自体口腔黏膜微粒联合脱细胞异体真皮基质再造阴道的临床探讨
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摘要
目的自体口腔黏膜微粒联合ADM(脱细胞异体真皮基质)再造阴道的临床探讨。方法择本院2009年11月-2015年11月收治的先天性无阴道的81例患者资料实施回顾性的分析,对所有患者联合实施口腔黏膜微粒与ADM再造阴道法,观察术后患者再造阴道的上皮化及脱离磨具时间,且在治疗后1年实施再造阴道的容积、周径及深度的测量,评定患者的性生活质量。结果所有患者的手术治疗皆已成功,经随访得知,再造阴道的上皮化时间是(10.28±3.24)d;再造阴道的容积是(110.12±11.21)m L;其中68例存在性生活的患者FSFI分数是(31.39±2.85)分。结论自体口腔黏膜微粒与脱细胞异体真皮基质联合再造阴道效果佳。
Objective To explore the clinical effect of autogenous oral mucosal microparticles combined with ADM(acellular dermal matrix) on reconstruction of the vagina. Methods The data of 81 patients with congenital absence of vagina admitted from November 2009 to November 2015 in our hospital were retrospectively analyzed. All the patients were treated with oral mucosal microparticles combined with ADM to rebuild the vagina, Vaginal epithelialization and out of the abrasive time, and in the treatment of vaginal reconstruction 1 year after the implementation of volume, circumference and depth measurements to assess the quality of sexual life of patients. Results Surgical treatment was successful in all patients. The follow-up showed that the time to re-establish the vagina was(10.28±3.24) days and the volume of the vagina was(110.12±11.21) m L. Among 68 patients with sexual life The FSFI score was(31.39±2.85) points. Conclusion The combination of autologous oral mucosal micro-particles and acellular dermal matrix is good for vaginal reconstruction.
Objective To explore the clinical effect of autogenous oral mucosal microparticles combined with ADM(acellular dermal matrix) on reconstruction of the vagina. Methods The data of 81 patients with congenital absence of vagina admitted from November 2009 to November 2015 in our hospital were retrospectively analyzed. All the patients were treated with oral mucosal microparticles combined with ADM to rebuild the vagina, Vaginal epithelialization and out of the abrasive time, and in the treatment of vaginal reconstruction 1 year after the implementation of volume, circumference and depth measurements to assess the quality of sexual life of patients. Results Surgical treatment was successful in all patients. The follow-up showed that the time to re-establish the vagina was(10.28±3.24) days and the volume of the vagina was(110.12±11.21) m L. Among 68 patients with sexual life The FSFI score was(31.39±2.85) points. Conclusion The combination of autologous oral mucosal micro-particles and acellular dermal matrix is good for vaginal reconstruction.
引文
[1]李峰永,李森恺,周传德,等.自体口腔黏膜微粒联合脱细胞异体真皮基质再造阴道[J].中华整形外科杂志,2015,31(1):29-33.
[2]杨燕华.脱细胞异体真皮基质与口腔黏膜微粒复合移植再造阴道的护理[C].//2014中华医学会整形外科分会第十三次全国学术交流会论文集.2014:68-68.
[3]魏蜀一,李强,李森恺,等.阴囊皮瓣结合黏膜/皮肤微粒法再造阴道在男变女变性手术中的应用[J].中国美容整形外科杂志,2014,25(9):538-540.
[4]王娟,韩岩,贾宝庆,等.肠道行阴道再造术后并发症的处理及观察[J].中国美容整形外科杂志,2016,27(8):476-479.
[5]杨晓妮.先天性无阴道2例诊治比较[J].当代医学,2014,(10):68-69.
[6]张肖霄,张盈帆,刘蔡钺,等.女变男易性者行阴道黏膜预制尿道阴茎再造的临床效果[J].中华医学美学美容杂志,2017,23(2):99-102.
[7]胡珊,陈双郧,张春莲,等.腹腔镜下腹膜阴道成形术对阴道再造疗效的系统评价[J].中国美容整形外科杂志,2014,25(9):541-544.
[8]李秀丽,贾宝庆,韩岩,等.机器人带血管蒂回肠段移植阴道成形术:病例报告并文献复习[J].中华腔镜外科杂志(电子版),2014,(3):192-195.
[9]侯俊杰,马勇光,张洁,等.乙状结肠和口腔黏膜在MRKH患者阴道再造中的应用效果分析[J].中国美容医学,2017,26(9):15-18.
[10]周宇,李强,李森恺,等.脱细胞异体真皮与混合微粒复合移植再造阴道的临床疗效评价[C].2014中华医学会整形外科分会第十三次全国学术交流会论文集.2014:310.
[11]崔娇,张雪玉.先天性无阴道三种手术方式的临床疗效分析[J].宁夏医学杂志,2016,38(9):805-807.
[2]杨燕华.脱细胞异体真皮基质与口腔黏膜微粒复合移植再造阴道的护理[C].//2014中华医学会整形外科分会第十三次全国学术交流会论文集.2014:68-68.
[3]魏蜀一,李强,李森恺,等.阴囊皮瓣结合黏膜/皮肤微粒法再造阴道在男变女变性手术中的应用[J].中国美容整形外科杂志,2014,25(9):538-540.
[4]王娟,韩岩,贾宝庆,等.肠道行阴道再造术后并发症的处理及观察[J].中国美容整形外科杂志,2016,27(8):476-479.
[5]杨晓妮.先天性无阴道2例诊治比较[J].当代医学,2014,(10):68-69.
[6]张肖霄,张盈帆,刘蔡钺,等.女变男易性者行阴道黏膜预制尿道阴茎再造的临床效果[J].中华医学美学美容杂志,2017,23(2):99-102.
[7]胡珊,陈双郧,张春莲,等.腹腔镜下腹膜阴道成形术对阴道再造疗效的系统评价[J].中国美容整形外科杂志,2014,25(9):541-544.
[8]李秀丽,贾宝庆,韩岩,等.机器人带血管蒂回肠段移植阴道成形术:病例报告并文献复习[J].中华腔镜外科杂志(电子版),2014,(3):192-195.
[9]侯俊杰,马勇光,张洁,等.乙状结肠和口腔黏膜在MRKH患者阴道再造中的应用效果分析[J].中国美容医学,2017,26(9):15-18.
[10]周宇,李强,李森恺,等.脱细胞异体真皮与混合微粒复合移植再造阴道的临床疗效评价[C].2014中华医学会整形外科分会第十三次全国学术交流会论文集.2014:310.
[11]崔娇,张雪玉.先天性无阴道三种手术方式的临床疗效分析[J].宁夏医学杂志,2016,38(9):805-807.