剖宫产与自然分娩对产妇产褥感染、血清WBC、CRP及PCT水平的影响
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摘要
目的探究剖宫产、自然分娩对产妇产褥感染、血清白细胞计数(WBC)、C反应蛋白(CRP)、降钙素原(PCT)表达的影响。方法选取本院2016年2月至2018年2月剖宫产与自然分娩产妇各198例为研究对象,分别设为剖宫产组和自然分娩组。观察两组产褥感染发生率,并比较两组产前1 d、产后3 d血清WBC、CRP及PCT水平。结果剖宫产组产褥感染总发生率为8.08%,高于自然分娩组的3.03%,差异具有统计学意义(P<0.05);剖宫产组切口感染发生率高于自然分娩组(P<0.05)。产后3 d,两组产妇WBC、CRP、PCT水平均高于产前1 d,但自然分娩组WBC、CRP、PCT水平均低于剖宫产组,差异具有统计学意义(P<0.05)。结论不同分娩方式对产妇产褥感染及血清WBC、CRP、PCT水平存在影响,剖宫产产妇的产褥感染发生率及WBC、CRP、PCT表达高于自然分娩产妇。
Objective To investigate the effect of cesarean section and natural delivery on maternal puerperal infection and the expression of serum white blood cell count(WBC), C-reactive protein(CRP) and procalcitonin(PCT). Methods One hundred and ninety-eight cases of cesarean section and 198 cases of natural delivery in our hospital from February2016 to February 2018 were selected as the research objects, and they were divided into cesarean section group and natural delivery group. The incidences of puerperal infection between the two groups were observed, and the levels of serum WBC,CRP and PCT in the two groups at 1 day before delivery and 3 days after delivery were compared. Results The total incidence of puerperal infection in the cesarean section group was 8.08%, which was higher than 3.03% in the natural delivery group, and the difference was statistically significant(P <0.05), and the incidence of incision infection in the cesarean section group was higher than that in the natural delivery group(P<0.05). At 3 days after delivery, the levels of WBC, CRP and PCT in the two groups were higher than those at 1 day after delivery, but the levels of WBC, CRP and PCT in the natural delivery group were lower than those in the cesarean section group, and the differences were statistically significant(P <0.05). Conclusion Puerperal infection and levels of serum WBC, CRP and PCT are affected by different delivery modes. The incidence of puerperal infection and expression of WBC, CRP and PCT in the cesarean section women are higher than those in the natural delivery women.
Objective To investigate the effect of cesarean section and natural delivery on maternal puerperal infection and the expression of serum white blood cell count(WBC), C-reactive protein(CRP) and procalcitonin(PCT). Methods One hundred and ninety-eight cases of cesarean section and 198 cases of natural delivery in our hospital from February2016 to February 2018 were selected as the research objects, and they were divided into cesarean section group and natural delivery group. The incidences of puerperal infection between the two groups were observed, and the levels of serum WBC,CRP and PCT in the two groups at 1 day before delivery and 3 days after delivery were compared. Results The total incidence of puerperal infection in the cesarean section group was 8.08%, which was higher than 3.03% in the natural delivery group, and the difference was statistically significant(P <0.05), and the incidence of incision infection in the cesarean section group was higher than that in the natural delivery group(P<0.05). At 3 days after delivery, the levels of WBC, CRP and PCT in the two groups were higher than those at 1 day after delivery, but the levels of WBC, CRP and PCT in the natural delivery group were lower than those in the cesarean section group, and the differences were statistically significant(P <0.05). Conclusion Puerperal infection and levels of serum WBC, CRP and PCT are affected by different delivery modes. The incidence of puerperal infection and expression of WBC, CRP and PCT in the cesarean section women are higher than those in the natural delivery women.
引文
[1]陈巧巧,雷明,汤飒爽,等.剖宫产产褥感染产妇的血清降钙素原与C-反应蛋白水平变化研究[J].中华医院感染学杂志,2016,26(19):4503-4505.
[2]CHEN Y,HAN X,GUO P,et al.Bacteramia caused by gardnerella vaginalis in a cesarean section patient[J].Clin Lab,2018,64(3):379-382.
[3]赵春莲,陈小霞,屈芳,等.PCT、CRP水平变化与剖宫产后产褥感染的相关性分析及其作用机制研究[J].中国医师杂志,2018,20(4):554-557.
[4]魏三舟,胡汉国.动态监测产褥感染产妇血清细胞因子及抗氧化能力指标的临床价值[J].中国计划生育和妇产科,2016,8(3):62-65.
[5]钟俊敏,冯艳,郑峥,等.血清降钙素原在诊断早期产褥感染中的意义[J].中国妇幼健康研究,2017,28(1):48-50.
[6]FERRARO F,PISELLI P,PITTALIS S,et al.Surgical site infection after caesarean section:space for post-dischar ge surveillance improvements and reliable comparisons[J].New Microbiol,2016,39(2):134-138.
[7]SHREE R,PARK SY,BEIGI RH,et al.Surgical site infection following cesarean delivery:patient,provider and procedure specific risk factors[J].Am J Perinatol,2016,33(2):157-164.
[8]贺利平,李晋琼,张瑛,等.不同分娩方式高危产妇产褥期感染相关因素及对新生儿的影响[J].中华医院感染学杂志,2018,28(12):1884-1887,1916.
[9]TITA AT,SZYCHOWSKI JM,BOGGESS K,et al.Adjunctive azithromycin prophylaxis for cesarean delivery[J].N Engl J Med,2016,375(13):1231-1241.
[10]KABOR魪B,SOUDOUEM G,SECK I,et al.A case-control study of risk factors for surgical site infection after cesarean delivery in eastern Burkina Faso[J].Int J Gynaecol Obstet,2016,135 Suppl 1:S107-S110.
[11]FISCHER-SU魣REZ N,FERN魣NDEZ-ALONSO AM,HERRERA-MU譙OZ A,et al.Maternal serum 25-hydroxyvitamin D and C-reactive protein levels in pregnancies complicated with threatened preterm labour[J].Gynecol Endocrinol,2016,32(9):777-781.
[12]SOSA ME.Group A streptococcal infection in pregnancy and the puerperium[J].J Perinat Neonatal Nurs,2016,30(2):124-130.
[13]李艺,郭静,郑多丽,等.不同分娩方式对产褥感染与血清白细胞计数和C反应蛋白及降钙素原水平的影响[J].中华医院感染学杂志,2017,27(7):1604-1607.
[14]杨佳,李长清.不同分娩方式产妇产褥期阴道微生态的变化及其影响因素[J].临床输血与检验,2016,18(3):254-258.
[2]CHEN Y,HAN X,GUO P,et al.Bacteramia caused by gardnerella vaginalis in a cesarean section patient[J].Clin Lab,2018,64(3):379-382.
[3]赵春莲,陈小霞,屈芳,等.PCT、CRP水平变化与剖宫产后产褥感染的相关性分析及其作用机制研究[J].中国医师杂志,2018,20(4):554-557.
[4]魏三舟,胡汉国.动态监测产褥感染产妇血清细胞因子及抗氧化能力指标的临床价值[J].中国计划生育和妇产科,2016,8(3):62-65.
[5]钟俊敏,冯艳,郑峥,等.血清降钙素原在诊断早期产褥感染中的意义[J].中国妇幼健康研究,2017,28(1):48-50.
[6]FERRARO F,PISELLI P,PITTALIS S,et al.Surgical site infection after caesarean section:space for post-dischar ge surveillance improvements and reliable comparisons[J].New Microbiol,2016,39(2):134-138.
[7]SHREE R,PARK SY,BEIGI RH,et al.Surgical site infection following cesarean delivery:patient,provider and procedure specific risk factors[J].Am J Perinatol,2016,33(2):157-164.
[8]贺利平,李晋琼,张瑛,等.不同分娩方式高危产妇产褥期感染相关因素及对新生儿的影响[J].中华医院感染学杂志,2018,28(12):1884-1887,1916.
[9]TITA AT,SZYCHOWSKI JM,BOGGESS K,et al.Adjunctive azithromycin prophylaxis for cesarean delivery[J].N Engl J Med,2016,375(13):1231-1241.
[10]KABOR魪B,SOUDOUEM G,SECK I,et al.A case-control study of risk factors for surgical site infection after cesarean delivery in eastern Burkina Faso[J].Int J Gynaecol Obstet,2016,135 Suppl 1:S107-S110.
[11]FISCHER-SU魣REZ N,FERN魣NDEZ-ALONSO AM,HERRERA-MU譙OZ A,et al.Maternal serum 25-hydroxyvitamin D and C-reactive protein levels in pregnancies complicated with threatened preterm labour[J].Gynecol Endocrinol,2016,32(9):777-781.
[12]SOSA ME.Group A streptococcal infection in pregnancy and the puerperium[J].J Perinat Neonatal Nurs,2016,30(2):124-130.
[13]李艺,郭静,郑多丽,等.不同分娩方式对产褥感染与血清白细胞计数和C反应蛋白及降钙素原水平的影响[J].中华医院感染学杂志,2017,27(7):1604-1607.
[14]杨佳,李长清.不同分娩方式产妇产褥期阴道微生态的变化及其影响因素[J].临床输血与检验,2016,18(3):254-258.