[D].山东大学,2006.