健脑通胶囊治疗老年痴呆临床观察
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摘要
目的观察健脑通胶囊对老年痴呆患者的临床疗效及对超氧化物歧化酶(SOD)含量的影响。方法选取老年痴呆患者共118例,随机分为两组,均给予基础治疗,包括宣教,饮食调节,控制血压、血脂、血糖等,保证患者正常健康的生活。对照组不服用任何对老年痴呆起效的药物。治疗组给予健脑通胶囊1.5g口服,每日3次。180d后观察疗效。结果治疗组的总有效率明显高于对照组(P<0.01)。两组治疗后SOD含量均比治疗前SOD的含量要高(P<0.01),治疗组SOD的含量要比对照组高(P<0.01)。结论健脑通胶囊能够提高患者血清中SOD含量,改善患者智力,对老年痴呆治疗效果明显。
Objective To observe the clinical efficacy of Jiannaotong capsule on Alzheimer's disease and its effect on superoxide dismutase( SOD) content. Methods 118 patients with Alzheimer's disease were randomly divided into 2 groups,59 cases in each group,both groups were given basic treatment,including propaganda and education,diet control,blood pressure control,blood lipid,blood sugar control to ensure the normal and healthy life of patients. The control group took no drugs for Alzheimer's disease. Treatment group was given brain capsule orally,3 times per day,observe the result after 180 d of treatment. Results SOD contents in both groups after treatment were higher than those of before treatment with stastically significance( P < 0. 05). Compared with control group,the content of SOD in treatment group was higher than that of the control group( P < 0. 02). After 6 months of treatment,the effective rate of treatment group was 91. 52%,higher than 76. 27% of control group. Conclusion Jiannaotong capsule can improve the content of serum SOD as well as the intelligence of patients.
Objective To observe the clinical efficacy of Jiannaotong capsule on Alzheimer's disease and its effect on superoxide dismutase( SOD) content. Methods 118 patients with Alzheimer's disease were randomly divided into 2 groups,59 cases in each group,both groups were given basic treatment,including propaganda and education,diet control,blood pressure control,blood lipid,blood sugar control to ensure the normal and healthy life of patients. The control group took no drugs for Alzheimer's disease. Treatment group was given brain capsule orally,3 times per day,observe the result after 180 d of treatment. Results SOD contents in both groups after treatment were higher than those of before treatment with stastically significance( P < 0. 05). Compared with control group,the content of SOD in treatment group was higher than that of the control group( P < 0. 02). After 6 months of treatment,the effective rate of treatment group was 91. 52%,higher than 76. 27% of control group. Conclusion Jiannaotong capsule can improve the content of serum SOD as well as the intelligence of patients.
引文
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[12]张连城,张玉莲,张权.从肾藏精论治老年痴呆[J].中医杂志,2011,52(17):1456-1458.
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[14]王玉璧,郭蕾,窦志芳,等.关于老年痴呆病的中医病因病机探讨[J].中华中医药学刊,2011,29(04):743-745.
[15]苗琦,王郁金.健脑通胶囊延缓老年痴呆发展临床观察[J].吉林中医药,2013,33(10):1012-1015.
[2]马宁,边瓯.老年痴呆营养干预的研究现状[J].中国老年学杂志,2015,35(16):4711-4712.
[3]石景洋,付卫云,李凤芝,等.治疗老年痴呆中药应用频次及临床分析[J].中国实验方剂学杂志,2013,4(8):12-13.
[4]彭计红,梅晓云,张同远.老年期痴呆从脑辩证规律[J].长春中医药大学学报,2011,27(6):954-956.
[5]傅仁杰.老年痴呆病诊断、辨证分型及疗效评定标准[J].中医杂志,1991,32(2):56.
[6]苗琦,张金培.健脑通胶囊对AD大鼠学习记忆及脂质过氧化氢酶影响的实验研究[J].陕西中医,2013,34(9):1261-1263.
[7]杨红,朱德生.盐酸多奈哌齐治疗老年痴呆的疗效研究[J].中国全科医学,2013,16(3):863-866.
[8]钱超,姜亚军.中西医结合治疗老年性痴呆112例临床观察[J].长春中医药大学学报,2012,28(2):307-308.
[9]张雪红.乙酰胆碱酶抑制剂类药物联合盐酸美金刚治疗老年痴呆临床疗效[J].中国老年学杂志,2013,2(19):25-26.
[10]苗琦.脑通胶囊治疗老年痴呆患者30例[J].陕西中医,2013,34(10):1299-1301.
[11]何静.健脾益气、滋阴益肾法治疗老年痴呆症临床观察[J].辽宁中医药大学学报,2013,15(5):178-179.
[12]张连城,张玉莲,张权.从肾藏精论治老年痴呆[J].中医杂志,2011,52(17):1456-1458.
[13]张艳霞,张允岭.基于现代文献的老年性痴呆证型及证候要素分布研究[J].北京中医药大学学报,2011,34(6):417-420.
[14]王玉璧,郭蕾,窦志芳,等.关于老年痴呆病的中医病因病机探讨[J].中华中医药学刊,2011,29(04):743-745.
[15]苗琦,王郁金.健脑通胶囊延缓老年痴呆发展临床观察[J].吉林中医药,2013,33(10):1012-1015.