周贤梅教授应用五味子汤治疗特发性肺纤维化的临床经验
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摘要
周贤梅教授认为特发性肺纤维化属于中医学"肺痹""肺痿"范畴,病机为本虚标实之证,本虚为肺脾肾亏虚,标实为痰、热、瘀痹阻肺络。本病治疗总以益气养阴、活血化痰通络为要。在临床中喜用五味子汤治疗特发性肺纤维化,五味子汤出自《圣济总录》,具有益气养阴、止咳平喘、活血化痰之效,可以获得较为明显的临床效果。在临床使用中,要注意根据特发性肺纤维化患者的分期及症状的轻重进行加减用药。
Professor ZHOU Xianmei believes that idiopathic pulmonary fibrosis belongs to the category of "lung bi" and "lung flaccidity" in traditional Chinese medicine. The pathogenesis is deficiency of vital qi and excess of pathogenic qi. The deficiency of vital qi is deficiency of lung, spleen and kidney, and excess of pathogenic qi is lung collaterals injured by phlegm, heat and stasis. The treatment of this disease is based on the principle of benefiting qi and nourishing yin, promoting blood circulation, dissipating phlegm for removing obstruction in collaterals. Wuweizi decoction is often used in the treatment of this disease. Wuweizi decoction is derived from the book of Shengji Zonglu, which has the effect of tonifying qi and nourishing yin, relieving cough and relieving asthma, activating blood and reducing phlegm, and can obtain more obvious clinical effect. It is very important to pay attention to the addition and subtraction of drugs according to the stage of pulmonary fiber patients and the severity of symptoms in clinical.
Professor ZHOU Xianmei believes that idiopathic pulmonary fibrosis belongs to the category of "lung bi" and "lung flaccidity" in traditional Chinese medicine. The pathogenesis is deficiency of vital qi and excess of pathogenic qi. The deficiency of vital qi is deficiency of lung, spleen and kidney, and excess of pathogenic qi is lung collaterals injured by phlegm, heat and stasis. The treatment of this disease is based on the principle of benefiting qi and nourishing yin, promoting blood circulation, dissipating phlegm for removing obstruction in collaterals. Wuweizi decoction is often used in the treatment of this disease. Wuweizi decoction is derived from the book of Shengji Zonglu, which has the effect of tonifying qi and nourishing yin, relieving cough and relieving asthma, activating blood and reducing phlegm, and can obtain more obvious clinical effect. It is very important to pay attention to the addition and subtraction of drugs according to the stage of pulmonary fiber patients and the severity of symptoms in clinical.
引文
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[4]王步青,薛勤梅.特发性肺纤维化证候规律性的统计学分析研究[J].光明中医,2014,29(12):2548-2550.
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[10]丁明桥,许朝霞,李晓红.肺间质纤维化中医分期辨证论治[J].湖北中医杂志,2007,29(11):41-42.
[11]石晓乐,曲妮妮,庞立建,等.特发性肺纤维化“肺肾阴虚、痰瘀伏络”病机探识[J].吉林中医药,2014,34(3):220-222.
[12]褚栩霞,杨珺超.宋康教授治疗特发性肺纤维化经验探析[J].浙江中医药大学学报,2017,41(3):205-207.
[13]曹爱玲.“麦味养肺汤”治疗特发性肺纤维化气阴两虚证的临床疗效观察[D].南京:南京中医药大学,2018.
[14]刘崇文.益气活血法治疗特发性肺纤维化12例[J].吉林中医药,2004,24(5):24-25.
[15]孟泳,崔应麟,王艳梅.益气养阴法对气阴两虚型特发性肺纤维化缓解期的辅助治疗效果[J].山东医药,2016,56(29):86-88.
[2]NAVARATNAM V,FLEMING K M,WEST J,et al.The rising incidence of idiopathic pulmonary fibrosis in the U.K[J].Thorax,2011,66(6):462-467.
[3]徐鹏翔.王书臣教授治疗慢性咳喘病经验总结及诊治特发性肺纤维化经验的数据挖掘[D].北京:中国中医科学院,2017.
[4]王步青,薛勤梅.特发性肺纤维化证候规律性的统计学分析研究[J].光明中医,2014,29(12):2548-2550.
[5]黄云鉴,龚婕宁.肺纤维化中医病名、病机及证治规律探析[J].辽宁中医药大学学报,2016,18(9):98-100.
[6]张心月,贾新华,王立娟,等.从气血变化看肺间质纤维化[J].中医药学报,2012,40(3):56-57.
[7]李壮花.董瑞治疗特发性肺纤维化经验介绍[J].中医临床研究,2016,8(25):104-105.
[8]曹爱玲,井梦昕,周贤梅.肺间质纤维化古代用药规律研究[J].辽宁中医药大学学报,2017,19(4):114-117.
[9]纪娟,王浩,刘丹丽,等.张念志教授治疗特发性肺纤维化经验[J].中医学报,2017,32(4):517-519.
[10]丁明桥,许朝霞,李晓红.肺间质纤维化中医分期辨证论治[J].湖北中医杂志,2007,29(11):41-42.
[11]石晓乐,曲妮妮,庞立建,等.特发性肺纤维化“肺肾阴虚、痰瘀伏络”病机探识[J].吉林中医药,2014,34(3):220-222.
[12]褚栩霞,杨珺超.宋康教授治疗特发性肺纤维化经验探析[J].浙江中医药大学学报,2017,41(3):205-207.
[13]曹爱玲.“麦味养肺汤”治疗特发性肺纤维化气阴两虚证的临床疗效观察[D].南京:南京中医药大学,2018.
[14]刘崇文.益气活血法治疗特发性肺纤维化12例[J].吉林中医药,2004,24(5):24-25.
[15]孟泳,崔应麟,王艳梅.益气养阴法对气阴两虚型特发性肺纤维化缓解期的辅助治疗效果[J].山东医药,2016,56(29):86-88.