帕金森病患者情绪与情绪词注意偏向相关分析
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摘要
目的探讨慢性帕金森病(Parkinson's Disease,PD)患者情绪与注意偏向相关性。方法将80例PD患者及80例健康对照者(health controls,HC)作为研究对象;所有被试的情绪状况水平采用焦虑症状自评量表(Self-Rating Anxiety Scale,SAS)和抑郁症状自评量表(Self-rating depression scale,SDS)进行评估;注意偏向评估采用中文情绪词stroop测试进行评估。结果 PD组在SDS得分方面高于HC组,差异有统计学意义[(50.60±10.30)分vs(44.11±12.14)分,t=-3.645,P<0.001];PD组在负性词的反应时高于HC组,差异有统计学意义[分别为(1698.71±199.86)ms,(1625.95±241.64)ms;t=-2.076,P=0.040];PD患者对负性词反应时与SDS量表得分呈正相关(r=0.241,P=0.031)。结论 PD患者存在情绪和对注意偏向方面的异常,抑郁情况与对负性词的注意偏向密切相关。
Objective To explore the correlations between the emotions and attentional bias to emotional words in patients with Parkinson's Disease. Methods A total of 80 PD patients were compared with matched 80 health controls(HC). Emotions of all the subjects were assessed by Self-Rating Anxiety Scale(SAS)、Self-Rating Depression Scale(SDS);that assessed the Attentional bias of all the subjects were assessed by Chinese Emotional Stroop Task. Results The score of SDS in PD group were higher than the HC group[(50.60±10.30)score vs(44.11±12.14)score,t=-3.645,P<0.001]. The comparison between PD group and HC group on the reaction time of negative-related words were significant[(1698.71±199.86)ms,(1625.95±241.64)ms respectively;t=-2.076,P=0.040];Response time to negative words were positively correlated with SDS score in PD patients(r=0.241,P=0.031). Conclusion The studies suggest prevalence of emotions and attentional bias problems in PD patients,Depression is closely related to attention to negative-related words.
Objective To explore the correlations between the emotions and attentional bias to emotional words in patients with Parkinson's Disease. Methods A total of 80 PD patients were compared with matched 80 health controls(HC). Emotions of all the subjects were assessed by Self-Rating Anxiety Scale(SAS)、Self-Rating Depression Scale(SDS);that assessed the Attentional bias of all the subjects were assessed by Chinese Emotional Stroop Task. Results The score of SDS in PD group were higher than the HC group[(50.60±10.30)score vs(44.11±12.14)score,t=-3.645,P<0.001]. The comparison between PD group and HC group on the reaction time of negative-related words were significant[(1698.71±199.86)ms,(1625.95±241.64)ms respectively;t=-2.076,P=0.040];Response time to negative words were positively correlated with SDS score in PD patients(r=0.241,P=0.031). Conclusion The studies suggest prevalence of emotions and attentional bias problems in PD patients,Depression is closely related to attention to negative-related words.
引文
1.中华医学会神经病学分会神经心理学与行为神经病学组.帕金森病抑郁、焦虑及精神病性障碍的诊断标准及治疗指南.中华神经科杂志,2013,46(1):56-60.
2.Kret ME,Stekelenburg JJ,de Gelder B,et al.From face to hand:attentional bias towards expressive hands in social anxiety[J].Biol Psychol.2017,122:42-50.a.Tomlinson CL,Stowe R,Patel S,et al.Systematic review of levodopa dose equivalency reporting in Parkinson′s disease[J].Movement Disorders,2010,25(15):2649-2653.
3.张作记.行为医学量表手册[M/CD].北京:中华医学电子音像出版社,2005:213-214,223-224.
4.刘凯,杨千芋,黄德馨,等.自愿戒毒者的心里韧性及其对情绪stroop效应的影响[J].中国健康心理学杂志,2016,24(10):1464-1468.
5.宋月平,代京涛,王杏微.134例帕金森病患者抑郁状况及生活质量的调查研究[J].四川医学,2013,34(6):852-853.
6.李桂花,张震中,李沛珊,等.新疆维吾尔族和汉族帕金森病患者心理健康状态分析[J].新疆医科大学学报,2015,38(11):1399-1402.
7.冯文雅,石雅琪,李俊发,等.帕金森病患者的注意功能缺陷[J].重庆医学,2012,41(6):1648-1652.
8.Lin CY,Tien YM,Huang JT,et al.Degraded Impairment of Emotion Recognition in Parkinson's Disease Extends from Negative to Positive Emotions[J].Behav Neurol.2016,2016:9287092.
9.Yuvaraj R,Murugappan M,Ibrahim NM,et al.Interhemispheric EEG coherence analysis in Parkinson's disease:assessing brain activity during emotion processing[J].J Neural Transm(Vienna).2015,122(2):237-252.
10.曲小丽,余刚.帕金森病轻度认知功能障碍研究进展[J].中国全科医学,2016,19(12):1371-1374.
11.Pierri M,Vaudano E,Sager T,et al.KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse[J].Neuropharmacology,2005,48(4):517-524.
12.Chen C,Huang J,Shang H.Influence of Self Motivation on Mental Health of Elderly People[J].MED ONE,2016,1:e160021.
2.Kret ME,Stekelenburg JJ,de Gelder B,et al.From face to hand:attentional bias towards expressive hands in social anxiety[J].Biol Psychol.2017,122:42-50.a.Tomlinson CL,Stowe R,Patel S,et al.Systematic review of levodopa dose equivalency reporting in Parkinson′s disease[J].Movement Disorders,2010,25(15):2649-2653.
3.张作记.行为医学量表手册[M/CD].北京:中华医学电子音像出版社,2005:213-214,223-224.
4.刘凯,杨千芋,黄德馨,等.自愿戒毒者的心里韧性及其对情绪stroop效应的影响[J].中国健康心理学杂志,2016,24(10):1464-1468.
5.宋月平,代京涛,王杏微.134例帕金森病患者抑郁状况及生活质量的调查研究[J].四川医学,2013,34(6):852-853.
6.李桂花,张震中,李沛珊,等.新疆维吾尔族和汉族帕金森病患者心理健康状态分析[J].新疆医科大学学报,2015,38(11):1399-1402.
7.冯文雅,石雅琪,李俊发,等.帕金森病患者的注意功能缺陷[J].重庆医学,2012,41(6):1648-1652.
8.Lin CY,Tien YM,Huang JT,et al.Degraded Impairment of Emotion Recognition in Parkinson's Disease Extends from Negative to Positive Emotions[J].Behav Neurol.2016,2016:9287092.
9.Yuvaraj R,Murugappan M,Ibrahim NM,et al.Interhemispheric EEG coherence analysis in Parkinson's disease:assessing brain activity during emotion processing[J].J Neural Transm(Vienna).2015,122(2):237-252.
10.曲小丽,余刚.帕金森病轻度认知功能障碍研究进展[J].中国全科医学,2016,19(12):1371-1374.
11.Pierri M,Vaudano E,Sager T,et al.KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse[J].Neuropharmacology,2005,48(4):517-524.
12.Chen C,Huang J,Shang H.Influence of Self Motivation on Mental Health of Elderly People[J].MED ONE,2016,1:e160021.