心肌型脂肪酸结合蛋白在急性心肌梗死早期诊断中的价值
|
摘要
目的观察心型脂肪酸结合蛋白(H-FABP)诊断早期急性心肌梗死(AMI)的效果。方法选择我院收治的150例AMI患者为观察组,并选择同期150例健康体检者为对照组。两组均测定H-FABP、心肌肌钙蛋白I(c Tn I)以及肌酸激酶同工酶(CK-MB)水平。结果观察组胸痛发作不同时间段内H-FABP水平均高于对照组(P<0.05);观察组内H-FABP诊断敏感性、特异性等指标优于c Tn I、CK-MB(P<0.05)。结论 H-FABP检测早期AMI准确度高。
Objective To observe the effect of H-FABP in the diagnosis of early AMI. Methods 150 AMI patients were selected as observation group, and 150 healthy subjects were selected as control group. The levels of H-FABP, cardiac troponin I(cTnI) and creatine kinase isoenzyme(CKMB)were measured between two groups. Results The level of H-FABP in different periods of chest pain of observation group was significantly higher than control group(P < 0.05). The sensitivity and negative predictive value of H-FABP in the observation group were significantly better than cTnI and CK-MB(P < 0.05). Conclusion H-FABP has high accuracy in early detection of AMI.
Objective To observe the effect of H-FABP in the diagnosis of early AMI. Methods 150 AMI patients were selected as observation group, and 150 healthy subjects were selected as control group. The levels of H-FABP, cardiac troponin I(cTnI) and creatine kinase isoenzyme(CKMB)were measured between two groups. Results The level of H-FABP in different periods of chest pain of observation group was significantly higher than control group(P < 0.05). The sensitivity and negative predictive value of H-FABP in the observation group were significantly better than cTnI and CK-MB(P < 0.05). Conclusion H-FABP has high accuracy in early detection of AMI.
引文
[1]王恒秋,刘雨峰,王双.三种心肌标志物对诊断急性心肌梗死的价值[J].实验与检验医学,2014,32(6):775-777.
[2]齐洪娜,张建军,何佳起,等.心型脂肪酸结合蛋白和N-末端脑钠肽前体在脓毒症心肌损伤中的变化及意义[J].实用医学杂志,2016,32(17):2957-2860.
[3]林高贵,孟凡超,曾云祥,等.心型脂肪酸结合蛋白在急性心肌梗死早期诊断中的价值[J].检验医学,2012,27(14):280-285.
[4]司煜安.血清心肌型脂肪酸结合蛋白检测在急性心肌梗死诊断中的应用[J].检验医学与临床,2012,9(7):818-819.
[5]闫福堂,袁军,张艳,等.心型脂肪酸结合蛋白的临床应用研究[J].国际检验医学杂志,2012,33(12):1432-1433.
[6]夏杰.快速检测血浆心肌脂肪酸结合蛋白(H-FABP)在急性心肌梗死早期诊断中的临床价值[J].中国民康医学,2014,27(7):61-62.
[7]周晓茜,蔡英,于萍,等.心型脂肪酸结合蛋白在急性心肌梗死早期诊断价值的研究[J].中国急救医学,2013,33(3):212-215.
[8]王亚蓉,郭壮波,黄丽萍.三种心肌损伤标志物对早期急性心肌梗死的诊断价值[J].南方医科大学学报,2014,34(9):1347-1350.
[2]齐洪娜,张建军,何佳起,等.心型脂肪酸结合蛋白和N-末端脑钠肽前体在脓毒症心肌损伤中的变化及意义[J].实用医学杂志,2016,32(17):2957-2860.
[3]林高贵,孟凡超,曾云祥,等.心型脂肪酸结合蛋白在急性心肌梗死早期诊断中的价值[J].检验医学,2012,27(14):280-285.
[4]司煜安.血清心肌型脂肪酸结合蛋白检测在急性心肌梗死诊断中的应用[J].检验医学与临床,2012,9(7):818-819.
[5]闫福堂,袁军,张艳,等.心型脂肪酸结合蛋白的临床应用研究[J].国际检验医学杂志,2012,33(12):1432-1433.
[6]夏杰.快速检测血浆心肌脂肪酸结合蛋白(H-FABP)在急性心肌梗死早期诊断中的临床价值[J].中国民康医学,2014,27(7):61-62.
[7]周晓茜,蔡英,于萍,等.心型脂肪酸结合蛋白在急性心肌梗死早期诊断价值的研究[J].中国急救医学,2013,33(3):212-215.
[8]王亚蓉,郭壮波,黄丽萍.三种心肌损伤标志物对早期急性心肌梗死的诊断价值[J].南方医科大学学报,2014,34(9):1347-1350.