健康中老年人不同年龄段左腕脉搏波传导时间参考值的建立
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摘要
目的初步估计健康中老年人左腕脉搏波传导时间(Pulse Wave Transit Time,PWTT)所在的参考值范围,为早期预测血管硬化提供依据。方法采用便利抽样法对我院门诊1288例健康中老年通过智能腕表采集左腕脉搏波传导时间进行统计分析。结果 35~44岁组:95%置信区间(Confidence Interval,CI)为(186,192)ms;45~59岁组:男性95%CI(180,186)ms,女性95%CI(185,190)ms;60~89岁组95%CI(177,183)ms;经3组方差分析,F=10.200,P<0.05;3组间PWTT存在显著性差异,再进行组间的两两比较均具有统计学意义(P<0.05),其中45~59岁组较35~44岁组缩短4 ms,60~89岁组较45~59岁组缩短5 ms。结论健康中老年人随着年龄的增长,动脉硬化程度逐渐加重,且年龄越大,动脉硬化的速度越快。
Objective To estimate the normal range of pulse wave transit time(PWTT) about the middle aged and elderly people, and to provide the basis for the prediction of the vascular sclerosis at early stage. Methods The convenience sampling method was adopted in our hospital outpatient, and 1288 cases of healthy middle aged and elderly people were recruited into this research. The PWTT collected by smart watch was analyzed statistically. Results The 95% confidence interval(CI) ranged from 186 to 192 ms in group 35~44; The 95% CI of men ranged from 180 to 186 ms, and women ranged from 185 to 190 ms in group 45~59; The 95% CI ranged group from 177 to 183 ms in 60~89. The difference among these three groups was significant(P<0.05); group 45~59 was 4 ms shorter than that of the group 35~44(P<0.05); group 60~89 was 5 ms shorter than that of the group 45~59. Conclusion The degree of arteriosclerosis in middle aged and elderly people gradually increases with age, and the older the age, the faster the arteriosclerosis.
Objective To estimate the normal range of pulse wave transit time(PWTT) about the middle aged and elderly people, and to provide the basis for the prediction of the vascular sclerosis at early stage. Methods The convenience sampling method was adopted in our hospital outpatient, and 1288 cases of healthy middle aged and elderly people were recruited into this research. The PWTT collected by smart watch was analyzed statistically. Results The 95% confidence interval(CI) ranged from 186 to 192 ms in group 35~44; The 95% CI of men ranged from 180 to 186 ms, and women ranged from 185 to 190 ms in group 45~59; The 95% CI ranged group from 177 to 183 ms in 60~89. The difference among these three groups was significant(P<0.05); group 45~59 was 4 ms shorter than that of the group 35~44(P<0.05); group 60~89 was 5 ms shorter than that of the group 45~59. Conclusion The degree of arteriosclerosis in middle aged and elderly people gradually increases with age, and the older the age, the faster the arteriosclerosis.
引文
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[18]马孝湘,陈晓平,程幼夫,等.绝经后女性高血压患者血压水平与雌激素、糖化血红蛋白的相关性[J].中华高血压杂志,2014,(10):974-976.
[2]吴全玉,刘晓杰,姚克明,等.全桡动脉波传导时间与动脉硬化参数的对比分析研究[J].应用力学学报,2016,(2):229-233.
[3]张鑫,洪必莹,陈晓平,等.不同性别高血压患者脉搏波传导速度影响因素研究[J].西部医学,2016,(3):346-350.
[4]赵清水,张琼,黄少平.北京市房山区农村中老年人群颈动脉硬化及其影响因素的分析[J].中国慢性病预防与控制,2012,(6):701-703.
[5]阮力,曲淑珍,李卫平,等.颈动脉硬化与相关因素分析[J].中国预防医学杂志,2008,(10):917-919.
[6]温胜男.原发性高血压动脉硬化及相关遗传因素的研究[D].济南:山东省医学科学院,2009.
[7]陈珮,王斌,周晓燕,等.原发性高血压患者AIP与PWV及动脉硬化相关危险因素关系的研究[J].慢性病学杂志,2016,(7):728-730.
[8]刘圣好,潘文博,钟万生,等.原发性高血压患者脉搏波传导速度的影响因素[J].中华高血压杂志,2011,(3):283-285.
[9]潘慧,路方红,赵颖馨,等.血压正常高值者中心动脉压及其反射波与动脉弹性相关[J].中华高血压杂志,2010,(8):774-778.
[10]Boǐtsov SA SA,Rogoza AN,Kanishcheva E,et al.Increased arterial stiffness is a significant but not obligatory factor of arterial hypertension in persons over 60 years of age[J].Ter Arkh,2011,83(9):5-9.
[11]孙尚文,路方红,赵颖馨,等.老年高血压患者动态血压负荷和脉搏波传导速度的相关性研究[J].中华老年心脑血管病杂志,2012,(7):687-690.
[12]牟文英,陈善广,李钰.脉搏波速度与性别关系的研究分析[J].航天医学与医学工程,2012,(6):454-457.
[13]沈英豪,张俊峰,周静,等.性别、年龄、BMI对高血压患者动脉僵硬度的影响[J].中国医师杂志,2013,15(4):465-468.
[14]程育博.臂踝脉搏波速度对冠状动脉粥样硬化预测的性别差异分析[J].中西医结合心脑血管病杂志,2010,(8):1000-1001.
[15]Segers P,Rietzschel ER,De Buyzere ML,et al.Noninvasive(input)impedance,pulse wave velocity,and wave reflection in healthy middle-aged men and women[J].Hypertension,2007,49(6):1248-1255.
[16]Vermeersch SJ,Rietzschel ER,De Buyzere ML.Age and gender related patterns in carotid-femoral PWV and carotid and femoral stiffness in a large healthy,middle-aged population[J].J Hypertens,2008,26(7):1411-1419.
[17]石学宁.老年前期与老年期男性冠心病患者性激素水平的变化[J].宁夏医学院学报,1994,(4):357-358.
[18]马孝湘,陈晓平,程幼夫,等.绝经后女性高血压患者血压水平与雌激素、糖化血红蛋白的相关性[J].中华高血压杂志,2014,(10):974-976.