缺血性脑白质病的中医治疗进展
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摘要
为探讨中医在治疗缺血性脑白质病方面的相关研究,文章通过对近十年来缺血性脑白质病的相关研究文献分析,探讨该病的中医病因病机认识、治疗原则及中医具体的治疗方法。总结出本病主要以肾虚髓窍失养和痰瘀阻于脑络为主要病机,以补肾填精益髓和化痰活血通络为基本治疗原则,通过中药和针灸治疗均取得良好疗效,以期为临床治疗缺血性脑白质病提供思路和参考。
In order to discuss the related research of TCM in the treatment of ischemic leukoencephalopathy,this paper analyzes the related research literature of ischemic leukoencephalopathy in recent ten years and probes into the etiology,pathogenesis,treatment principle and specific treatment method of TCM. It is concluded that the main pathogenesis of this disease is kidney deficiency,insufficiency of marrow sea and obstruction of phlegm and stasis in brain collateral,and the basic treatment principles are tonifying the kidney,nourishing the bone marrow,removing phlegm and activating blood circulation. Good curative effect has been achieved through traditional Chinese medicine and acupuncture therapy,hoping to provide the reference for clinical treatment of ischemic leukoencephalopathy.
In order to discuss the related research of TCM in the treatment of ischemic leukoencephalopathy,this paper analyzes the related research literature of ischemic leukoencephalopathy in recent ten years and probes into the etiology,pathogenesis,treatment principle and specific treatment method of TCM. It is concluded that the main pathogenesis of this disease is kidney deficiency,insufficiency of marrow sea and obstruction of phlegm and stasis in brain collateral,and the basic treatment principles are tonifying the kidney,nourishing the bone marrow,removing phlegm and activating blood circulation. Good curative effect has been achieved through traditional Chinese medicine and acupuncture therapy,hoping to provide the reference for clinical treatment of ischemic leukoencephalopathy.
引文
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[11]李含章,王筱薇,袁岳鹏,等.中医综合干预对脑白质疏松症并脑梗死患者预后的影响[J].中国实验方剂学杂志,2012,18(23):336-338.
[12]王谦.缺血性脑白质疏松症性眩晕的症候要素特征研究[D].北京:北京中医药大学,2014:40-45.
[13]李洪海.化瘀通络合剂对脑小血管病致认知功能障碍的功能网络研究[D].广州:广州中医药大学,2016:10-30.
[14]葛玉杰.培元开智汤治疗脑小血管病性认知功能障碍的临床研究[D].郑州:河南中医药大学,2016:19-35.
[15]郜风清,籍玉红,曹红格,等.通脉益智胶囊配合针灸治疗脑小血管病所致认知障碍的疗效及对TXA2、PGI2、ET及Hcy的影响[J].现代中西医结合杂志,2017,26(34):3841-3843.
[16]历金财,罗清杰,赵雪玲,等.通神复脑丸对脑小血管病认知障碍患者C-反应蛋白、D-二聚体的影响[J].中国中医药现代远程教育,2016,14(12):64-66.
[17]谢克航.不同黄芪剂量的补阳还五汤对脑小血管病hsCRP、HCY的影响[D].广州:广州中医药大学,2016:1-23.
[18]卢要强.柴芩温胆汤治疗脑小血管病性认知功能障碍的临床观察[J].光明中医,2017,32(21):3094-3095.
[19]马卫琴,缪晓明,李碧青,等.加味柴胡疏肝汤治疗脑小血管病合并肝气郁结型郁病40例[J].湖南中医杂志,2015,31(11):62-63.
[20]刁丽丹.脑复康联用补阳还五汤加减治疗脑血管痴呆的临床观察[J].中西医结合中国民间疗法,2017,25(12):66-67.
[21]谭赛,黄世敬.川芎对血管性抑郁症的脑保护作用[J].环球中医药,2015,8(4):492-495.
[22]唐艳艳.天麻素联合依达拉奉注射液治疗脑小血管病引起的眩晕的疗效观察[J].黑龙江中医药,2011,40(1):10-11.
[23]孙梦云,黄世敬.血管性抑郁症的中药治疗进展[J].辽宁中医杂志,2017,44(4):887-889.
[24]张骐,陈爱霞,陈燕,等.银杏酮酯分散片治疗脑小血管病所致轻度认知障碍的疗效观察[J].中西医结合心脑血管病杂志,2014,12(10):1231-1232.
[25]马海涵,邵志成,邵阳.何首乌对血管性痴呆患者血液流变学作用研究[J].中外医疗,2014,33(32):30-31,33.
[26]李丹,王中鹏,周培娟.两种针刺时程对脑白质疏松轻度认知障碍患者的影响[J].陕西中医,2015,43(3):69-71.
[27]潘良.白质疏松型轻度认知障碍的针刺干预频次研究[D].北京:北京中医药大学,2012:17-49.
[28]李丹,王中鹏,周培娟.针刺治疗脑白质疏松症的评估方法评述[J].中医药学报,2013,41(5):85-87.
[29]侯小兵.针刺对脑白质疏松轻度认知障碍功能磁共振的影响[D].北京:北京中医药大学,2009:12-13.
[30]张京兰,王非,杨晶,等.耳穴电针治疗对脑小血管病伴抑郁患者的疗效评价[J].云南中医学院学报,2017,40(3):69-72.
[2]田金洲.王永炎院士查房实录[M].北京:人民卫生出版社,2015:16-20.
[3]黄世敬,王永炎.培元通滞治疗缺血性脑白质病思路探讨[J].中国中医基础医学杂志,2012,18(2):173-174.
[4]黄鹏展,迟晓玲,邱海丽,等.益肾通络化浊汤治疗缺血性脑白质病轻度认识障碍的临床观察[J].中国中医药科技,2017,24(5):640-641.
[5]李王杏安,张献文,况时祥.脑通胶囊治疗脑白质疏松症40例疗效观察[J].湖南中医杂志,2014,30(2):27-28.
[6]王蕾,姬琳,王兴臣,等.清脑益智颗粒干预脑白质疏松症轻度认知障碍记忆损害的临床研究[J].山东中医药大学学报,2012,36(4):302-303.
[7]孟胜喜,霍清萍.从肾论治脑小血管病[J].中西医结合心脑血管病杂志,2016,11(11):1212-1215.
[8]孟旭.通络益智汤联合西药治疗缺血性脑白质疏松症的临床研究[J].四川中医,2017,35(7):138-140.
[9]丁辉燕.复方苁蓉益智胶囊联合奥拉西坦治疗脑白质疏松认知障碍疗效观察[J].陕西中医,2017,38(8):991-992.
[10]韩英华,刘丽达,王蕾.清脑益智颗粒对脑白质疏松症轻度认知障碍患者的疗效及作用机制[J].中国医院药学杂志,2014,34(18):1582-1585.
[11]李含章,王筱薇,袁岳鹏,等.中医综合干预对脑白质疏松症并脑梗死患者预后的影响[J].中国实验方剂学杂志,2012,18(23):336-338.
[12]王谦.缺血性脑白质疏松症性眩晕的症候要素特征研究[D].北京:北京中医药大学,2014:40-45.
[13]李洪海.化瘀通络合剂对脑小血管病致认知功能障碍的功能网络研究[D].广州:广州中医药大学,2016:10-30.
[14]葛玉杰.培元开智汤治疗脑小血管病性认知功能障碍的临床研究[D].郑州:河南中医药大学,2016:19-35.
[15]郜风清,籍玉红,曹红格,等.通脉益智胶囊配合针灸治疗脑小血管病所致认知障碍的疗效及对TXA2、PGI2、ET及Hcy的影响[J].现代中西医结合杂志,2017,26(34):3841-3843.
[16]历金财,罗清杰,赵雪玲,等.通神复脑丸对脑小血管病认知障碍患者C-反应蛋白、D-二聚体的影响[J].中国中医药现代远程教育,2016,14(12):64-66.
[17]谢克航.不同黄芪剂量的补阳还五汤对脑小血管病hsCRP、HCY的影响[D].广州:广州中医药大学,2016:1-23.
[18]卢要强.柴芩温胆汤治疗脑小血管病性认知功能障碍的临床观察[J].光明中医,2017,32(21):3094-3095.
[19]马卫琴,缪晓明,李碧青,等.加味柴胡疏肝汤治疗脑小血管病合并肝气郁结型郁病40例[J].湖南中医杂志,2015,31(11):62-63.
[20]刁丽丹.脑复康联用补阳还五汤加减治疗脑血管痴呆的临床观察[J].中西医结合中国民间疗法,2017,25(12):66-67.
[21]谭赛,黄世敬.川芎对血管性抑郁症的脑保护作用[J].环球中医药,2015,8(4):492-495.
[22]唐艳艳.天麻素联合依达拉奉注射液治疗脑小血管病引起的眩晕的疗效观察[J].黑龙江中医药,2011,40(1):10-11.
[23]孙梦云,黄世敬.血管性抑郁症的中药治疗进展[J].辽宁中医杂志,2017,44(4):887-889.
[24]张骐,陈爱霞,陈燕,等.银杏酮酯分散片治疗脑小血管病所致轻度认知障碍的疗效观察[J].中西医结合心脑血管病杂志,2014,12(10):1231-1232.
[25]马海涵,邵志成,邵阳.何首乌对血管性痴呆患者血液流变学作用研究[J].中外医疗,2014,33(32):30-31,33.
[26]李丹,王中鹏,周培娟.两种针刺时程对脑白质疏松轻度认知障碍患者的影响[J].陕西中医,2015,43(3):69-71.
[27]潘良.白质疏松型轻度认知障碍的针刺干预频次研究[D].北京:北京中医药大学,2012:17-49.
[28]李丹,王中鹏,周培娟.针刺治疗脑白质疏松症的评估方法评述[J].中医药学报,2013,41(5):85-87.
[29]侯小兵.针刺对脑白质疏松轻度认知障碍功能磁共振的影响[D].北京:北京中医药大学,2009:12-13.
[30]张京兰,王非,杨晶,等.耳穴电针治疗对脑小血管病伴抑郁患者的疗效评价[J].云南中医学院学报,2017,40(3):69-72.