妇科消囊汤联合西药治疗卵巢囊肿随机平行对照研究
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摘要
[目的]观察妇科消囊汤联合西药治疗卵巢囊肿疗效。[方法]使用随机平行对照方法,将70例门诊患者按就诊顺序号抽签随机分为两组。对照组30例头孢呋辛1.5g、奥硝唑0.5g+生理盐水250mL,静滴,2次/d。治疗组40例妇科消囊汤(鹿角霜、黄芪、白术、茯苓、菟丝子各18g,巴戟天、桂枝、丹参、鱼腥草各13g,甘草炙8g),水煎300mL,100mL/次,早晚分服;100mL加热至38℃,睡前排便后,灌肠袋衔接一次性肛管,石蜡油润滑后经由肛门插进直肠约7cm,慢慢灌入直肠,保留到第二天早晨,经期停用;西药治疗同对照组。连续治疗2个月为1疗程。观测临床表现、卵巢囊肿直径、血清雌二醇、孕酮、尿促卵泡素、促黄体生成素、不良反应。治疗1疗程(2个月),判定疗效。[结果]治疗组痊愈32例,有效6例,无效2例,总有效率95.00%;对照组痊愈15例,有效7例,无效8例,总有效率73.33%;治疗组疗效优于对照组(P<0.05)。卵巢囊肿直径、E_2、P、FSH、LH两组均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.01)。[结论]妇科消囊汤联合西药治疗卵巢囊肿,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Fuke Xiaonang decoction combined with western medicine on ovarian cyst. [Method] Seventy outpatients were randomly divided into two groups by drawing lots according to the order of visiting. Control group 30 cases of cefuroxime 1.5 g, ornidazole 0.5 g + saline250 mL, intravenous drip, 2 times/d. In the treatment group, 40 cases of gynecological Fuke Xiaonang decoction(Lujiaoshuang, Huangqi, Baizhu, Fuling, Tusizi each 18 g, Bajitian, Guizhi, Danshen, Yuxingcao each 13 g Zhigancao 8 g) were decocted with water 300 mL, 100 mL/time, and divided into two groups in the morning and evening; 100 mL was heated to 38 C, before and after defecation, the enema bag was connected with one-time anal canal, and then lubricated with paraffin oil, it was inserted into the rectum slowly, Two days in the morning, the menstrual period was discontinued; western medicine treatment was the same as the control group. Continuous treatment for 2 months is a course of treatment. Clinical manifestations, ovarian cyst diameter, serum estradiol, progesterone, urinary follicle stimulating hormone, luteinizing hormone and adverse reactions were observed. One course of treatment(2 months) was used to determine the curative effect. [Result] In the treatment group, 32 cases were cured, 6 cases were effective, 2 cases were ineffective,the total effective rate was 95.00%. In the control group, 15 cases were cured, 7 cases were effective and8 cases were ineffective, the total effective rate was 73.33%. The curative effect of the treatment group was better than that of the control group(P<0.05). The diameter of ovarian cyst, E2, P, FSH and LH were improved in both groups(P<0.05, P<0.01). The improvement in the treatment group was better than that in the control group(P<0.01). [Conclusion] Fuke Xiaonang decoction combined with western medicine in the treatment of ovarian cyst has satisfactory curative effect and no serious adverse reactions, which is worthy of promotion.
[Objective] To observe the curative effect of Fuke Xiaonang decoction combined with western medicine on ovarian cyst. [Method] Seventy outpatients were randomly divided into two groups by drawing lots according to the order of visiting. Control group 30 cases of cefuroxime 1.5 g, ornidazole 0.5 g + saline250 mL, intravenous drip, 2 times/d. In the treatment group, 40 cases of gynecological Fuke Xiaonang decoction(Lujiaoshuang, Huangqi, Baizhu, Fuling, Tusizi each 18 g, Bajitian, Guizhi, Danshen, Yuxingcao each 13 g Zhigancao 8 g) were decocted with water 300 mL, 100 mL/time, and divided into two groups in the morning and evening; 100 mL was heated to 38 C, before and after defecation, the enema bag was connected with one-time anal canal, and then lubricated with paraffin oil, it was inserted into the rectum slowly, Two days in the morning, the menstrual period was discontinued; western medicine treatment was the same as the control group. Continuous treatment for 2 months is a course of treatment. Clinical manifestations, ovarian cyst diameter, serum estradiol, progesterone, urinary follicle stimulating hormone, luteinizing hormone and adverse reactions were observed. One course of treatment(2 months) was used to determine the curative effect. [Result] In the treatment group, 32 cases were cured, 6 cases were effective, 2 cases were ineffective,the total effective rate was 95.00%. In the control group, 15 cases were cured, 7 cases were effective and8 cases were ineffective, the total effective rate was 73.33%. The curative effect of the treatment group was better than that of the control group(P<0.05). The diameter of ovarian cyst, E2, P, FSH and LH were improved in both groups(P<0.05, P<0.01). The improvement in the treatment group was better than that in the control group(P<0.01). [Conclusion] Fuke Xiaonang decoction combined with western medicine in the treatment of ovarian cyst has satisfactory curative effect and no serious adverse reactions, which is worthy of promotion.
引文
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[15]高学敏.中药学[M].北京:中国中医药出版社,2007.
[2]黄臣,盛晓艳.腹腔镜术前中药灌肠治疗子宫内膜异位囊肿的临床研究[J].深圳中西医结合杂志,2018,28(13):102-103.
[3]康淑芳.卵巢囊肿诊断及治疗技术[J].中国中医药咨讯,2010,2(18):30.
[4]曾雪英.卵巢囊肿的临床特点及诊治体会[J].医学信息(上旬刊),2011,24(1):364.
[5]胡辉权,彭勇,龙琼先.1026例卵巢囊肿的临床病理分析[J].西部医学,2012,24(5):888-890.
[6]王荐.雌激素、孕激素、催产素和催乳素[J].生物学通报,2004,39(2):60.
[7]乐杰.妇产科学[M].北京:人民卫生出版社,2008:282.
[8]张晓娜.66例卵巢囊肿的临床及病理特点分析[J].中外医疗,2010,29(19):74.
[9]侯桂祥,任宇霞.146例卵巢囊肿临床病理特点与分析[J].人人健康:医学导刊,2008(5):19-20.
[10]郝凤英.不同止血方法对卵巢囊肿术后性激素水平变化的影响[J].中国医科大学学报,2012,41(1):91-92.
[11]郑曙光.头孢呋辛临床应用[J].世界最新医学信息文摘:电子版,2013,13(1):295-296.
[12]田怀平,王美纳.奥硝唑的药理作用及临床应用[J].中国药房,2003,14(1):50-52.
[13]周仲瑛.中医内科学[M].北京:中国中医药出版社,2004:287.
[14]潘虹霞,肖江,陈志明.中药灌肠疗法在临床上的运用[J].中医外治杂志,2009,18(6):56-57.
[15]高学敏.中药学[M].北京:中国中医药出版社,2007.