胱抑素C在神经系统疾病中的作用研究进展
摘要
<正>胱抑素C(Cys C)是半胱氨酸蛋白酶抑制剂家族的重要成员之一,1961年由Clausen在脑脊液(CSF)中首次发现。Cys C主要生理作用是参与细胞内外蛋白水解的调控,从而使细胞免受不适当的内源性或外源性蛋
引文
[1]Saitoh E,Sabatini LM,Eddy RL,et al.The human cystatin C gene(CST3)is a member of the cystatin gene family which is localized on chromosome20[J].Biochem Biophys Res Commun,1989,162(3):1324-1331.
[2]仲信明,夏爱华.血清胱抑素C在诊断糖尿病肾病中的相关性研究[J].医学检验与临床,2008,19(4):49-50.
[3]Stabuc B,Vrhovec L,Stabuc-Silih M,et al.Improved prediction of decreased creatinine clearance by serum cystatin C:use in cancer patients before and during chemotherapy[J].Clin Chem,2000,46(2):193-197.
[4]Mussap M,Plebani M.Biochemistry and clinical role of human cystatin C[J].Crit Rev Clin Lab Sci,2004,41(5/6):467-550.
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[6]Mendiluce A,Bustamante J,Martin D,et al.Cystatin C as a marker of renal function in kidney transplant patients[J].Transplant Proc,2005,37(9):3844-3847.
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[8]侯振江,魏明竞.胱抑素C及其检测方法研究进展[J].国际检验医学志,2007,28(11):1013-1015.
[9]王生余,曾彩虹,刘志红.血清胱抑素C——评价肾功能的新指标[J].肾脏病与透析肾移植杂志,2006,15(4):366-370.
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[11]Xiao D,Liu H,Zhang H,et al.Impact of cystatin C levels on infarct size and hemorrhage volume in acute cerebral stroke[J].J Neurol,2012,259(10):2053-2059.
[12]Zhao DQ,Pan SY,Chen JH,et al.Relationship between cystatin C and cerebral infarction[J].Nan Fang Yi Ke Da Xue Xue Bao,2009,29(4):807-808.
[13]Seliger SL,Longstreth WT Jr,Katz R,et al.Cystatin C and subclinical brain infarction[J].J Am Soc Nephrol,2005,16(12):3721-3727.
[14]刘波,刘瑞珍.胱抑素C与脑血管疾病相关性研究进展[J].中西医结合心脑血管病杂志,2013,11(4):482-484.
[15]Hojs Fabjan T,Penko M,Hojs R.Cystatin C,creatinine,estimated glomerular filtration,and long-term mortality in stroke patients[J].Ren Fail,2014,36(1):81-86.
[16]鲁思文,符布清,罗君,等.急性脑梗死患者血清胱抑素C及血脂水平的观察及意义[J].国际检验医学杂志,2011,32(20):2394-2395.
[17]陈荣波,曾琼,魏丽玲,等.无症状脑梗死患者胱抑素C、同型半胱氨酸和血脂的相关性分析[J].中华脑血管病杂志,2013,7(1):21-24.
[18]巴庆华,滕军放,赵莘瑜,等.短暂性脑缺血发作患者血浆Hcy和血清胱抑素C水平分析[J].郑州大学学报:医学版,2011,46(5):751-753.
[19]Levy E,Jaskolski M,Grubb A.The role of cystatin C in cerebral amyloid angiopathy and stroke:cell biology and animal models[J].Brain Pathol,2006,16(1):60-70.
[20]Kaur G,Levy E.Cystatin C in Alzheimer′s disease[J].Front Mol Neurosci,2012,5:79.
[21]Hua Y,Zhao H,Lu X,et al.Meta-analysis of the cystatin C(CST3)gene G73A polymorphism and susceptibility to Alzheimer′s disease[J].Int J Neurosci,2012,122(8):431-438.
[22]武艳,耿玉兰,闫国超,等.中枢神经系统感染中胱抑素C水平变化的临床意义[J].山东医药,2012,52(16):89-90.
[23]陈华英,林伟华,洪流,等.脑脊液胱抑素C和乳酸脱氢酶在化脓性和病毒性脑膜炎的应用[J].实验与检验医学,2012,30(1):57-58.
[24]徐金敏,陈静,许冉,等.合并阻塞性睡眠呼吸暂停综合征的帕金森病患者血清胱抑素C水平的变化[J].中华神经科杂志,2014,47(6):365-369.
[25]刘娟子,石玉玲,李林海,等.血清胱抑素C对帕金森病的临床诊断价值[J].生物技术通讯,2012,23(01):115-116.
[2]仲信明,夏爱华.血清胱抑素C在诊断糖尿病肾病中的相关性研究[J].医学检验与临床,2008,19(4):49-50.
[3]Stabuc B,Vrhovec L,Stabuc-Silih M,et al.Improved prediction of decreased creatinine clearance by serum cystatin C:use in cancer patients before and during chemotherapy[J].Clin Chem,2000,46(2):193-197.
[4]Mussap M,Plebani M.Biochemistry and clinical role of human cystatin C[J].Crit Rev Clin Lab Sci,2004,41(5/6):467-550.
[5]Simonsen O,Grubb A,Thysell H.The blood serum concentration of cystatin C(gamma-trace)as a measure of the glomerular filtration rate[J].Scand J Clin Lab Invest,1985,45(2):97-101.
[6]Mendiluce A,Bustamante J,Martin D,et al.Cystatin C as a marker of renal function in kidney transplant patients[J].Transplant Proc,2005,37(9):3844-3847.
[7]Grubb AO.Cystatin C-properties and use as diagnostic marker[J].Adv Clin Chem,2000(35):63-99.
[8]侯振江,魏明竞.胱抑素C及其检测方法研究进展[J].国际检验医学志,2007,28(11):1013-1015.
[9]王生余,曾彩虹,刘志红.血清胱抑素C——评价肾功能的新指标[J].肾脏病与透析肾移植杂志,2006,15(4):366-370.
[10]Wada M,Nagasawa H,Kawanami T,et al.Cystatin C as an index of cerebral small vessel disease:results of a cross-sectional study in communitybased Japanese elderly[J].Eur J Neurol,2010,17(3):383-390.
[11]Xiao D,Liu H,Zhang H,et al.Impact of cystatin C levels on infarct size and hemorrhage volume in acute cerebral stroke[J].J Neurol,2012,259(10):2053-2059.
[12]Zhao DQ,Pan SY,Chen JH,et al.Relationship between cystatin C and cerebral infarction[J].Nan Fang Yi Ke Da Xue Xue Bao,2009,29(4):807-808.
[13]Seliger SL,Longstreth WT Jr,Katz R,et al.Cystatin C and subclinical brain infarction[J].J Am Soc Nephrol,2005,16(12):3721-3727.
[14]刘波,刘瑞珍.胱抑素C与脑血管疾病相关性研究进展[J].中西医结合心脑血管病杂志,2013,11(4):482-484.
[15]Hojs Fabjan T,Penko M,Hojs R.Cystatin C,creatinine,estimated glomerular filtration,and long-term mortality in stroke patients[J].Ren Fail,2014,36(1):81-86.
[16]鲁思文,符布清,罗君,等.急性脑梗死患者血清胱抑素C及血脂水平的观察及意义[J].国际检验医学杂志,2011,32(20):2394-2395.
[17]陈荣波,曾琼,魏丽玲,等.无症状脑梗死患者胱抑素C、同型半胱氨酸和血脂的相关性分析[J].中华脑血管病杂志,2013,7(1):21-24.
[18]巴庆华,滕军放,赵莘瑜,等.短暂性脑缺血发作患者血浆Hcy和血清胱抑素C水平分析[J].郑州大学学报:医学版,2011,46(5):751-753.
[19]Levy E,Jaskolski M,Grubb A.The role of cystatin C in cerebral amyloid angiopathy and stroke:cell biology and animal models[J].Brain Pathol,2006,16(1):60-70.
[20]Kaur G,Levy E.Cystatin C in Alzheimer′s disease[J].Front Mol Neurosci,2012,5:79.
[21]Hua Y,Zhao H,Lu X,et al.Meta-analysis of the cystatin C(CST3)gene G73A polymorphism and susceptibility to Alzheimer′s disease[J].Int J Neurosci,2012,122(8):431-438.
[22]武艳,耿玉兰,闫国超,等.中枢神经系统感染中胱抑素C水平变化的临床意义[J].山东医药,2012,52(16):89-90.
[23]陈华英,林伟华,洪流,等.脑脊液胱抑素C和乳酸脱氢酶在化脓性和病毒性脑膜炎的应用[J].实验与检验医学,2012,30(1):57-58.
[24]徐金敏,陈静,许冉,等.合并阻塞性睡眠呼吸暂停综合征的帕金森病患者血清胱抑素C水平的变化[J].中华神经科杂志,2014,47(6):365-369.
[25]刘娟子,石玉玲,李林海,等.血清胱抑素C对帕金森病的临床诊断价值[J].生物技术通讯,2012,23(01):115-116.