多囊卵巢综合征妊娠患者中药早期干预临床研究
|
摘要
目的:探讨多囊卵巢综合征妊娠患者中药早期干预的临床疗效。方法:收集多囊卵巢综合征妊娠患者72例,分为试验组和对照组,各36例。试验组在诊断妊娠后即予中药口服维持妊娠,对照组予中药安慰剂,观察两组的腰酸、腹痛发生率、唐氏筛查及胎儿颈项透明层检查(NT检查)异常发生率。结果:试验组腰酸、腹痛、腰酸合并腹痛的发生率与对照组无明显差异,但总症状发生率试验组较对照组明显降低,具有统计学意义。其中腰酸合并腹痛患者更易发展为先兆流产。试验组先兆流产率较对照组降低,具有统计学意义,两组早期唐筛、NT异常率差异无统计学意义。结论:对于多囊卵巢综合征妊娠患者,中药早期干预可减少妊娠早期不适,减少早期妊娠丢失,此外该类患者常伴焦虑、抑郁情绪障碍,更应重视平心定气以养胎。
Objective: To explore the clinical effect of early intervention of Traditional Chinese medicine(TCM) for pregnant with polycystic ovary syndrome. Methods: 72 pregnant with polycystic ovary syndrome are divided into test group and control group. Each group contains 36 cases.The test group was given TCM to maintain pregnancy. The control group given placebo.To observe the Incidence of lumbago, abdominal pain, down screening and NT. Results: There are no difference in the lumbago, abdominal pain between the test and control group.All of lumbago, abdominal pain,there is significant difference. Patients with lumbar acid and abdominal pain are more likely to develop a threatened abortion. The rate of threatened abortion in test group is much lower than in control group. There are no difference in down screening and NT between test and control group. Conclusion: Early intervention of TCM to reduce early pregnancy discomfort and the rate of threatened abortion. It is important to keep a good mood for pregnant with polycystic ovary syndrome.
Objective: To explore the clinical effect of early intervention of Traditional Chinese medicine(TCM) for pregnant with polycystic ovary syndrome. Methods: 72 pregnant with polycystic ovary syndrome are divided into test group and control group. Each group contains 36 cases.The test group was given TCM to maintain pregnancy. The control group given placebo.To observe the Incidence of lumbago, abdominal pain, down screening and NT. Results: There are no difference in the lumbago, abdominal pain between the test and control group.All of lumbago, abdominal pain,there is significant difference. Patients with lumbar acid and abdominal pain are more likely to develop a threatened abortion. The rate of threatened abortion in test group is much lower than in control group. There are no difference in down screening and NT between test and control group. Conclusion: Early intervention of TCM to reduce early pregnancy discomfort and the rate of threatened abortion. It is important to keep a good mood for pregnant with polycystic ovary syndrome.
引文
[1]Moreira S,Soares E,Tomaz G,et al.Polycystic ovary syndrome:a psychosocial approach[J].Acta Med Port,2010,23(2):237-242.
[2]张信贤,郭影,单晓微,等.多囊卵巢综合征与复发性流产的研究进展[J].生殖医学杂志,2017,26(5):494-497
[3]乔杰,尹太郎.多囊卵巢综合征认识与对策[J].中华实用妇科与产科杂志,2013,29(11):841
[4]GLUECK C J,PHILLIPS H,CAMERON D,et al.Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce fst-trimester spontaneous abortion:a pilot study[J].Fertil Steril,2001,75(1):46-52.
[5]FORNES R,ORMAZABALP,ROSASC,et al.Changes in the expression of insulin signaling pathway molecules in endometria from polycystic ovary syndrome women with or without hyperinsulinemia[J].MolMed,2010,16(3/4):129-136.
[6]吴敏,陆启滨.补肾健脾法治疗复发性流产的机理研究[J].中国中西医结合杂志,2014,34(1):106-108.
[7]郑瑞芹,刘晓芹,张建英.PCOS患者早期自然流产与子宫内膜雌孕激素受体的关系及中西医结合治疗[J].中国计划生育学杂志,2011,19(5):294
[8]李素文,田金华,吴月芳,等.多囊卵巢综合征的心理健康与心理疏导[J].河北医药,2011,33(23):3664-3665.
[2]张信贤,郭影,单晓微,等.多囊卵巢综合征与复发性流产的研究进展[J].生殖医学杂志,2017,26(5):494-497
[3]乔杰,尹太郎.多囊卵巢综合征认识与对策[J].中华实用妇科与产科杂志,2013,29(11):841
[4]GLUECK C J,PHILLIPS H,CAMERON D,et al.Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce fst-trimester spontaneous abortion:a pilot study[J].Fertil Steril,2001,75(1):46-52.
[5]FORNES R,ORMAZABALP,ROSASC,et al.Changes in the expression of insulin signaling pathway molecules in endometria from polycystic ovary syndrome women with or without hyperinsulinemia[J].MolMed,2010,16(3/4):129-136.
[6]吴敏,陆启滨.补肾健脾法治疗复发性流产的机理研究[J].中国中西医结合杂志,2014,34(1):106-108.
[7]郑瑞芹,刘晓芹,张建英.PCOS患者早期自然流产与子宫内膜雌孕激素受体的关系及中西医结合治疗[J].中国计划生育学杂志,2011,19(5):294
[8]李素文,田金华,吴月芳,等.多囊卵巢综合征的心理健康与心理疏导[J].河北医药,2011,33(23):3664-3665.