发热中医机制的实验研究
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摘要
目的观察不同节气受寒大鼠体温的变化,探索发热的中医机制。方法分别在大雪、冬至、小寒节气给大鼠冰块受寒,连续观测肛温。结果冬至节气受寒的大鼠到立春节气出现体温升高(P<0.01)。结论冬至受寒是发热的中医机制之一。
Objective To explore the pyretic mechanism about T.C.M, observed by the wave of body temperature in rats frozen in different solar terms. Methods The rectal temperature is observed daily after rats are frozen by ice in the Great Snow, the Winter Solstice and the Slight Cold solar terms separately. Results The body temperature of rats frozen in the Winter Solstice rises by the beginning of Spring solar term(P<0.01). Conclusion It is one of the pyretic mechanisms of T.C.M. That frozen in Winter Solstice
Objective To explore the pyretic mechanism about T.C.M, observed by the wave of body temperature in rats frozen in different solar terms. Methods The rectal temperature is observed daily after rats are frozen by ice in the Great Snow, the Winter Solstice and the Slight Cold solar terms separately. Results The body temperature of rats frozen in the Winter Solstice rises by the beginning of Spring solar term(P<0.01). Conclusion It is one of the pyretic mechanisms of T.C.M. That frozen in Winter Solstice
引文
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[8]刘倩倩,张冀东,孙贵香.辨时论治发热的病理机制和诊疗思路[J].湖南中医药大学学报,2013,33(1):72.
[2] Lin X, kong J, Wu Q, et al. Effect of TLR4/MyD88 signaling pathway on expression of IL-1βand TNF-αin synovial fibroblasts from temproman dibular joint exposed to lipopolysaccharide[J]. Mediators Inflamm,2015,201(5):329.
[3] Piotrowska-Tomala KK,Siemieniuch MJ, Szostek.Lipopolysaccharides,cytokines and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland epithelial cells[J].Domest Anim Endocrinol, 2012,43(4):278.
[4] Sengupta T, Jaryal AK, Kumar VM, et al. L-glutamate microinjection in thepreoptic area increases brain and body temperature in freely moving rats[J].Neuoreport, 2014,25(1):28.
[5] Chang CH, Huang WT, Kao CH, et al. tetramethylpyrazine decreases hypothylamic glutamate, hydroxyl radicals and prostaglandin-E2 and has antipyretic effects[J].Inflamm Res,2013,62(5):527.
[6]全国第五次结核病流行病学抽样调查技术指导组,全国第五次结核病流行病学抽样调查办公室.2010年全国第五次结核病流行病学抽样调查报告[J].中国防痨杂志,2012,8(34):485.
[7]崔文秋.青蒿鳖甲汤治疗耐药肺结核发热的疗效观察[J].中西医结合心血管病杂志,2016,4(9):105.
[8]刘倩倩,张冀东,孙贵香.辨时论治发热的病理机制和诊疗思路[J].湖南中医药大学学报,2013,33(1):72.