床旁肺脏超声评估新生儿肺透明膜病严重程度
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摘要
目的探讨床旁肺脏超声在评估新生儿肺透明膜病(hyaline membrane disease,HMD)严重程度的价值。方法对49例HMD患儿行床旁肺脏超声检查,并行肺超声评分,比较不同程度HMD患儿肺超声总评分差异,检验HMD患儿肺超声总评分与其氧合指数(PaO_2/FiO_2)关系。结果轻度与重度HMD患儿间肺超声总评分差异有统计学意义(P<0.01),肺超声总评分与PaO_2/FiO_2呈负相关(r=-0.881,P<0.01)。结论肺脏超声可反映新生儿HMD治疗前病情严重程度,有望成为评价HMD病情的新方法。
Objective To assess the value of the bed side lung ultrasound in evaluating neonatal hyaline membrane disease( HMD). Methods 49 cases of neonatal HMD were examined with bed side lung ultrasound,the difference of the lung ultrasound score in different degrees of HMD was compared and the relationship between the lung ultrasound score and oxygenation index( PaO_2/FiO_2) was tested. Results The difference of lung ultrasound score between mild and severe HMD was statistically significant,and the lung ultrasound score was negatively correlation with PaO_2/FiO_2. Conclusion The lung ultrasound can reflect the severity of neonatal HMD,which is expected to become a new method to evaluate the disease condition of HMD.
Objective To assess the value of the bed side lung ultrasound in evaluating neonatal hyaline membrane disease( HMD). Methods 49 cases of neonatal HMD were examined with bed side lung ultrasound,the difference of the lung ultrasound score in different degrees of HMD was compared and the relationship between the lung ultrasound score and oxygenation index( PaO_2/FiO_2) was tested. Results The difference of lung ultrasound score between mild and severe HMD was statistically significant,and the lung ultrasound score was negatively correlation with PaO_2/FiO_2. Conclusion The lung ultrasound can reflect the severity of neonatal HMD,which is expected to become a new method to evaluate the disease condition of HMD.
引文
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[5]王艺萍,肖菲,黎嘉嘉,等.床旁超声指导设定重度急性呼吸窘迫综合征患者的通气时间[J].中华医学杂志,2015,95(15):1448-1452.
[6]刘敬,曹海英,刘颖.肺脏超声对新生儿呼吸窘迫综合征的诊断价值[J].中华儿科杂志,2013,51(3):205-210.
[7]刘敬.肺脏超声诊断新生儿呼吸窘迫综合征[J].中华实用儿科临床杂志,2014,29(18):1438-1440.
[8]李莲花,杨倩,李黎明,等.肺部超声评分评估急性呼吸窘迫综合征患者病情严重程度及预后的价值[J].中华危重病急救医学,2015,27(7):579-584.
[2]Gargani L,Lionetti V,Di Cristofano C,et al.Early detection of acute lung injury uncoupled to hypoxemia in pigs using ultrasound lung comets[J].Crit Care Med,2007,35(12):2769-2774.
[3]Soummer A,Perbet S,Brisson H,et al.Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress[J].Crit Care Med,2012,40(7):2064-2072.
[4]吕发勤,黎檀实.超声技术在急性呼吸窘迫综合征诊治中的应用前景[J].中华急诊医学杂志,2014,23(3):255-256.
[5]王艺萍,肖菲,黎嘉嘉,等.床旁超声指导设定重度急性呼吸窘迫综合征患者的通气时间[J].中华医学杂志,2015,95(15):1448-1452.
[6]刘敬,曹海英,刘颖.肺脏超声对新生儿呼吸窘迫综合征的诊断价值[J].中华儿科杂志,2013,51(3):205-210.
[7]刘敬.肺脏超声诊断新生儿呼吸窘迫综合征[J].中华实用儿科临床杂志,2014,29(18):1438-1440.
[8]李莲花,杨倩,李黎明,等.肺部超声评分评估急性呼吸窘迫综合征患者病情严重程度及预后的价值[J].中华危重病急救医学,2015,27(7):579-584.