摘要
目的应用中药鹿血晶治疗乳腺浸润性导管癌化疗患者白细胞减少症,观察其临床疗效和对患者生活质量的影响。方法选择辽宁省肿瘤医院2016年1月—2017年12月,120例有明确病理诊断乳腺浸润性导管癌初治患者,将其随机分成研究组和对照组,每组60例。研究组采用TEC(T:多西他赛E:表柔比星C:环磷酰胺)方案化疗,联合鹿血晶治疗;对照组只采用TEC方案化疗,不服用鹿血晶,观察两组白细胞水平的变化、生活质量评分及不良反应。结果一个化疗周期后(用药21天),化疗前及化疗后7天两组白细胞水平差异均无统计学意义(P>0.05),但化疗后14天研究组白细胞水平与对照组比较,差异有统计学意义(P<0.05),对照组患者白细胞计数有所下降。结论中药鹿血晶可升高乳腺浸润导管癌化疗后患者白细胞计数且安全没有不良反应。
Objective Observe and analyze the clinical effect of Luxuejing on leukopenia in breast invasive ductal cancer patients undergoing chemotherapy and its effect on quality of life.Methods From January 2016 to December 2017,120 patients with invasive ductal carcinoma of breast diagnosed by pathology were randomly divided into study group and control group,60 cases in each group.The study group was treated with TEC(T:Docetaxel E:Epirubicin C:Cyclophosphamide) regimen combined with deer blood crystal therapy,while the control group was treated with TEC regimen only,without deer blood crystal.The changes of leucocyte level,quality of life score and adverse reactions were observed in the two groups.Results There was no significant difference in the leucocyte level between the two groups before and 7 days after chemotherapy(P>0.05) after one chemotherapy cycle(21 days after treatment),but the leucocyte level in the study group was significantly higher than that in the control group 14 days after chemotherapy(P<0.05).Leukocyte count decreased in the control group.Conclusion Luxuejing can increase the white blood cell count of patients with breast invasive ductal cancer after chemotherapy,and it is safe and has no adverse reactions.
引文
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