利水化瘀法治疗湿热瘀阻型泌尿系结石的用药
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摘要
目的:研究利水化瘀法治疗湿热瘀阻型泌尿系结石的用药规律,为中医药治疗泌尿系结石提供临床思路。方法:选取2015年4月至2016年4月在广东省第二中医院泌尿外科住院的100例324份电子病历及处方,并行回顾性分析。采用药物频数、频率统计及系统分层聚类分析方法进行分析,并探讨其用药规律。结果:9味药出现频率超过50. 00%,8味药出现频率介于25. 00%～50. 00%,13味药出现频率低于25. 00%。28味中药可以凝聚为4类。结论:利水化瘀法从下焦膀胱湿热瘀阻论治,着重使用膀胱经药物,重视其药物的归经,并且采用地道药材,因地制宜,具有岭南中医药特色。
Objective: To investigate the medication rules of draining water and dissolving stasis therapy in treating the damp-heat and blood stasis obstruction type urolithiasis,which could be the guidance for treating the urinary calculus on TCM. Methods: A total of 100 medical records and 324 prescriptions in our hospital during April 2015 to April 2016 were collected and analyzed. The frequencies and rates were collected and analyzed by the hierarchical cluster for studying the medication rules. Results: The frequency of 9 drugs was over 50. 00%,and 13 drugs less than 25. 00%,as well as 8 drugs between 25. 00% and 50. 00%. Then those 28 drugs were classified into 4 clusters. Conclusion: Focusing on the medicines of bladder meridian,draining water and dissolving stasis therapy was used to treat the urolithiasis on the pathogenesis of damp-heat and blood stasis obstruction type on the lower Jiao,which was concentrated on the channel tropism and adjusted measures to local conditions with Lingnan genuine medicinal materials.
Objective: To investigate the medication rules of draining water and dissolving stasis therapy in treating the damp-heat and blood stasis obstruction type urolithiasis,which could be the guidance for treating the urinary calculus on TCM. Methods: A total of 100 medical records and 324 prescriptions in our hospital during April 2015 to April 2016 were collected and analyzed. The frequencies and rates were collected and analyzed by the hierarchical cluster for studying the medication rules. Results: The frequency of 9 drugs was over 50. 00%,and 13 drugs less than 25. 00%,as well as 8 drugs between 25. 00% and 50. 00%. Then those 28 drugs were classified into 4 clusters. Conclusion: Focusing on the medicines of bladder meridian,draining water and dissolving stasis therapy was used to treat the urolithiasis on the pathogenesis of damp-heat and blood stasis obstruction type on the lower Jiao,which was concentrated on the channel tropism and adjusted measures to local conditions with Lingnan genuine medicinal materials.
引文
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[13]马越,畅洪昇.石韦的临床应用和药理研究[J].江西中医学院学报,2011,23(4):87-90.
[14]江灵礼,苗明三.白茅根化学、药理与临床应用探讨[J].中医学报,2014,29(5):713-715.
[15]张雪,宋玉琴,杨雨婷,等.益母草活血化瘀化学成分与药理作用研究进展[J].药物评价研究,2015,38(2):214-217.
[2]李乃卿.实用中西医结合外科学[M].北京:科学技术文献出版社,2010:715-721.
[3]邓韬,黄琳,林谋清,等.中医临床路径指导治疗泌尿系结石临床观察与分析[J].山东中医药大学学报,2016,40(6):518-521.
[4]张丽,刘辉,于小英.中医对石淋的认识探讨[J].中国当代医药,2011,18(23):25,71.
[5]那彦群,叶章群,孙颖浩,等. 2014版中国泌尿外科疾病诊断治疗指南[M].北京:人民卫生出版社,2014:129-165.
[6]中医内科病证诊断疗效标准编写委员会.石淋的诊断依据、证候分类、疗效评定—中华人民共和国中医药行业标准《中医内科病证诊断疗效标准》(ZY/T001. 1-94)[J].辽宁中医药大学学报,2016,18(8):250.
[7]徐嘉辉.余德钊教授治疗小儿支原体肺炎慢性咳嗽用药规律[J].中医学报,2015,30(1):25-28.
[8]罗旭,刘友江.医疗大数据研究现状及其临床应用[J].医学信息学杂志,2015,36(5):10-14.
[9]吴皓萌,徐志伟,敖海清.肠易激综合征中医证候规律的研究[J].世界中医药,2013,8(2):127-129.
[10]林谋清,赵冬,翟胜,等.三金颗粒剂联合气压弹道碎石术治疗输尿管下段结石144例疗效观察[J].新中医,2013,45(9):52-53.
[11]林谋清.三金颗粒剂联合坦洛新治疗输尿管支架综合征351例[J].中国中医药现代远程教育,2013,11(14):13-14.
[12]黄亮辉,苏琪,赵婷婷,等.海金沙的化学成分及药理活性研究进展[J].中药材,2011,34(1):150-154.
[13]马越,畅洪昇.石韦的临床应用和药理研究[J].江西中医学院学报,2011,23(4):87-90.
[14]江灵礼,苗明三.白茅根化学、药理与临床应用探讨[J].中医学报,2014,29(5):713-715.
[15]张雪,宋玉琴,杨雨婷,等.益母草活血化瘀化学成分与药理作用研究进展[J].药物评价研究,2015,38(2):214-217.