骶尾部皮肤纤毛囊肿1例并文献复习
摘要
目的探讨骶尾部皮肤纤毛囊肿(cutaneous ciliated cyst,CCC)的临床病理学特征、诊断、鉴别诊断及预后。方法回顾性分析1例骶尾部CCC的临床病理学、组织学发生及免疫表型特征并复习相关文献。结果患者女童,11岁,发现骶尾部臀裂处赘生物、盆腔MRI尾骨后软组织内边界清楚的囊肿。镜下见真皮层及皮下组织内囊肿形成,与表皮不相连,囊腔内上皮细胞呈乳头状生长,可见鳞状上皮化生,衬覆上皮类似输卵管上皮,由假复层纤毛柱状上皮及分泌细胞组成,未见胞质内分泌物及顶质分泌,未见肌上皮细胞。免疫表型:上皮细胞表达ER、PAX-8,不表达GCDFP-15、TTF-1。结论骶尾部CCC属罕见的良性囊肿,该例起源于异位的Müllerian上皮,确诊主要依靠病理学形态及免疫表型,手术切除后不复发。
引文
[1]Farmer E R,Helwig E B.Cutaneous ciliated cysts[J].Arch Dermatol,1978,114(114):70-73.
[2]Kim Y,Kim H.The cutaneous ciliated cyst in young male:the possibility of ciliated cutaneous eccrine cyst[J].Case Rep Med,2015,2015:589831.
[3]苗朝阳,李若虹,王建峰,等.皮肤纤毛囊肿一例[J].中华皮肤科杂志,2015,48(3):212-313.
[4]Reserva J L,Carrigg A B,Schnebelen A M,et al.Cutaneous ciliated cyst of the scalp:a case report of a cutaneous ciliated eccrine cyst and a brief review of the literature[J].Am J Dermatopathol,2014,36(8):679-682.
[5]Rodrigo-Nicolás B,Raro J J T,Armengot-CarbóM,et al.Müllerian and eccrine cutaneous ciliated cysts:two different entities?The contribution of WT-1 and PAX8 todiagnosis[J].J Cutan Pathol,2013,40(6):608-610.
[6]Jr B W,Heath J E,Drachenberg C B,et al.Cutaneous ciliated cyst:a case report with focus on mullerian heterotopia and comparison with eccrine sweat glands[J].Am J Dermatopathol,2010,32(7):731-734.
[7]Hung T,Yang A,Binder S W,et al.Cutaneous ciliated cyst on the finger:a cutaneous mullerian cyst[J].Am J Dermatopathol,2012,34(3):335-338.
[8]Jin S O,Bhalla V K,Needham L,et al.Müllerian-type,cutaneous ciliated cyst in the gluteal cleft mimicking a pilonidal cyst[J].Pediatr Surg Int,2014,30(5):545-548.
[9]Perez-Valcarcel J,Peon-Curras G,Sanchez-Arca M E,et al.Scrotal skin ciliated cyst.Report of a case and discussion of the pathogenesis[J].Actas Urol Esp,2008,32(8):843-846.
[10]Hjermstad B M,Helwiq E B.Tailgut cysts.Report of 53 cases[J].Am J Clin Pathol,1988,89(2):139-147.
[2]Kim Y,Kim H.The cutaneous ciliated cyst in young male:the possibility of ciliated cutaneous eccrine cyst[J].Case Rep Med,2015,2015:589831.
[3]苗朝阳,李若虹,王建峰,等.皮肤纤毛囊肿一例[J].中华皮肤科杂志,2015,48(3):212-313.
[4]Reserva J L,Carrigg A B,Schnebelen A M,et al.Cutaneous ciliated cyst of the scalp:a case report of a cutaneous ciliated eccrine cyst and a brief review of the literature[J].Am J Dermatopathol,2014,36(8):679-682.
[5]Rodrigo-Nicolás B,Raro J J T,Armengot-CarbóM,et al.Müllerian and eccrine cutaneous ciliated cysts:two different entities?The contribution of WT-1 and PAX8 todiagnosis[J].J Cutan Pathol,2013,40(6):608-610.
[6]Jr B W,Heath J E,Drachenberg C B,et al.Cutaneous ciliated cyst:a case report with focus on mullerian heterotopia and comparison with eccrine sweat glands[J].Am J Dermatopathol,2010,32(7):731-734.
[7]Hung T,Yang A,Binder S W,et al.Cutaneous ciliated cyst on the finger:a cutaneous mullerian cyst[J].Am J Dermatopathol,2012,34(3):335-338.
[8]Jin S O,Bhalla V K,Needham L,et al.Müllerian-type,cutaneous ciliated cyst in the gluteal cleft mimicking a pilonidal cyst[J].Pediatr Surg Int,2014,30(5):545-548.
[9]Perez-Valcarcel J,Peon-Curras G,Sanchez-Arca M E,et al.Scrotal skin ciliated cyst.Report of a case and discussion of the pathogenesis[J].Actas Urol Esp,2008,32(8):843-846.
[10]Hjermstad B M,Helwiq E B.Tailgut cysts.Report of 53 cases[J].Am J Clin Pathol,1988,89(2):139-147.