早期动态增强CT扫描用于诊断卵巢良恶性肿瘤的价值
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摘要
目的:探讨早期动态增强CT扫描用于诊断卵巢良恶性肿瘤的价值。方法:随机选取2015年5月至2017年5月南京市第二医院收治的卵巢肿块患者60例,均接受早期动态增强CT扫描,对60例患者动态增强CT扫描情况进行统计分析,并对其动态增强CT扫描情况与术后病理诊断符合情况进行分析。结果:恶性肿瘤患者的A期、C期、V期显著强化率均显著高于良性肿瘤、交界性肿瘤患者,差异具有统计学意义(P <0. 05),V期一般强化率显著低于良性肿瘤、交界性肿瘤患者(P <0. 05),但三者的A期、C期一般强化率之间的差异不显著,差异无统计学意义(P> 0. 05),无强化率显著低于良性肿瘤患者,差异具有统计学意义(P <0. 05),但与交界性肿瘤之间的差异不显著,差异无统计学意义(P> 0. 05),而交界性肿瘤患者的C期显著强化率、V期一般强化率又均显著高于良性肿瘤患者,差异具有统计学意义(P <0. 05),无强化率又显著低于良性肿瘤患者,差异具有统计学意义(P <0. 05),但二者的A期显著强化率、一般强化率、C期一般强化率、V期显著强化率之间的差异均不显著,差异无统计学意义(P> 0. 05)。60例患者动态增强CT扫描情况与术后病理诊断符合55例,达到了91. 7%的诊断符合率。结论:早期动态增强CT扫描用于诊断卵巢良恶性肿瘤的价值高。
Objective: To evaluate the value of early dynamic contrast-enhanced CT in the diagnosis of benign and malignant ovarian tumors. Methods: 60 patients with ovarian masses in our hospital from May 2015 to May2017 were randomly selected. All the patients underwent early dynamic enhanced CT scanning. The dynamic enhanced CT scanning results were statistically analyzed,and thecoincidence between dynamic enhanced CT scanning results and postoperative pathologic diagnostic results was analyzed. Results: The stage A,stage C,stage Venhancement rates of patients with malignant tumor were significantly higher than those of patients with benign tumors and borderline tumors,with statistically significant difference( P < 0. 05). The stage Venhancement rate was significantly lower than that of patients with benign tumor,borderline tumors( P < 0. 05). However,the differences in stage A,stage C generally enhancement rates between the three groups were not statistically significant( P > 0. 05). The non-enhancement rateof patients with malignant tumor was significantly lower than that of patients with benign tumor( P < 0. 05),but the difference between patients with malignant tumor and borderline tumor was not statistically significant( P > 0. 05). The stage C,V enhancement rates of patients with borderline tumor were significantly higher than that of patients with benign tumor( P < 0. 05),and non-enhancement rate was significantly lower than that of patients with benign tumors( P < 0. 05),but the differences in stage A significantenhancement rate and general en-hancement rate,stage C general enhancement rate and stage Vsignificant enhancement rate between the two groups were not statistically significant( P > 0. 05). There were 55 cases whose dynamic contrast-enhanced CT scan results and postoperative pathological diagnosis was consistent,the diagnostic coincidence rate of 91. 7%. Conclusions:Early dynamic enhanced CT scan is valuable in the diagnosis of benign and malignantovarian tumors.
Objective: To evaluate the value of early dynamic contrast-enhanced CT in the diagnosis of benign and malignant ovarian tumors. Methods: 60 patients with ovarian masses in our hospital from May 2015 to May2017 were randomly selected. All the patients underwent early dynamic enhanced CT scanning. The dynamic enhanced CT scanning results were statistically analyzed,and thecoincidence between dynamic enhanced CT scanning results and postoperative pathologic diagnostic results was analyzed. Results: The stage A,stage C,stage Venhancement rates of patients with malignant tumor were significantly higher than those of patients with benign tumors and borderline tumors,with statistically significant difference( P < 0. 05). The stage Venhancement rate was significantly lower than that of patients with benign tumor,borderline tumors( P < 0. 05). However,the differences in stage A,stage C generally enhancement rates between the three groups were not statistically significant( P > 0. 05). The non-enhancement rateof patients with malignant tumor was significantly lower than that of patients with benign tumor( P < 0. 05),but the difference between patients with malignant tumor and borderline tumor was not statistically significant( P > 0. 05). The stage C,V enhancement rates of patients with borderline tumor were significantly higher than that of patients with benign tumor( P < 0. 05),and non-enhancement rate was significantly lower than that of patients with benign tumors( P < 0. 05),but the differences in stage A significantenhancement rate and general en-hancement rate,stage C general enhancement rate and stage Vsignificant enhancement rate between the two groups were not statistically significant( P > 0. 05). There were 55 cases whose dynamic contrast-enhanced CT scan results and postoperative pathological diagnosis was consistent,the diagnostic coincidence rate of 91. 7%. Conclusions:Early dynamic enhanced CT scan is valuable in the diagnosis of benign and malignantovarian tumors.
引文
[1]吕铭,张洪标,梁红英等. 16排螺旋CT对卵巢浆液性肿瘤的诊断价值.现代医用影像学,2016,25(2):272-274.
[2]钱跃龙.双排螺旋CT对卵巢良恶性肿瘤的诊断.中国实验诊断学,2017,21(6):1055-1057.
[3]杨宏楷,何永胜,潘少辉等. MRI结合血清CA125对卵巢肿块的定性诊断.中国CT和MRI杂志,2016,14(8):24-27.
[4]郭利清,杨舟.超声造影、CT、MRI在卵巢肿瘤临床应用比较.中国CT和MRI杂志,2016,14(10):92-95.
[5]张晰,柏根基. DWI对卵巢实性肿瘤的诊断价值.中国CT和MRI杂志,2017,15(5):112-114.
[6]周娣,袁肖娜,王海燕等.卵巢原发性肿瘤的CT诊断.医学影像学杂志,2016,26(11):2057-2060.
[7]舒予静,潘永海,何荣业,等. CT在盆腔卵巢附件包块性质鉴别、术前分期中的应用.泰山医学院学报,2017,38(2):205-206.
[8]喻喆,刘泓若,蒋葵,等.依维莫司维持治疗原发性铂类耐药卵巢透明细胞癌一例.中华肿瘤杂志,2017,39(8):634-635.
[9]郑容亮,胡莹莹,张亚锐,等. 18F-脱氧葡萄糖PET/CT联合血清糖类抗原125、人附睾蛋白4检测诊断卵巢恶性肿瘤的价值.肿瘤影像学,2016,25(1):38-44.
[10]许祥航. CT和MRI在卵巢肿瘤诊断中的应用价值比较.现代诊断与治疗,2016,27(11):2127-2128.
[11]李亚辉. CT检查对卵巢肿瘤诊断及鉴别诊断的临床分析.心理医生,2017,23(9):79-80.
[12]朱征涛,邱文伟.超声与MRI在筛查及鉴别卵巢肿瘤良恶性病变中应用研究.中国CT和MRI杂志,2017,15(5):115-117,134.
[13]丁永刚,单凯,蔡金华,等. MSCTA辅助儿童卵巢肿瘤蒂扭转定位诊断及精准手术.局解手术学杂志,2016,25(8):577-580.
[14]应卫,李玉艳,ZHAO Limei等.肿瘤标志物在卵巢肿瘤的诊断及良、恶性鉴别中的作用分析.中国性科学,2014,23(1):21-24.
[15]拜钱,赵国强,金仁波,等.超声对绝经后妇女卵巢肿物的诊断价值及临床分析.中国性科学,2015,24(1):29-32.
[16] Chapel DB,Husain AN,Krausz T,et al. PAX8 Expression in a subset of malignant peritoneal mesotheliomas and benign mesothelium has diagnostic implications in the differential diagnosis of ovarian serous carcinoma. Am J Surg Pathol,2017,41(12):1675-1682.
[17] Jung EJ,Eom HM,Byun JM,et al. Different features of the histopathological subtypes of ovarian tumors in pre-and postmenopausal women. Menopause,2017,100(9):1028-1032.
[18] Noguchi K,Wakai K,Kiyono T,et al. Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients. Int J Oncol,2017,51(6):1731-1738.
[2]钱跃龙.双排螺旋CT对卵巢良恶性肿瘤的诊断.中国实验诊断学,2017,21(6):1055-1057.
[3]杨宏楷,何永胜,潘少辉等. MRI结合血清CA125对卵巢肿块的定性诊断.中国CT和MRI杂志,2016,14(8):24-27.
[4]郭利清,杨舟.超声造影、CT、MRI在卵巢肿瘤临床应用比较.中国CT和MRI杂志,2016,14(10):92-95.
[5]张晰,柏根基. DWI对卵巢实性肿瘤的诊断价值.中国CT和MRI杂志,2017,15(5):112-114.
[6]周娣,袁肖娜,王海燕等.卵巢原发性肿瘤的CT诊断.医学影像学杂志,2016,26(11):2057-2060.
[7]舒予静,潘永海,何荣业,等. CT在盆腔卵巢附件包块性质鉴别、术前分期中的应用.泰山医学院学报,2017,38(2):205-206.
[8]喻喆,刘泓若,蒋葵,等.依维莫司维持治疗原发性铂类耐药卵巢透明细胞癌一例.中华肿瘤杂志,2017,39(8):634-635.
[9]郑容亮,胡莹莹,张亚锐,等. 18F-脱氧葡萄糖PET/CT联合血清糖类抗原125、人附睾蛋白4检测诊断卵巢恶性肿瘤的价值.肿瘤影像学,2016,25(1):38-44.
[10]许祥航. CT和MRI在卵巢肿瘤诊断中的应用价值比较.现代诊断与治疗,2016,27(11):2127-2128.
[11]李亚辉. CT检查对卵巢肿瘤诊断及鉴别诊断的临床分析.心理医生,2017,23(9):79-80.
[12]朱征涛,邱文伟.超声与MRI在筛查及鉴别卵巢肿瘤良恶性病变中应用研究.中国CT和MRI杂志,2017,15(5):115-117,134.
[13]丁永刚,单凯,蔡金华,等. MSCTA辅助儿童卵巢肿瘤蒂扭转定位诊断及精准手术.局解手术学杂志,2016,25(8):577-580.
[14]应卫,李玉艳,ZHAO Limei等.肿瘤标志物在卵巢肿瘤的诊断及良、恶性鉴别中的作用分析.中国性科学,2014,23(1):21-24.
[15]拜钱,赵国强,金仁波,等.超声对绝经后妇女卵巢肿物的诊断价值及临床分析.中国性科学,2015,24(1):29-32.
[16] Chapel DB,Husain AN,Krausz T,et al. PAX8 Expression in a subset of malignant peritoneal mesotheliomas and benign mesothelium has diagnostic implications in the differential diagnosis of ovarian serous carcinoma. Am J Surg Pathol,2017,41(12):1675-1682.
[17] Jung EJ,Eom HM,Byun JM,et al. Different features of the histopathological subtypes of ovarian tumors in pre-and postmenopausal women. Menopause,2017,100(9):1028-1032.
[18] Noguchi K,Wakai K,Kiyono T,et al. Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients. Int J Oncol,2017,51(6):1731-1738.